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anti-Nucleoporin 98kDa (NUP98) Antibodies

Signal-mediated nuclear import and export proceed through the nuclear pore complex (NPC), which is comprised of approximately 50 unique proteins collectively known as nucleoporins. Additionally we are shipping Nucleoporin 98kDa Kits (20) and Nucleoporin 98kDa Proteins (10) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
NUP98 269966  
NUP98 81738 P49793
NUP98 4928 P52948
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Top anti-Nucleoporin 98kDa Antibodies at antibodies-online.com

Showing 10 out of 56 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-NUP98 Antibody Titration: 0.2-1 ug/mlPositive Control: Human Lung 100 μL Log in to see 2 to 3 Days
$289.00
Details
Chicken Rabbit Un-conjugated IF, WB WB Suggested Anti-NUP98 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: Transfected 293T 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rat Un-conjugated DB, ICC, IF, ELISA, WB 100 μg Log in to see 7 to 8 Days
$434.50
Details
Human Mouse Un-conjugated IF, WB 100 μg Log in to see 7 to 8 Days
$434.50
Details
Human Mouse Un-conjugated IF, WB 100 μg Log in to see 7 to 8 Days
$434.50
Details
Human Mouse Un-conjugated IP, WB Western blot detection of NUP98 in Hela, Jurkat and MCF7 cell lysates using NUP98 antibody (1: 1000 diluted).  Predicted band size: 98 kDa.  Observed band size: 98 kDa Immunoprecipitation analysis of Hela cell lysates using NUP98 antibody 100 μL Log in to see 8 to 9 Days
$392.86
Details
Human Rabbit Un-conjugated WB Anti- NUP98 Picoband antibody, Western blotting All lanes: Anti NUP98  at 0.5ug/ml Lane 1: Rat Liver Tissue Lysate at 50ug Lane 2: Mouse Liver Tissue Lysate at 50ug Lane 3: Mouse Lung Tissue Lysate at 50ug Lane 4: A549 Whole Cell Lysate at 40ug Lane 5: SMMC Whole Cell Lysate at 40ug Predicted bind size: 98KD Observed bind size: 98KD 100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Rabbit Un-conjugated WB WB Image Sample (30 ug of whole cell lysate) A: cos 7 7.5% SDS PAGE NUP98 antibody antibody diluted at 1:1000 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details

NUP98 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine) ,
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Rat (Rattus)
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Top referenced anti-Nucleoporin 98kDa Antibodies

  1. Human Monoclonal NUP98 Primary Antibody for IF, WB - ABIN2452065 : Iwamoto, Asakawa, Hiraoka, Haraguchi: Nucleoporin Nup98: a gatekeeper in the eukaryotic kingdoms. in Genes to cells : devoted to molecular & cellular mechanisms 2010 (PubMed)
    Show all 2 references for ABIN2452065

  2. Human Monoclonal NUP98 Primary Antibody for DB, ICC - ABIN2452066 : Fukuhara, Ozaki, Shikata, Katahira, Yoneda, Ogino, Tachibana: Specific monoclonal antibody against the nuclear pore complex protein, nup98. in Hybridoma (2005) 2005 (PubMed)
    Show all 2 references for ABIN2452066

  3. Human Monoclonal NUP98 Primary Antibody for IF, WB - ABIN2452064 : Iwamoto, Asakawa, Ohtsuki, Osakada, Koujin, Hiraoka, Haraguchi: Monoclonal antibodies recognize gly-leu-phe-gly repeat of nucleoporin nup98 of tetrahymena, yeasts, and humans. in Monoclonal antibodies in immunodiagnosis and immunotherapy 2013 (PubMed)
    Show all 2 references for ABIN2452064

  4. Chicken Polyclonal NUP98 Primary Antibody for IF, WB - ABIN2781008 : Pan, Zhu, Gu, Cai, Bai, Yun, Zhu, Chen, Weng, Chen, Xue, Chen: A new fusion gene NUP98-IQCG identified in an acute T-lymphoid/myeloid leukemia with a t(3;11)(q29q13;p15)del(3)(q29) translocation. in Oncogene 2008 (PubMed)

More Antibodies against Nucleoporin 98kDa Interaction Partners

Fruit Fly (Drosophila melanogaster) Nucleoporin 98kDa (NUP98) interaction partners

  1. Nup98 associates and colocalizes with the MBD (show DPEP1 Antibodies)-R2/NSL and Trx (show GSR Antibodies) complexes. Nup98 regulates transcription of Trx (show GSR Antibodies) targets, the Hox (show MSH2 Antibodies) genes.

