anti-Nuclear Receptor Binding SET Domain Protein 1 (NSD1) Antibodies

NSD1 encodes a protein containing a SET domain, 2 LXXLL motifs, 3 nuclear translocation signals (NLSs), 4 plant homeodomain (PHD) finger regions, and a proline-rich region. Additionally we are shipping and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
NSD1 64324 Q96L73
NSD1 306764  
NSD1 18193  
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Top anti-NSD1 Antibodies at antibodies-online.com

Showing 10 out of 48 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p) Detection of Human NSD1 by Immunohistochemistry. Samples: FFPE section of human prostate adenocarcinoma. Antibody: Affinity purified rabbit anti-NSD1 ABIN151269 used at a dilution of 1:100. Detection: DAB 0.1 mL Log in to see 7 to 9 Days
$538.13
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (37.62 KDa) . 100 μg Log in to see 11 to 12 Days
$430.00
Details
Human Mouse Un-conjugated WB NSD1 monoclonal antibody (M08), clone 4F1. Western Blot analysis of NSD1 expression in human uterus myoma. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated WB Western blot analysis of extracts of various cells, using NSD1 antibody. 100 μL Log in to see 16 Days
$275.00
Details
Human Mouse Un-conjugated DB 50 μg Log in to see 6 to 8 Days
$285.71
Details
Human Rabbit Un-conjugated IF (p), IHC (p) Formalin-fixed and paraffin embedded rat brain labeled with Anti-NSD1 Polyclonal Antibody, Unconjugated  at 1:200 followed by conjugation to the secondary antibody and DAB staining. Formalin-fixed and paraffin embedded rat brain labeled with Anti-NSD1 Polyclonal Antibody, Unconjugated  at 1:200 followed by conjugation to the secondary antibody and DAB staining. 100 μL Log in to see 3 to 7 Days
$295.90
Details
Human Rabbit Un-conjugated ICC, IF Immunocytochemistry/Immunofluorescence: KMT3B/NSD1 Antibody  - Staining of human cell line HEK 293 shows localization to nucleus & cytosol. 100 μL Log in to see 10 to 13 Days
$439.69
Details
Human Mouse Un-conjugated ELISA, WB   100 μg Log in to see 7 to 9 Days
$537.17
Details
Human Mouse Alkaline Phosphatase (AP) ELISA, WB   100 μL Log in to see 7 to 9 Days
$925.83
Details
Human Mouse FITC ELISA, WB   100 μL Log in to see 7 to 9 Days
$925.83
Details

NSD1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-NSD1 Antibodies

  1. Human Polyclonal NSD1 Primary Antibody for ICC, IF - ABIN151269 : Quintana, Dupuy, Bravo, Casanova, Alameda, Page, Sánchez-Viera, Ramírez, Navarro: A transposon-based analysis of gene mutations related to skin cancer development. in The Journal of investigative dermatology 2013 (PubMed)

  2. Human Monoclonal NSD1 Primary Antibody for ELISA, WB - ABIN528606 : Lu, Jackson, Wang, Yang, Chance, Miyagi, Gudkov, Stark: Regulation of NF-kappaB by NSD1/FBXL11-dependent reversible lysine methylation of p65. in Proceedings of the National Academy of Sciences of the United States of America 2010 (PubMed)

More Antibodies against NSD1 Interaction Partners

Human Nuclear Receptor Binding SET Domain Protein 1 (NSD1) interaction partners

  1. Nuclear receptor binding SET domain protein 1 (NSD1)duplication in 5q35 pathogenic variants could be detected in five out of 43 Silver-Russell syndrome (SRS (show SMS Antibodies)) patients.

  2. Study illustrates the dynamic behavior of the post-SET loop and the presence of a few distinct conformations for NSD1 protein. In every case, the post-SET loop remains in an autoinhibitory position blocking the peptide-binding cleft, suggesting that another interaction is required to optimally position NSD1 in an active conformation.

  3. NSD1 mutation is associated with severe connective tissue laxity including aortic dilatation in Sotos syndrome.

  4. NSD1 mutation is associated with Hyperinsulinemic hypoglycemia.

  5. Studies indicate that the NSD methyltransferases NSD1, NSD2/WHSC1/MMSET (show WHSC1 Antibodies) and NSD3/WHSC1L1 (show WHSC1L1 Antibodies) were overexpressed, amplified or somatically mutated in multiple types of cancer, suggesting their critical role in cancer.

  6. The genome-wide impact of a highly significant NSD1(+/-)-specific signature that differentiates pathogenic NSD1 mutations from controls, benign NSD1 variants and the clinically overlapping Weaver (show KCNJ6 Antibodies) syndrome is described.

  7. The results describe the binding of NSD1, 2 and 3 catalytic domains CD) on histone tails through recognition of histone-lysine and methylation properties.

  8. NSD1 interacted with RNAPII and bound to GSTM3 (show glutathione S-transferase mu 3 (brain) Antibodies) -63A/C TATA box.

