Nuclear Protein, Transcriptional Regulator, 1 Proteins (NUPR1)

Could participate in the response to proapoptotic stimuli and promotes cellular growth in a way that helps the tissue counteract diverse injuries. Additionally we are shipping Nuclear Protein, Transcriptional Regulator, 1 Antibodies (45) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
NUPR1 26471 O60356
NUPR1 56312 Q9WTK0
Rat NUPR1 NUPR1 100912108 O54842;
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Top Nuclear Protein, Transcriptional Regulator, 1 Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$5,442.50
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Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$5,442.50
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HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
$785.40
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Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$405.71
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NUPR1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine)

More Proteins for Nuclear Protein, Transcriptional Regulator, 1 (NUPR1) Interaction Partners

Mouse (Murine) Nuclear Protein, Transcriptional Regulator, 1 (NUPR1) interaction partners

  1. Nupr1 acts as a gene modifier of the effect of Kras(G12D)-induced senescence by regulating Dnmt1 (show DNMT1 Proteins) expression and consequently genome-wide levels of DNA methylation (show HELLS Proteins).

  2. Hepatitis B virus X (HBx) protein can modulate NUPR1 expression through the Smad4 (show SMAD4 Proteins) pathway and NUPR1 has a role in hepatocellular carcinoma progression.

  3. Data indicate that heat shock protein 70 (Hsp70 (show HSP70 Proteins)) is higher in nuclear protein 1 (Nupr1+/-) haplodeficient mice, concomitant with improved insulin (show INS Proteins) sensitivity.

  4. Nupr1 aids oncogenic Kras to bypass senescence in a manner that cooperatively promotes pancreas intraepithelial neoplasia formation.

  5. data shows that p8 deficiency increases ROS (show ROS1 Proteins) and subsequently the expression of anti-oxidative enzymes, such as HO-1 (show HMOX1 Proteins), suggesting an involvement in the anti-oxidative defense.

  6. According to Nupr1 status, KIC mice develop tumours that phenocopy human classical or QM-PDAC, respectively, and present differential drug sensitivity, thus becoming attractive models for preclinical drug trials.

  7. Nupr1 expression is required for IL-1beta-mediated expression of MMP-13. (show MMP13 Proteins)

  8. Inhibition of NUPR1 expression or activity has the potential to protect against the metabolic defects associated with obesity and type 2 diabetes.

  9. a NUPR1/RELB/IER3 stress-related pathway that is required for oncogenic Kras(G12D)-dependent transformation of the pancreas.

  10. progressive PPARalpha (show PPARA Proteins)- and p8-mediated ER stress contribute to the hepatocarcinogenesis in ACOX1 (show ACOX1 Proteins)(-/-) mice

Human Nuclear Protein, Transcriptional Regulator, 1 (NUPR1) interaction partners

  1. dietary protein dilution promotes improved glucose homeostasis through an select nonessential amino acids insufficiency-induced liver NUPR1/FGF21 (show FGF21 Proteins) axis

  2. NUPR1/RELB (show RELB Proteins)/IER3 (show IER3 Proteins)/RUNX2 (show RUNX2 Proteins) pathway has a pivotal role in hepatocarcinogenesis.

  3. Hexavalent Cr(VI) induces Nupr1 and rapidly perturbs gene expression by downregulating H4K16 acetylation, thereby contributing to Cr(VI)-induced carcinogenesis.

  4. findings suggest that local interactions and hydrophobic effects play a major role in determining the electrostatic features of NUPR1, whereas long-range charge contributions appear to be of lesser importance.

  5. Nupr1 acts as a gene modifier of the effect of Kras(G12D)-induced senescence by regulating Dnmt1 (show DNMT1 Proteins) expression and consequently genome-wide levels of DNA methylation (show HELLS Proteins).

  6. Hepatitis B virus X (HBx) protein can modulate NUPR1 expression through the Smad4 (show SMAD4 Proteins) pathway and NUPR1 has a role in hepatocellular carcinoma progression.

  7. Mitochondrial respiratory defects and subsequent retrograde signaling, particularly the NUPR1-granulin (show GRN Proteins) pathway, play pivotal roles in liver cancer progression

  8. Functional characterization of NUPR1L as a new p53 (show TP53 Proteins)-induced gene, which negatively regulates the protumoral factor NUPR1.

  9. Knockdown of Nupr1 inhibited the proliferation and migration of HepG2 hepatocellular carcinoma cells

  10. NUPR1 has been conserved throughout evolution, and over time it has undergone duplications and transpositions to form other transcriptional regulators.

Nuclear Protein, Transcriptional Regulator, 1 (NUPR1) Protein Profile

Protein Summary

Could participate in the response to proapoptotic stimuli and promotes cellular growth in a way that helps the tissue counteract diverse injuries. May contribute to the metastatic phenotype.

Gene names and symbols associated with NUPR1

  • nuclear protein 1, transcriptional regulator (NUPR1)
  • nuclear protein transcription regulator 1 (Nupr1)
  • nuclear protein 1, transcriptional regulator (Nupr1)
  • 2310032H04Rik protein
  • Com1 protein
  • p8 protein

Protein level used designations for NUPR1

candidate of metastasis 1 , nuclear protein 1 , protein p8 , p8 protein , nuclear protein, transcriptional regulator, 1 , Candidate of metastasis 1 , Nuclear transcriptional regulator protein 1 , Protein p8 , nuclear protein 1-like , nuclear proten 1 , nuclear transcriptional regulator protein 1

GENE ID SPECIES
26471 Homo sapiens
56312 Mus musculus
614673 Bos taurus
479793 Canis lupus familiaris
102146652 Macaca fascicularis
100912108 Rattus norvegicus
100064252 Equus caballus
100343968 Oryctolagus cuniculus
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