Neural Precursor Cell Expressed, Developmentally Down-Regulated 8 Proteins (NEDD8)

displays differential expression after induction by nerve growth factor [RGD, Feb 2006].. Additionally we are shipping NEDD8 Antibodies (113) and NEDD8 Kits (5) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
NEDD8 4738 Q15843
NEDD8 25490 Q71UE8
NEDD8 18002 P29595
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Top NEDD8 Proteins at antibodies-online.com

Showing 10 out of 31 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 15 to 19 Days
$319.00
Details
HOST_Escherichia coli (E. coli) Human His tag,SUMO Tag   50 μg Log in to see 4 Days
$88.00
Details
HOST_Escherichia coli (E. coli) Human His tag,SUMO Tag   10 μg Log in to see 15 to 16 Days
$100.00
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human His tag Validation with Western Blot 50 μg Log in to see 10 to 12 Days
$229.85
Details
Yeast Cow His tag   1 mg Log in to see 60 to 71 Days
$2,101.00
Details
Yeast Rabbit His tag   1 mg Log in to see 60 to 71 Days
$2,101.00
Details
Yeast Rat His tag   1 mg Log in to see 60 to 71 Days
$2,101.00
Details

NEDD8 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
, , , , , , , , ,
Rat (Rattus)

Mouse (Murine)

Top referenced NEDD8 Proteins

  1. Human NEDD8 Protein expressed in Escherichia coli (E. coli) - ABIN666733 : Hori, Osaka, Chiba, Miyamoto, Okabayashi, Shimbara, Kato, Tanaka: Covalent modification of all members of human cullin family proteins by NEDD8. in Oncogene 2000 (PubMed)
    Show all 2 references for 666733

More Proteins for Neural Precursor Cell Expressed, Developmentally Down-Regulated 8 (NEDD8) Interaction Partners

Fruit Fly (Drosophila melanogaster) Neural Precursor Cell Expressed, Developmentally Down-Regulated 8 (NEDD8) interaction partners

  1. the Cul1 (show CUL1 Proteins)-based SCF (show KITLG Proteins) complex requires Nedd8 modification for the degradation processes of Ci, Arm, and CycE (show CCNE1 Proteins) in vivo

  2. Genetic analyses indicate that a balance between neddylation and deneddylation maintained by DEN1 (show SENP8 Proteins) is crucial for animal viability.

Human Neural Precursor Cell Expressed, Developmentally Down-Regulated 8 (NEDD8) interaction partners

  1. MKK7 (show MAP2K7 Proteins) undergoes neddylation in human breast cancer cells

  2. complete blocking of CRLs at a higher inhibitor dose-induced cytotoxicity that was amplified by knockdown of CRL (show IL31RA Proteins) regulator Cand1 (show CAND1 Proteins).

  3. In conclusion, the authors revealed that E3 ligase HDM2 promotes NEDD8 NEDDylation of HBx to enhance HBx stability and chromatin localization, which in turn favors HBx-dependent transcriptional regulation, cell proliferation, and hepatitis B virus-driven tumor growth.

  4. CUL5 (show CUL5 Proteins) neddylation may allosterically tune polyubiquitin (show UBB Proteins) chain length and topology.

  5. This study identifies MyD88 (show MYD88 Proteins) as a novel substrate of NEDD8, and demonstrate that MyD88 (show MYD88 Proteins) NEDDylation antagonizes its ubiquitination.

  6. This study provides new knowledge of the CFTR (show CFTR Proteins) biosynthetic pathway. It suggests that SYVN1 (show SYVN1 Proteins) and FBXO2 (show FBXO2 Proteins) represent two distinct multiprotein complexes that may degrade DeltaF508-CFTR (show CFTR Proteins) in airway epithelia and identifies a new role for NEDD8 in regulating DeltaF508-CFTR (show CFTR Proteins) ubiquitination.

  7. Neddylation of Smurf1 (show SMURF1 Proteins) activates its ubiquitin ligase activity and Smurf2 (show SMURF2 Proteins) exerts Nedd8 ligase activity. This study provided new clues of Smurf2 (show SMURF2 Proteins) activation regulation.

