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anti-Myosin VI (MYO6) Antibodies

MYO6 encodes a protein involved intracellular vesicle and organelle transport, especially in the hair cell of the inner ear. Additionally we are shipping Myosin VI Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
MYO6 4646 Q9UM54
MYO6 17920  
MYO6 315840  
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Top anti-Myosin VI Antibodies at

Showing 10 out of 46 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IF, IHC (p), WB MYO6 Antibody (C-term R1181)  western blot analysis in MCF-7 cell line lysates (35ug/lane).This demonstrates the MYO6 antibody detected the MYO6 protein (arrow). MYO6 Antibody (C-term R1181) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of MYO6 Antibody (C-term R1181) for immunohistochemistry.  Clinical relevance has not been evaluated. 400 μL Log in to see 10 to 11 Days
Human Rabbit Un-conjugated EIA, IF, IHC (p), WB Confocal immunofluorescent analysis of MYO6 Antibody (C-term) Cat.-No AP52797PU-N with MCF-7 cell followed by Alexa Fluor®488 conjugated Goat anti-Rabbit lgG (green). DAPI was used to stain the cell nuclear (blue). Formalin fixed and paraffin embedded human brain tissue stained with MYO6 Antibody (C-term) followed by peroxidase conjugation of the secondary antibody and DAB staining. 0.4 mL Log in to see 6 to 8 Days
Chicken Rabbit Un-conjugated WB Western blot analysis of MYO6 expression in MCF7 (A) whole cell lysates. 200 μL Log in to see 9 Days
Human Rabbit Un-conjugated ELISA, IHC (p), WB 100 μL Log in to see 14 Days
Human Mouse Un-conjugated ELISA, WB MYO6 monoclonal antibody (M02), clone 2E12. Western Blot analysis of MYO6 expression in MCF-7. Detection limit for recombinant GST tagged MYO6 is 0.3 ng/ml as a capture antibody. 100 μg Log in to see 9 Days
Human Rabbit FITC ICC, IHC, ELISA, WB   200 μL Log in to see 8 to 10 Days
Human Rabbit Un-conjugated IF, IHC, WB 400 μL Log in to see 6 Days
Human Rabbit Un-conjugated IF, IHC, ELISA, WB   200 μL Log in to see 11 to 16 Days
Human Rabbit Un-conjugated EIA, IHC (fro), IP, WB   0.2 mL Log in to see 6 to 8 Days
Human Rabbit FITC IF, IHC, ELISA, WB   200 μL Log in to see 16 Days

MYO6 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Myosin VI Antibodies

  1. Human Polyclonal MYO6 Primary Antibody for EIA, IF - ABIN953576 : Nishikawa, Arimoto, Ikezaki, Sugawa, Ueno, Komori, Iwane, Yanagida: Switch between large hand-over-hand and small inchworm-like steps in myosin VI. in Cell 2010 (PubMed)
    Show all 5 references for ABIN953576

  2. Broad Bean (Vicia faba) Polyclonal MYO6 Primary Antibody for IF, WB - ABIN488010 : Hasson, Mooseker: Porcine myosin-VI: characterization of a new mammalian unconventional myosin. in The Journal of cell biology 1994 (PubMed)
    Show all 2 references for ABIN488010

  3. Human Polyclonal MYO6 Primary Antibody for IF, IHC (p) - ABIN655513 : Cho, Chen: Myosin VI is differentially regulated by DNA damage in p53- and cell type-dependent manners. in The Journal of biological chemistry 2010 (PubMed)

More Antibodies against Myosin VI Interaction Partners

Fruit Fly (Drosophila melanogaster) Myosin VI (MYO6) interaction partners

  1. These observations support the notion that a major function of Myosin VI in the nerve terminal is tethering synaptic vesicles to proper sub-cellular location within the bouton

  2. These data demonstrate that generating an organized and functional actin (show ACTB Antibodies) structure in this cell requires multiple activities coordinated by myosin VI.

  3. The androcam structure and its binding to the myosin VI structural (Insert 2) and regulatory (IQ) light chain sites are distinct from those of calmodulin (show CALM Antibodies).

