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anti-Mitochondrial Antiviral Signaling Protein (MAVS) Antibodies

MAVS encodes an intermediary protein necessary in the virus-triggered beta interferon signaling pathways. Additionally we are shipping MAVS Proteins (8) and MAVS Kits (7) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
MAVS 9677 Q6PFW1
MAVS 228607 Q8VCF0
MAVS 311430 Q66HG9
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Top anti-MAVS Antibodies at antibodies-online.com

Showing 10 out of 186 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated IHC, WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB MAVS Antibody (C-term) (ABIN657705) western blot analysis in Hela cell line lysates (35 µg/lane). This demonstrates the MAVS antibody detected the MAVS protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Immunohistochemistry of VISA in mouse brain tissue with this product at 2.5 μg/ml. Western blot analysis of VISA in rat brain tissue lysate with this product at (A) 0.5, (B) 1 and (C) 2 μg/ml. 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated EIA, IF, IHC (p), WB Immunohistochemistry of VISA in human brain tissue with this product at 5 μg/ml. Western blot analysis of VISA in A20 cell lysate with this product at (A) 0.5, (B) 1 and (C) 2 μg/ml. 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Human Mouse Un-conjugated ICC, IP, IHC, WB Cardif is cleaved in liver of a patient infected by the hepatitis C virus. Protein extracts of liver biopsies from a patient with chronic hepatitis C (CHC) and as a control from a patient with alcoholic hepatitis (AH) were run on a SDS-gel and revealed with anti-Cardif (human), mAb (Adri-1) . The arrows indicate endogenous human full-length or cleaved Cardif.  Picture courtesy of Prof. Darius Moradpour, CHUV, Lausanne. 100 μg Log in to see 5 to 8 Days
$404.25
Details
Mouse Rabbit Un-conjugated WB MOUSE Mavs Antibody (N-term) (ABIN1881530) western blot analysis in mouse spleen tissue lysates (35 µg/lane). This demonstrates the MOUSE Mavs antibody detected the MOUSE Mavs protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p), IHC, WB Brain, cortex: Formalin-Fixed Paraffin-Embedded (FFPE) 0.05 mg Log in to see 5 to 7 Days
$515.81
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated IHC (p), WB Human Brain, Cortex (formalin-fixed, paraffin-embedded) stained with VISA antibody ABIN214018 at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 8 to 10 Days
$451.00
Details

MAVS Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-MAVS Antibodies

  1. Human Polyclonal MAVS Primary Antibody for WB - ABIN657705 : Graef, Vreede, Lau, McCall, Carr, Subbarao, Fodor: The PB2 subunit of the influenza virus RNA polymerase affects virulence by interacting with the mitochondrial antiviral signaling protein and inhibiting expression of beta interferon. in Journal of virology 2010 (PubMed)
    Show all 4 references for ABIN657705

  2. Human Monoclonal MAVS Primary Antibody for ICC, IP - ABIN1169132 : Michallet, Meylan, Ermolaeva, Vazquez, Rebsamen, Curran, Poeck, Bscheider, Hartmann, König, Kalinke, Pasparakis, Tschopp: TRADD protein is an essential component of the RIG-like helicase antiviral pathway. in Immunity 2008 (PubMed)
    Show all 3 references for ABIN1169132

  3. Human Polyclonal MAVS Primary Antibody for EIA, IHC (p) - ABIN501120 : Seth, Sun, Chen: Antiviral innate immunity pathways. in Cell research 2006 (PubMed)
    Show all 3 references for ABIN501120

  4. Human Polyclonal MAVS Primary Antibody for EIA, IF - ABIN501118 : Meylan, Curran, Hofmann, Moradpour, Binder, Bartenschlager, Tschopp: Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus. in Nature 2005 (PubMed)
    Show all 3 references for ABIN501118

  5. Cow (Bovine) Polyclonal MAVS Primary Antibody for IHC, WB - ABIN2783802 : Lad, Yang, Scott, Chao, Correia, de la Torre, Li: Identification of MAVS splicing variants that interfere with RIGI/MAVS pathway signaling. in Molecular immunology 2008 (PubMed)

  6. Mouse (Murine) Polyclonal MAVS Primary Antibody for WB - ABIN1881530 : Ichinohe, Pang, Iwasaki: Influenza virus activates inflammasomes via its intracellular M2 ion channel. in Nature immunology 2010 (PubMed)

More Antibodies against MAVS Interaction Partners

Pig (Porcine) Mitochondrial Antiviral Signaling Protein (MAVS) interaction partners

  1. The authors determined that porcine reproductive and respiratory syndrome virus 3C protease cleaved MAVS at Glu268.

  2. Real-time quantitative PCR analysis indicated that Tibetan porcine IPS-1 (show ISYNA1 Antibodies) mRNA was most abundant in the liver and kidney.

Human Mitochondrial Antiviral Signaling Protein (MAVS) interaction partners

  1. This study identified new functional alterations in antiviral signalling based on MAVS polymorphisms

  2. Data show that the NS3 protein of dengue virus bound to 14-3-3 epsilon protein (14-3-3varepsilon) and prevented translocation of retinoic acid-inducible gene-I protein (RIG-I (show DDX58 Antibodies)) to the adaptor MAVS protein and thereby blocked antiviral signaling.

  3. These results demonstrate that poliovirus infection actively suppresses the host type I interferon (show IFNA Antibodies) response by blocking activation of IRF-3 (show IRF3 Antibodies) and suggests that this is not mediated by cleavage of MDA-5 (show IFIH1 Antibodies) or IPS-1.

