Myosin VI antibody (AA 1016-1285)

Catalog No. ABIN6144291

Product Details anti-Myosin VI Antibody

Target: Myosin VI (MYO6)

Binding Specificity: AA 1016-1285

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Myosin VI antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: IAQSEAELIS DEAQADLALR RNDGTRPKMT PEQMAKEMSE FLSRGPAVLA TKAAAGTKKY DLSKWKYAEL RDTINTSCDI ELLAACREEF HRRLKVYHAW KSKNKKRNTE TEQRAPKSVT DYDFAPFLNN SPQQNPAAQI PARQREIEMN RQQRFFRIPF IRPADQYKDP QSKKKGWWYA HFDGPWIARQ MELHPDKPPI LLVAGKDDME MCELNLEETG LTRKRGAEIL PRQFEEIWER CGGIQYLQNA IESRQARPTY ATAMLQSLLK

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1016-1285 of human MYO6 (NP_004990.3).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Myosin VI

Target: Myosin VI (MYO6)

Alternative Name: MYO6 (MYO6 Products)

Synonyms: 95F antibody, 95F MHC antibody, CG5695 antibody, Dm 95F antibody, Dm95F antibody, Dmel\\CG5695 antibody, Dro95F antibody, JAG antibody, Jaguar antibody, Jar antibody, M6 antibody, MHC95F antibody, MYOVI antibody, Mhc95F antibody, MyoVI antibody, Myosin VI antibody, jag antibody, ms(3)06746 antibody, myosins VI antibody, DFNA22 antibody, DFNB37 antibody, BC029719 antibody, Tlc antibody, sv antibody, RGD1560646 antibody, CMY6 antibody, jaguar antibody, myosin VI antibody, jar antibody, LOC373230 antibody, MYO6 antibody, myo6 antibody, Myo6 antibody

Background: This gene encodes a reverse-direction motor protein that moves toward the minus end of actin filaments and plays a role in intracellular vesicle and organelle transport. The protein consists of a motor domain containing an ATP- and an actin-binding site and a globular tail which interacts with other proteins. This protein maintains the structural integrity of inner ear hair cells and mutations in this gene cause non-syndromic autosomal dominant and recessive hearing loss. Alternative splicing results in multiple transcript variants encoding distinct isoforms.,MYO6,DFNA22,DFNB37,Myo6-007,Myo6-008,myosin VI,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Motor Proteins,MYO6

Molecular Weight: 145 kDa/146 kDa/148 kDa/149 kDa

Gene ID: 4646

UniProt: Q9UM54

Pathways: Sensory Perception of Sound, Dicarboxylic Acid Transport, Asymmetric Protein Localization