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NAMPT encodes a protein that catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, one step in the biosynthesis of nicotinamide adenine dinucleotide. Additionally we are shipping NAMPT Kits (82) and NAMPT Proteins (56) and many more products for this protein.
Showing 10 out of 310 products:
Human Monoclonal NAMPT Primary Antibody for ICC, FACS - ABIN1169028
Bae, Kim, Kim, Kim, Koo, Jang, Yun, Yoo, Bae: Hypoxic induction of human visfatin gene is directly mediated by hypoxia-inducible factor-1. in FEBS letters 2006
Show all 7 references for ABIN1169028
Human Polyclonal NAMPT Primary Antibody for IHC (p), WB - ABIN652958
Samal, Sun, Stearns, Xie, Suggs, McNiece: Cloning and characterization of the cDNA encoding a novel human pre-B-cell colony-enhancing factor. in Molecular and cellular biology 1994
Show all 3 references for ABIN652958
Human Polyclonal NAMPT Primary Antibody for IHC, ELISA - ABIN1169025
Nowell, Richards, Fielding, Ognjanovic, Topley, Williams, Bryant-Greenwood, Jones: Regulation of pre-B cell colony-enhancing factor by STAT-3-dependent interleukin-6 trans-signaling: implications in the pathogenesis of rheumatoid arthritis. in Arthritis and rheumatism 2006
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Human Monoclonal NAMPT Primary Antibody for ELISA, WB - ABIN2869291
Rongvaux, Shea, Mulks, Gigot, Urbain, Leo, Andris: Pre-B-cell colony-enhancing factor, whose expression is up-regulated in activated lymphocytes, is a nicotinamide phosphoribosyltransferase, a cytosolic enzyme involved in NAD biosynthesis. in European journal of immunology 2003
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Human Monoclonal NAMPT Primary Antibody for EIA, IHC (p) - ABIN336072
Stephens, Vidal-Puig: An update on visfatin/pre-B cell colony-enhancing factor, an ubiquitously expressed, illusive cytokine that is regulated in obesity. in Current opinion in lipidology 2006
Show all 2 references for ABIN336072
Chicken Polyclonal NAMPT Primary Antibody for WB - ABIN2775321
Chen, Chung, Chang, Tsai, Huang, Shin, Lee: Elevated plasma level of visfatin/pre-B cell colony-enhancing factor in patients with type 2 diabetes mellitus. in The Journal of clinical endocrinology and metabolism 2006
Human Polyclonal NAMPT Primary Antibody for WB - ABIN223662
Gesing, Masternak, Wang, Joseph, Leeuwenburgh, Westbrook, Lewinski, Karbownik-Lewinska, Bartke: Expression of key regulators of mitochondrial biogenesis in growth hormone receptor knockout (GHRKO) mice is enhanced but is not further improved by other potential life-extending interventions. in The journals of gerontology. Series A, Biological sciences and medical sciences 2011
Lower apelin (show APLN Antibodies) and higher visfatin plasma levels in high normal blood pressure subjects compared to normal or optimal BP individuals could partially explain the higher cardiovascular risk of the high normal BP group.
Studied levels of salivary visfatin, chemerin (show RARRES2 Antibodies), and progranulin (show GRN Antibodies) and in gingivitis, periodontitis, as well as healthy patients. Salivary progranulin (show GRN Antibodies) levels were similar in all groups; chemerin (show RARRES2 Antibodies) was detected at higher levels in the periodontitis group compared to the gingivitis and the healthy groups; visfatin levels were higher in patients with gingivitis and periodontitis compared to those of healthy subjects.
Administration of JNK (show MAPK8 Antibodies) inhibitor SP600125 or ROS (show ROS1 Antibodies) scavenger tocopherol with TMZ and NAMPT inhibitors substantially attenuated the sensitization of NAMPT inhibitor on TMZ antitumor action. Our data indicate a potential value of NAMPT inhibitors in combined use with TMZ for glioblastoma treatment
Increased circulating visfatin are associated with subsequent decline in renal function in nondiabetic hypertensive patients.
High NAMPT expression is associated with neoplasms.
There is an inverse relationship between the visfatin and undercarboxylated osteocalcin (show BGLAP Antibodies) in type 2 diabetes patients with diabetic kidney disease.