  9. Acute myeloid leukemia (show BCL11A Antibodies) can be reproduced in mice by transducing mouse mesenchymal stem cells with the human NUP98 (show NUP98 Antibodies)-NSD1 fusion and the FLT3 (show FLT3 Antibodies)-ITD mutated constracts.

  10. This report describes, for the first time, a Korean family with two generations of Stotos syndrome resulting from a novel intragenic NSD1 mutation.

Mouse (Murine) Nuclear Receptor Binding SET Domain Protein 1 (NSD1) interaction partners

  1. Silencing of Nsd1 followed by LLO stimulation led to increased caspase-1 (show CASP1 Antibodies) activation, enhanced post-translational maturation of IL-1beta (show IL1B Antibodies) and IL-18 (show IL18 Antibodies) and elevated pyroptosis, a form of cell death associated with inflammation.

  2. Nsd1 contains consensus TFII-I (show GTF2I Antibodies) binding sites in the proximal promoters; the chromatin immunoprecipitation analysis showed that TFII-I (show GTF2I Antibodies) transcription factors are recruited to these sites in vivo in Williams-Beuren syndrome.

  3. all of the H3K36-specific methyltransferases, including ASH1L (show ASH1L Antibodies), HYPB (show SETD2 Antibodies), NSD1, and NSD2 (show WHSC1 Antibodies) were inhibited by ubH2A, whereas the other histone methyltransferases, including PRC2, G9a (show EHMT2 Antibodies), and Pr-Set7 (show SETD8 Antibodies) were not affected by ubH2A.

  4. NSD1 interaction with liganded NRs (show SPNS1 Antibodies) including ERa, AR, RARa (show RARA Antibodies), RXRa (show RXRA Antibodies), TRb (show AATF Antibodies), PPARg (show PPARG Antibodies) and VDR (show CYP27B1 Antibodies) is mediated by an LXXLL motif. Interaction with the NR2E/F subfamily including COUP-TFI (show NR2F1 Antibodies), COUP-TFII (show NR2F2 Antibodies), EAR2 (show NR2F6 Antibodies) and TLX (show NR2E1 Antibodies) requires an overlapping F/YSXXLXXL/Y motif.

  5. Data show that nuclear receptor-binding SET domain-containing protein (NSD1) is a developmental regulatory protein with histone methyltransferase activity that exerts function(s) essential for early post-implantation development.

  6. Nizp1 (show ZNF496 Antibodies) contains a novel type of zinc finger motif that functions as a docking site for NSD1

NSD1 Antigen Profile

Protein Summary

This gene encodes a protein containing a SET domain, 2 LXXLL motifs, 3 nuclear translocation signals (NLSs), 4 plant homeodomain (PHD) finger regions, and a proline-rich region. The encoded protein enhances androgen receptor (AR) transactivation, and this enhancement can be increased further in the presence of other androgen receptor associated coregulators. This protein may act as a nucleus-localized, basic transcriptional factor and also as a bifunctional transcriptional regulator. Mutations of this gene have been associated with Sotos syndrome and Weaver syndrome. One version of childhood acute myeloid leukemia is the result of a cryptic translocation with the breakpoints occurring within nuclear receptor-binding Su-var, enhancer of zeste, and trithorax domain protein 1 on chromosome 5 and nucleoporin, 98-kd on chromosome 11. Two transcript variants encoding distinct isoforms have been identified for this gene.

Gene names and symbols associated with NSD1

  • nuclear receptor binding SET domain protein 1 (NSD1) antibody
  • nuclear receptor binding SET domain protein 1 (nsd1) antibody
  • nuclear receptor binding SET domain protein 1 (LOC100355926) antibody
  • nuclear receptor binding SET domain protein 1 (Nsd1) antibody
  • nuclear receptor-binding SET-domain protein 1 (Nsd1) antibody
  • AI528500 antibody
  • ARA267 antibody
  • KMT3B antibody
  • NSD1 antibody
  • SOTOS antibody
  • SOTOS1 antibody
  • STO antibody

Protein level used designations for NSD1

nuclear receptor binding SET domain protein 1 , histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific-like , H3-K36-HMTase , H4-K20-HMTase , NR-binding SET domain-containing protein , androgen receptor coactivator 267 kDa protein , androgen receptor-associated coregulator 267 , androgen receptor-associated protein of 267 kDa , histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific , lysine N-methyltransferase 3B , nuclear receptor-binding SET domain-containing protein 1

GENE ID SPECIES
416214 Gallus gallus
471754 Pan troglodytes
706131 Macaca mulatta
100058570 Equus caballus
100145675 Xenopus (Silurana) tropicalis
100355926 Oryctolagus cuniculus
100461473 Pongo abelii
100477428 Ailuropoda melanoleuca
100538695 Meleagris gallopavo
64324 Homo sapiens
306764 Rattus norvegicus
489094 Canis lupus familiaris
100524976 Sus scrofa
540197 Bos taurus
18193 Mus musculus
Selected quality suppliers for anti-NSD1 (NSD1) Antibodies
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