Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
Transcription regulator involved in inner cell mass and embryonic stem (ES) cells proliferation and self-renewal. Additionally we are shipping Nanog Homeobox Antibodies (311) and Nanog Homeobox Kits (5) and many more products for this protein.
Showing 10 out of 23 products:
Human NANOG Protein expressed in Escherichia coli (E. coli) - ABIN667930
Pan, Pei: Identification of two distinct transactivation domains in the pluripotency sustaining factor nanog. in Cell research 2004
Show all 2 references for ABIN667930
the existence of three stable steady states for Nanog levels, which are the same in all the different conditions of the cell-culture medium.
NANOG binds to GLI1 (show GLI1 Proteins) and GLI3 (show GLI3 Proteins) proteins and represses Hedgehog (show SHH Proteins)-mediated transcription.
Tgif1 counterbalances the activity of core pluripotency factors, Oct4, Sox2, and Nanog, in mouse embryonic stem cells.
TLR4 (show TLR4 Proteins) signaling via NANOG cooperates with STAT3 (show STAT3 Proteins) to activate Twist1 (show TWIST1 Proteins) and promote formation of tumor-initiating stem-like cells in livers of mice.
Pluripotency transcription factors Nanog and Oct4 (show POU5F1 Proteins) positively modulate Sod2 (show SOD2 Proteins) gene transcription in induced pluripotent stem cells.
NANOG alone induces germ cells in primed epiblast in vitro by activation of enhancers
Forced expression of Nanog (and Esrrb) resulted in the dispensability of nucleostemin (show E2IG3 Proteins) expression in embryonic stem cells.
Dax1 and Nanog have roles in stabilizing mouse embryonic stem cells and induced pluripotency
Data position Cited2 within the pluripotency gene regulatory network by defining Nanog, Tbx3, and Klf4 as its direct targets and demonstrate that the defects caused by Cited2 depletion are, at least in part, rescued by Nanog constitutive expression.
immunoprecipitation. Our data provide new insights into the expanded regulatory circuitry that coordinates Nanog expression.
The promoter activity of Nanog and Oct4 (show POU5F1 Proteins) were upregulated, and beta-catenin (show CTNNB1 Proteins) was observed to bind to these promoters during H. pylori infection, while a Wnt (show WNT2 Proteins)/beta-catenin (show CTNNB1 Proteins) inhibitor suppressed promoter activity and binding.
ectopic expression of Oct-4 (show POU5F1 Proteins) gene in hAFMSCs with high self-renewal ability could upregulate Nanog and Sox-2 (show SOX2 Proteins) gene expression
Nanog is an oncogene (show RAB1A Proteins) with multiple roles in promoting tumorigenesis and metastasis
The positive correlation among Oct-4 (show POU5F1 Proteins), Nanog, and beta-catenin (show CTNNB1 Proteins) suggests their coordinated role in maintaining proliferation in oral carcinoma cells.
Oct3/4 (show POU5F1 Proteins) and Nanog represent probable CSC markers in HNSCC, which contribute to the development of DNM (show DNM1 Proteins) in part by enhancing cell motility and invasiveness.
The outcomes of this study, for the first time, unravels the importance of particular genomic features in Nanog gene evolution paving roads toward better understanding of stem cell development and human targeted disorder therapy
Magnetofection-mediated NANOG delivery increased proliferation and enhanced the differentiation of hair follicle derived mesenchymal stem cells into smooth muscle cells.
NANOG potentiates the molecular circuitry of tumorigenesis, and thus may represent a novel therapeutic target or biomarker for the diagnosis, prognosis, and treatment outcome of cancer.
NANOG may play a significant role in carcinogenesis via its activation of c-Jun (show JUN Proteins) expression.
NANOG-NUMB-p53 signaling axis is an important regulatory pathway for tumor-initiating cells events in TIC self-renewal and liver tumorigenesis
the functional porcine NANOG that is different in chromosomal structure from mouse and human genes is a single exon gene and encodes the functional NANOG protein.
Results demonstrate that Nanog could interact with and activate other pluripotent genes both in porcine fetal fibroblasts and embryos.
Localisation of NANOG, OCT4 (show POU5F1 Proteins), and E-CADHERIN (show CDH1 Proteins) in porcine pre- and peri (show PLIN1 Proteins)-implantation embryos.
analysis of pluripotency gene expression of OCT4, SOX2 and NANOG and mRNA levels of some of their downstream targets in bovine oocytes and early embryos
Nanog displayed relatively the same methylation levels between sperm and oocytes
Noggin, a cytokine inhibiting the BMP4 pathway, successfully upregulated the relative expression of NANOG mRNA in the ICM explants with respect to controls.
Transcription regulator involved in inner cell mass and embryonic stem (ES) cells proliferation and self-renewal. Imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages. Blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes. Acts as a transcriptional activator or repressor. Binds optimally to the DNA consensus sequence 5'-TAAT-3'. When overexpressed, promotes cells to enter into S phase and proliferation (By similarity).
ES cell-associated protein 4
, early embryo specific expression NK family
, early embryo specific expression NK-type homeobox protein
, homeobox protein NANOG
, homeobox transcription factor Nanog
, homeobox transcription factor Nanog-delta 48
, homeodomain transcription factor Nanog
, homeobox transcription factor NANOG