The results demonstrated that SAA (show SAA1 Antibodies) upregulated Visfatin expression in cultured RAW264.7 macrophages and in the primary monocytes.
These findings indicate that genetic variants in PBEF1 gene may modify individual susceptibility to osteoarthritis in the Chinese population.
An increased level of visfatin was a strong risk factor for both early and advanced colorectal cancer in Chinese patients
revealed increased likelihood of metabolic and dyslipidemic manifestations in obese compared to non-obese PCOS patients, while no significant difference was noted in visfatin and resistin (show RETN Antibodies) levels among PCOS patients in terms of co-morbid obesity and in comparison to controls
Visfatin upregulated CD36 (show CD36 Antibodies) and SRA (show MSR1 Antibodies) expression and downregulated ABCA1 (show ABCA1 Antibodies) and ABCG1 (show ABCG1 Antibodies) expression, subsequently increased ox-LDL uptake and decreased cholesterol efflux, and finally promoted foam cell formation via the PI3K- and ERK (show EPHB2 Antibodies)-dependent pathways.
results support a novel, important role for Nampt-mediated NAD(+) biosynthesis in long-term depression and in the function of GluN2B (show GRIN2B Antibodies)-containing NMDARs
extracellular NAMPT can be actively released by melanoma cells in vitro.
We now report that NAMPT/PBEF induces lung NFkappaB transcriptional activities and inflammatory injury via direct ligation of Toll-like receptor 4 (TLR4 (show TLR4 Antibodies)).
Visfatin plays an important role in glucose metabolism via the calcium mediated AMPK (show PRKAA1 Antibodies)-p38 MAPK (show MAPK14 Antibodies) pathway.
Deacetylation of intracellular NAMPT by the mammalian NAD(+)-dependent deacetylase SIRT1 (show SIRT1 Antibodies) predisposes the protein to secretion in adipocytes.
Report retinal toxicity of NAMPT inhibitors.
intracellular NAMPT-NAD(+)-SIRT1 (show SIRT1 Antibodies) cascade improves post-ischaemic neovascularization
Data suggest that CTRP3 (cartducin) up-regulates expression and secretion of adipokines (adiponectin, leptin, visfatin, and apelin) in adipocytes; these responses to CTRP3 are down-regulated by insulin resistance or inhibition of AMPK signaling.
The Nampt activity of visfatin is involved in chondrocyte and osteoblast activation
In a wild boar x Meishan F2 family nicotinamide phosphoribosyltransferase nicotinamide phosphoribosyltransferase SNP 669T>C was associated with muscling, fat deposition, growth and fattening, meat quality and other traits.
cloning and characterization of porcine visfatin and its three alternate splicing variants is reported; sequence analysis indicated that variant 1 is the predominant form among species.
The porcine visfatin gene cannot be considered as a marker of fat accumulation since the highest visfatin expression levels were associated with the leaner (show CACNA1A Antibodies) animals.
Exposure to follicular fluid transiently increased the transcript levels of IL8 (show IL8 Antibodies) and PTGS2 (show PTGS2 Antibodies), and decreased the expression of SOD2 (show SOD2 Antibodies), GPX3 (show GPX3 Antibodies), DAB2 (show DAB2 Antibodies), and NR3C1 (show NR3C1 Antibodies). TNF (show TNF Antibodies) and IL6 (show IL6 Antibodies) levels were also decreased while those of NAMPT were unaffected.
the presence of 35bp-insertion in visfatin gene may influence the birth weight and bodyweight in 6-month-old cows.
These results indicate that mammary epithelial cells express the visfatin protein and secrete them into the milk.
This gene encodes a protein that catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, one step in the biosynthesis of nicotinamide adenine dinucleotide. The protein belongs to the nicotinic acid phosphoribosyltransferase (NAPRTase) family and is thought to be involved in many important biological processes, including metabolism, stress response and aging. This gene has a pseudogene on chromosome 10.
pre-B-cell colony enhancing factor 1
, Nicotinamide phosphoribosyltransferase
, nicotinamide phosphoribosyltransferase
, pre-B cell-enhancing factor
, pre-B-cell colony-enhancing factor 1
, pre-B-cell colony-enhancing factor 1 homolog