  4. Using bone marrow derived macrophages from knockout mice we demonstrate that hBD3 (show DEFB103A Antibodies) suppresses the polyI:C-induced TLR3 (show TLR3 Antibodies) response mediated by TICAM1 (TRIF (show TICAM1 Antibodies)), while exacerbating the cytoplasmic response through MDA5 (IFIH1 (show IFIH1 Antibodies)) and MAVS (IPS1/CARDIF).

  5. Results show MAVS-transmembrane domain is shown to oligomerize in response to changes in the outer mitochondrial lipid membrane properties caused by treatment with mitochondrial reactive oxygen species inducers or by Sendai virus infection.

  6. MARCH5 (show MARCH5 Antibodies) binds MAVS only during viral stimulation when MAVS forms aggregates, and these interactions require the RING domain of MARCH5 (show MARCH5 Antibodies) and the CARD domain of MAVS.

  7. An autoinhibitory mechanism modulates MAVS activity in unstimulated cells and, on viral infection, individual regions of MAVS are released following MAVS filament formation to activate antiviral signalling cascades.

  8. indicate comparable activation of the IFN response by pex (show PHEX Antibodies)- and mito-mitochondrial antiviral-signaling protein in hepatocytes and efficient counteraction of both MAVS species by the HCV nonstructural protein 3 (show HSPB3 Antibodies) protease

  9. MAVS50, exposing a degenerate TRAF (show TRAF1 Antibodies)-binding motif within its N-terminus, effectively competed with full-length MAVS for recruiting TRAF2 (show TRAF2 Antibodies) and TRAF6 (show TRAF6 Antibodies)

  10. IPS-1 induces anticancer activity through upregulation of pro-apoptotic gene TRAIL and downregulation of the anti-apoptotic genes BCL2 (show BCL2 Antibodies), BIRC3 (show BIRC3 Antibodies) and PRKCE (show PRKCE Antibodies) via IRF3 (show IRF3 Antibodies) and IRF7 (show IRF7 Antibodies) in type I interferon (show IFNA Antibodies)-dependent and -independent manners.

Mouse (Murine) Mitochondrial Antiviral Signaling Protein (MAVS) interaction partners

  1. Rotavirus infection in macrophages depend on MAVS but not involve the NLRP3 (show NLRP3 Antibodies) inflammasome nor JNK (show MAPK8 Antibodies) and p38 (show CRK Antibodies) signal pathway.

  2. MARCH5 (show MARCH5 Antibodies) binds MAVS only during viral stimulation when MAVS forms aggregates, and these interactions require the RING domain of MARCH5 (show MARCH5 Antibodies) and the CARD domain of MAVS.

  3. An autoinhibitory mechanism modulates MAVS activity in unstimulated cells and, on viral infection, individual regions of MAVS are released following MAVS filament formation to activate antiviral signalling cascades.

  4. indicate comparable activation of the IFN response by pex (show PHEX Antibodies)- and mito-mitochondrial antiviral-signaling protein in hepatocytes and efficient counteraction of both MAVS species by the HCV nonstructural protein 3 (show HSPB3 Antibodies) protease

  5. Transmembrane motif T6BM2-mediated TRAF6 (show TRAF6 Antibodies) binding is required for MAVS-related antiviral response.

  6. Data show that intracellular adaptor protein Cardif-/- natural killer cells (NK cells) are more apoptotic and less proliferative.

  7. Elucidate the structural mechanism of MAVS polymerization, and explain how an alpha-helical domain uses distinct chemical interactions to form self-perpetuating filaments.

  8. MAVS plays an essential role in host immunity against metapneumovirus infection.

  9. results indicate that Lyn (show LYN Antibodies) plays a positive regulatory role in RIG-I (show DDX58 Antibodies)-mediated interferon (show IFNA Antibodies) expression as a downstream component of IPS-1 (show ISYNA1 Antibodies)

  10. In lung epithelial cells, retinoic acid-inducible gene-1 (show RARRES3 Antibodies) (RIG-I (show DDX58 Antibodies)) was identified as the major RIG-I (show DDX58 Antibodies)-like receptor required for RSV-induced protease expression via MAVS.

MAVS Antigen Profile

Protein Summary

This gene encodes an intermediary protein necessary in the virus-triggered beta interferon signaling pathways. It is required for activation of transcription factors which regulate expression of beta interferon and contributes to antiviral immunity. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with MAVS

  • mitochondrial antiviral signaling protein (MAVS) antibody
  • diphosphoinositol pentakisphosphate kinase 1 (PPIP5K1) antibody
  • mitochondrial antiviral signaling protein (Mavs) antibody
  • cardif antibody
  • D430028G21Rik antibody
  • HISPPD2A antibody
  • hsVIP1 antibody
  • IP6K antibody
  • IPS-1 antibody
  • IPS1 antibody
  • VIP1 antibody
  • Visa antibody

Protein level used designations for MAVS

virus-induced signaling adapter , mitochondrial antiviral-signaling protein , mitochondrial IFN-beta promoter stimulator 1 , IP6 kinase , VIP1 homolog , histidine acid phosphatase domain containing 2A , histidine acid phosphatase domain-containing protein 2A , inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 , inositol pyrophosphate synthase 1 , insP6 and PP-IP5 kinase 1 , CARD adapter inducing interferon beta , CARD adaptor inducing IFN-beta , IFN-B promoter stimulator 1 , interferon beta promoter stimulator protein 1 , putative NF-kappa-B-activating protein 031N , virus-induced signaling adaptor , virus-induced-signaling adapter , IFN-beta promoter stimulator-1 , mitochondrial anti-viral signaling protein , IPS-1 , interferon-beta promoter stimulator protein 1

GENE ID SPECIES
470026 Pan troglodytes
485789 Canis lupus familiaris
717616 Macaca mulatta
100037290 Sus scrofa
9677 Homo sapiens
57506 Homo sapiens
228607 Mus musculus
311430 Rattus norvegicus
618508 Bos taurus
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