  8. Nedd8(Q40E) cannot induce the same structural effect on Cul1 (show CUL1 Proteins)-Rbx1 as wild-type Nedd8.

  9. findings add novel evidence showing, for what we believe the first time, that NEDD8-mediated neddylation is required for normal human endometrial functions

  10. In endothelial dysfunction, HDAC2 (show HDAC2 Proteins) levels were reciprocally regulated by ectopic expression of NEDD8 and the de-NEDDylating enzyme SENP8 (show SENP8 Proteins).

Mouse (Murine) Neural Precursor Cell Expressed, Developmentally Down-Regulated 8 (NEDD8) interaction partners

  1. neural precursor cell expressed developmentally downregulated protein 8 (Nedd8) modification of Cul-5 (show CUL5 Proteins) is required for its interaction with TRAF6 (show TRAF6 Proteins).

  2. Our findings provide mechanistic evidence of the effects of IAP (show ALPI Proteins) antagonists in combination with NAE inhibitors, and demonstrate the potential of a new combination therapy for cancer.

  3. a role of Nedd8 in regulating caspase-1 (show CASP1 Proteins) activation following inflammasome activation

  4. Nedd8 and its associated E2 carrier protein (Ubc12 (show ube2m Proteins)) and E3-SCF (show KITLG Proteins) ligase play a key role in regulating the expression and activity of ENaC (show SCNN1A Proteins) in alveolar pneumocytes.

  5. a new regulatory mechanism of RCAN1 (show RCAN1 Proteins) function

  6. c-Cbl conjugates neural precursor cell-expressed, developmentally downregulated 8 (NEDD8), a ubiquitin-like protein, to TbetaRII at Lys556 and Lys567.

  7. The NEDD8 pathway appears to play an important role in CD4 (show CD4 Proteins)+ T-cell-mediated inflammatory responses

  8. Nedd8 and AhR (show AHR Proteins) localize to overlapping areas in the heart and spinal ganglia, raising the possibility that this interaction may play a role in organogenesis

  9. NEDD8 and ubiquitin function in a redundant manner in controlling receptor endocytic pathways.

  10. SCCRO recruits Ubc12 approximately NEDD8 to the CAND1-Cul1-ROC1 complex but that this is not sufficient to dissociate or overcome the inhibitory effects of CAND1 on cullin neddylation

NEDD8 Protein Profile

Protein Summary

displays differential expression after induction by nerve growth factor

Gene names and symbols associated with NEDD8

  • CG10679 gene product from transcript CG10679-RA (Nedd8)
  • neural precursor cell expressed, developmentally down-regulated 8 (nedd8)
  • neural precursor cell expressed, developmentally down-regulated 8 (NEDD8)
  • Nedd8 (Nedd8)
  • ubiquitin-like protein Nedd8 (nedd8)
  • NEDD8 protein (nedd8)
  • NEDD8-like (LOC100520086)
  • neural precursor cell expressed, developmentally down-regulated 8 (Nedd8)
  • neural precursor cell expressed, developmentally down-regulated gene 8 (Nedd8)
  • CG10679 protein
  • DDBDRAFT_0218116 protein
  • DDBDRAFT_0238041 protein
  • DDB_0218116 protein
  • DDB_0238041 protein
  • Dmel\\CG10679 protein
  • dNEDD8 protein
  • GB17785 protein
  • NEDD-8 protein
  • nedd8 protein
  • Rub1 protein
  • si:zc14a17.5 protein
  • ubiquitin protein

Protein level used designations for NEDD8

CG10679-PA , Nedd8-PA , neural precursor cell-expressed developmentally downregulated , neural precursor cell expressed, developmentally down-regulated 8 , Nedd8 , NEDD8 protein , neddylin , ubiquitin-like protein Nedd8 , NEDD8 , neural precursor cell expressed, developmentally down-regulated gene 8 , NEDD-8 , neural precursor cell expressed developmentally down-regulated protein 8

GENE ID SPECIES
35151 Drosophila melanogaster
368667 Danio rerio
480265 Canis lupus familiaris
549727 Xenopus (Silurana) tropicalis
552822 Apis mellifera
704026 Macaca mulatta
715763 Macaca mulatta
8621655 Dictyostelium discoideum AX4
100301786 Oncorhynchus mykiss
100528101 Ictalurus punctatus
100520086 Sus scrofa
4738 Homo sapiens
25490 Rattus norvegicus
286796 Bos taurus
100009008 Oryctolagus cuniculus
18002 Mus musculus
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