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Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. Additionally we are shipping NFIB Kits (11) and NFIB Proteins (6) and many more products for this protein.
Showing 10 out of 54 products:
Human Polyclonal NFIB Primary Antibody for ICC, IF - ABIN4339322
Grabowska, Elliott, DeGraff, Anderson, Anumanthan, Yamashita, Sun, Friedman, Hachey, Yu, Sheehan, Ahn, Raj, Piston, Gronostajski, Matusik: NFI transcription factors interact with FOXA1 to regulate prostate-specific gene expression. in Molecular endocrinology (Baltimore, Md.) 2014
Show all 4 Pubmed References
Human Monoclonal NFIB Primary Antibody for IF, IHC (p) - ABIN518322
Moon, Hwang, Kim, Kim, Lee, Jung, Ko, Han, Noh: NFIB is a potential target for estrogen receptor-negative breast cancers. in Molecular oncology 2011
Cow (Bovine) Polyclonal NFIB Primary Antibody for WB - ABIN2777544
Lazrek, Goffard, Schanen, Karquel, Bocket, Lion, Devaux, Hedouin, Gosset, Hober: Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France. in Diagnostic microbiology and infectious disease 2006
Show all 2 Pubmed References
low expression of NFIB was significantly associated with biologically more aggressive subtypes and, ultimately, poorer survival in lung adenocarcinoma patients
Data indicate that NFIB protein increases EZH2 (show EZH2 Antibodies) protein expression downstream of BRN2 (show POU3F2 Antibodies) protein, which further decreases MITF (show MITF Antibodies) protein levels.
Our study defines new molecular subclasses of ACC (show ACACA Antibodies) characterized by MYBL1 (show MYBL1 Antibodies) rearrangements and 5'-NFIB gene fusions.
In benign prostatic hyperplasia, luminal NFIB loss correlated with more severe disease. in androgen-dependent LNCaP prostate cancer cells demonstrated that 64.3% of NFIB binding sites are associated with AR and FOXA1 binding sites.
These data suggest that germline genetic variation at rs7034162 is important in osteosarcoma metastasis and that NFIB is an osteosarcoma metastasis susceptibility gene.
Further studies also discovered a conserved feedback regulatory circuitry formed by NFIB and miR (show MLXIP Antibodies)-365 in cutaneous squamous cell carcinoma development
multivariate analysis co-overexpression of NFIB, RANK and RANKL (show TNFSF11 Antibodies) significantly increased the risk of metastasis with an odds ratio of 13.59
TGF-beta (show TGFB1 Antibodies)-mediated suppression of ANT2 (show SLC25A5 Antibodies) through NF1 (show NF1 Antibodies)/Smad4 (show SMAD4 Antibodies) complexes contributes to oxidative stress and DNA damage during induction of cellular senescence.
Increased expression of NF1B is associated with pilocytic astrocytoma.
The data demonstrates that the autism spectrum disorder-associated A-C intronic haplotype of the ENGRAILED2 gene is a transcriptional activator, and both CUX1 (show CUX1 Antibodies) and NFIB mediate this activity.
Loss of Nfib resulted in a severe delay in intermediate progenitor cell generation while, conversely, overexpression of NFIX (show MLZE Antibodies) led to precocious intermediate progenitor cell generation.
Knockdown of NFIB in Drosha (show DROSHA Antibodies)-deficient hippocampal neural stem cells restores neurogenesis, suggesting that the Drosha (show DROSHA Antibodies)/NFIB mechanism robustly prevents oligodendrocyte fate acquisition in vivo.
Nfib is necessary and sufficient to increase chromatin accessibility at a large subset of the intergenic regions. Nfib promotes pro-metastatic neuronal gene expression programs and drives the metastatic ability of small cell lung cancer cells.
Loss of Nfib expression resulted in prostatic hyperplasia. NFIB knockdown studies demonstrated that loss of NFIB drives increased AR expression and superinduction of a subset of AR target genes.
Identify regulatory link between Nkx2-1 (show NKX2-1 Antibodies), miR (show MLXIP Antibodies)-200c, and the transcription factors Nfib and Myb (show MYB Antibodies), adding new players to the regulatory mechanisms driven by Nkx2-1 (show NKX2-1 Antibodies) in lung epithelial cells that may have implications in lung development and tumorigenesis.
NFIA (show NFIA Antibodies) and NFIB are endogenously expressed in gradients with high caudo-medial to low rostro-lateral expression ... this expression pattern deviates from that of PAX6 (show PAX6 Antibodies), suggesting that PAX6 (show PAX6 Antibodies) does not drive Nfi (show NFIC Antibodies) expression
NFIB-STAT5 (show STAT5A Antibodies) modules, possibly in conjunction with other transcription factors, control cell-specific genetic programs.
Study revealed both novel and broad functions of NFIB in regulating the generation of cortical projection neurons, including radial glial differentiation, neuronal migration and axon projection
downregulation of Ezh2 (show EZH2 Antibodies) transcription by NFIB is an important component of the process of neural progenitor cell differentiation during cortical development
transcription factor NFIB is an unanticipated coordinator of stem cell behaviour
Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.
nuclear factor I/B
, nuclear factor 1 B-type-like
, nuclear factor I-B1
, CCAAT-box binding transcription factor
, CCAAT-box-binding transcription factor
, TGGCA-binding protein
, nuclear factor 1 B-type
, nuclear factor 1/B
, olfactory epithelium nuclear factor I-B