  4. data indicate that myosin V (show MYO5A Antibodies) and VI, but not II, play related but distinct roles in regulating microtubule (MT)-based mitochondrial movement: they oppose, rather than complement, protracted MT-based movements and perhaps facilitate organelle docking

  5. MyoVI is required for border cell migration where it stabilizes E-cadherin (show CDH1 Antibodies) and Arm.

  6. Myosin VI is crucial for correct cell morphology and maintenance of adhesive cellular contacts within epithelial cell layers.

  7. Myosin VI stabilizes a branched actin network in actin structures (cones) that mediate the separation of the syncytial spermatids. I

  8. The spatial and temporal expression of Myosin VI was examined by expressing a Green Fluorescent Protein tagged Myosin VI molecule, under the control of a Myosin VI-Gal4 (show LGALS4 Antibodies) line.

  9. Data suggest that Echinoid mediates the dimerization of myosin VI/Jaguar in vivo which in turn regulates the reorganization and/or contraction of actin (show ACTB Antibodies) filaments to control changes in cell shape.

  10. Miranda protein forms an apical crescent at interphase, but is ubiquitously localized at prophase in a Myosin-II-dependent manner.

Human Myosin VI (MYO6) interaction partners

  1. study indicates that MYO6 may play an important role in gastric cancer tumorigenesis and may serve as a potential therapeutic target in human gastric cancer.

  2. This study identified an isoform-specific regulatory helix, named the alpha2-linker, that defines specific conformations and hence determines the target selectivity of human myosin VI.

  3. Interaction of myosin VI and its binding partner DOCK7 plays an important role in NGF-stimulated protrusion formation in PC12 cells.

  4. Knockdown of myosin VI significantly suppressed melanoma cell viability and proliferation.

  5. Knockdown of MYO6 markedly reduced cell viability and colony formation, as well as suppressed cell cycle progression in breast cancer cells.

  6. MYO6 was highly expressed in hepatocellular carcinoma.

  7. MYO6 is crucial in maintaining cell cycle and cell growth of lung cancer cells.MYO6 is highly expressed in human lung cancer tissues.

  8. Optineurin binding to my (show OPTN Antibodies)osin VI was also decreased in tissue lysates from sporadic amyotrophic lateral sclerosis spinal cords.

  9. we demonstrate that myosin VI and TAX1BP1 (show TAX1BP1 Antibodies) are recruited to ubiquitylated Salmonella and play a key role in xenophagy

  10. The frameshift deletion in MYO6 was confirmed as the causative variant for this dominant nonsyndromic hearing loss DFNA22 family

Mouse (Murine) Myosin VI (MYO6) interaction partners

  1. Myo1a (show MYO1A Antibodies) and Myo6 play essential roles in response to intestinal mucosal injury

  2. Disruption in optineurin (show OPTN Antibodies) and myosin VI-mediated cellular trafficking is associated with amyotrophic lateral sclerosis.

  3. We postulate that this novel interaction linking MVI with the PKA pathway could be important for targeting AKAP9 (show AKAP9 Antibodies)-PKA complex within cells and/or providing PKA to phosphorylate MVI tail domain.

  4. Dysfunction of myosin VI is associated with slow retinal optic neuropathy and age-related macular degeneration.

  5. homologous pairing and myosin VI-mediated transcriptional pause release account for the rapid and efficient expression of genes induced by an external stimulus

  6. Myosin VI mediates the movement of NHE3 (show SLC9A3 Antibodies) to the microvillus in intestinal epithelial cells.

  7. Report no change in cardiac myosin VI expression in mouse model of dilated cardiomyopathy.

  8. the Trip6-GRIP1-myosin VI interaction and its regulation on F-actin network play a significant role in dendritic morphogenesis

  9. Mutated Pou4f3 (show POU4F3 Antibodies) has a negative role in the promoter activity of Myo6.

  10. homozygous Myo6(tvrm89) mice display reduced ERG a (show ERG Antibodies)-wave and b-wave components, as well as components of the ERG (show ERG Antibodies) attributed to RPE (show RPE Antibodies) function, indicates that myosin 6 (show MYH6 Antibodies) is necessary for the generation of proper responses of the outer retina to light.

Pig (Porcine) Myosin VI (MYO6) interaction partners

  1. Data suggest that cells direct the movement of vesicles around a cell by altering the relative number of myosin Va (show MYO5A Antibodies) from Gallus gallus and myosin VI from Sus scrofa.

  2. A myosin VI deafness mutation, D179Y, uncoupled the release of the ATP hydrolysis product, inorganic phosphate (Pi), from dependency on actin binding and destroyed the ability of single dimeric molecules to move processively on actin filaments.

  3. model reveals that myosin VI, unlike plus-end directed myosins, does not use a pure lever arm mechanism, but instead steps with a mechanism analogous to the kinesin neck-linker uncoupling mode

  4. The stepping dynamics of single quantum-dot-labeled myoV and myoVI motors linked to a common cargo, was studied.

  5. These results suggest that myosin VI kinetics are tuned such that the motor maintains a consistent level of mechanical tension within the cell, a property potentially shared by other mechanosensitive proteins.

  6. a mechanism is proposed of myosin VI stepping that predicts a regulation through load of the motor's roles as transporter and anchor

  7. 2.4-A structure of a truncated version of the reverse-direction myosin motor, myosin VI, that contains the motor domain and binding sites for two calmodulin (show CALM Antibodies) molecules

  8. Data demonstrate that full-length myosin VI is capable of forming stable, processive dimers when monomers are clustered, which move up to 1-2 mum in approximately 30 nm, hand-over-hand steps.

  9. further adaptations within the motor increase the magnitude and variability of the plus-end directed converter movements, and unexpectedly provide the source of the highly variable myosin VI step size

  10. Results suggest that myosin VI and vinculin (show VCL Antibodies) form a molecular apparatus that generates cohesive cell-cell contacts in cultured mammalian epithelia.

Cow (Bovine) Myosin VI (MYO6) interaction partners

  1. MVI, but not myosins IB or IIB, was detected in chromaffin granules isolated from bovine medulla and found to be tightly associated with the granule apical surface.

Myosin VI (MYO6) Antigen Profile

Protein Summary

This gene encodes a protein involved intracellular vesicle and organelle transport, especially in the hair cell of the inner ear. Mutations in this gene have been found in patients with non-syndromic autosomal dominant and recessive hearing loss.

Gene names and symbols associated with anti-Myosin VI (MYO6) Antibodies

  • jaguar (jar) antibody
  • myosin VI (LOC373230) antibody
  • myosin VI (LOC100223124) antibody
  • myosin VI (LOC100351334) antibody
  • myosin VI (myo6) antibody
  • myosin VI (MYO6) antibody
  • myosin VI (Myo6) antibody
  • 95F antibody
  • 95F MHC antibody
  • BC029719 antibody
  • CG5695 antibody
  • CMY6 antibody
  • DFNA22 antibody
  • DFNB37 antibody
  • Dm95F antibody
  • Dm 95F antibody
  • Dmel\\CG5695 antibody
  • Dro95F antibody
  • jag antibody
  • Jaguar antibody
  • Jar antibody
  • M6 antibody
  • Mhc95F antibody
  • ms(3)06746 antibody
  • myosins VI antibody
  • Myosin VI antibody
  • MyoVI antibody
  • RGD1560646 antibody
  • sv antibody
  • Tlc antibody

Protein level used designations for anti-Myosin VI (MYO6) Antibodies

95F myosin , 95F unconventional myosin , CG5695-PB , CG5695-PG , CG5695-PH , CG5695-PI , CG5695-PJ , CG5695-PK , CG5695-PL , CG5695-PM , jar-PB , jar-PG , jar-PH , jar-PI , jar-PJ , jar-PK , jar-PL , jar-PM , myosin 95F , myosin VI , myosin heavy chain , myosin heavy chain at 95F , myosin-VI , unconventional myosin VI , unconventional myosin-6 , unconventional myosin-VI , Snell's waltzer , tailchaser , unconventional myosin

42889 Drosophila melanogaster
373230 Strongylocentrotus purpuratus
100223124 Taeniopygia guttata
100351334 Oryctolagus cuniculus
100554995 Anolis carolinensis
100588526 Nomascus leucogenys
4646 Homo sapiens
17920 Mus musculus
315840 Rattus norvegicus
395487 Gallus gallus
397085 Sus scrofa
481884 Canis lupus familiaris
535127 Bos taurus
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