  2. Nup98, a virus-induced gene, was antiviral against a panel of viruses.

  3. Study analyzed genomic interactions of full-length nucleoporins Nup98, Nup50 (show NUP50 Antibodies), and Nup62 and found that they predominantly interacted with active genes inside the nucleoplasm, particularly those involved in developmental regulation and the cell cycle.

  4. Nup88 (show NUP88 Antibodies) localizes to silent loci, Sec13 (show SEC13 Antibodies), Nup98, and a subset of FG-repeat nucleoporins bind to developmentally regulated genes undergoing transcription induction.

Mouse (Murine) Nucleoporin 98kDa (NUP98) interaction partners

  1. The age-associated accumulation of somatic mutations that occurs in the Nup98-HOXD13 (show HOXD13 Antibodies) (NHD13) mouse model of leukemia progression was significantly elevated by co-expression of a PKR (show EIF2AK2 Antibodies) transgene.

  2. Nup50 (show NUP50 Antibodies) dynamics are independent of importin alpha (show KPNA4 Antibodies), Nup153 (show NUP153 Antibodies), and Nup98, even though the latter two proteins also exhibit transcription-dependent mobility.

  3. Data indicate that loss of cyclin-dependent kinase inhibitor p15 (p15Ink4b (show CDKN2B Antibodies)) collaborates with oncogene (show RAB1A Antibodies) fusion protein Nup98-HoxD13 (show HOXD13 Antibodies) transgene in the development of predominantly myeloid neoplasms.

  4. Homeobox (show PRRX1 Antibodies) partners create more potent NUP98 fusion oncogenes than do non-homeobox (show PRRX1 Antibodies) partners.

  5. findings show that expression of NUP98-HOXD13 (show HOXD13 Antibodies) impairs class switch recombination and reduces the antibody-mediated immune response, in addition to its role in leukemia

  6. Mice expressing both the FLT3 (show FLT3 Antibodies)/ITD and Nup98-HoxD13 (show HOXD13 Antibodies) (NHD13) fusion gene developed acute myeloid leukemia (show BCL11A Antibodies) with 100% penetrance

  7. Data show that NUP98-HOXA10HD, a novel, canonical NUP98-Hox (show MSH2 Antibodies) fusion, significantly enhances the self-renewal capacity of hematopoietic stem cells.

  8. These results clearly demonstrate that Nup98 functions as a novel shuttling cofactor for Crm1 (show XPO1 Antibodies)-mediated nuclear export in conjunction with RanBP3 (show RANBP3 Antibodies).

  9. A mouse model of CML blast crisis induced by cooperation between BCR/ABL (show ABL1 Antibodies) and NUP98/HOXA9 (show HOXA9 Antibodies)

  10. results suggest that Rae1 (show RAE1 Antibodies) and Nup98 are temporal regulators of APC (show APC Antibodies)(Cdh1 (show CDH1 Antibodies)) that maintain euploidy by preventing unscheduled degradation of securin (show PTTG1 Antibodies)

Zebrafish Nucleoporin 98kDa (NUP98) interaction partners

  1. data show that a novel nup98 was identified and it serves a role in nucleocytoplasmic trafficking similar to human NUP98.

Human Nucleoporin 98kDa (NUP98) interaction partners

  1. The results indicate that highly selective targeting of Nup98-fusion proteins to Hox (show MSH2 Antibodies) cluster regions via prebound Crm1 (show XPO1 Antibodies) induces the formation of higher order chromatin structures that causes aberrant Hox (show MSH2 Antibodies) gene regulation.

  2. Despite the difference in localization, all tested Nup98 chimera provoked morphological alterations in the nuclear envelope (NE), in particular affecting the nuclear lamina and the lamina-associated polypeptide 2alpha.

  3. NUP98-HOXA9 (show HOXA9 Antibodies) expression induces myeloid disease.

  4. Overall, these results demonstrate a novel role for FOXK1 (show FOXK2 Antibodies) in regulating the expression of antiviral genes via Nup98, from insects to humans.

  5. deregulation of the retinoid/rexinoid signaling pathway has a major role and may represent a potential therapeutic target for NUP98-RARG (show RARG Antibodies)-mediated transformation

  6. Acute myeloid leukemia (show BCL11A Antibodies) can be reproduced in mice by transducing mouse mesenchymal stem cells with the human NUP98-NSD1 (show NSD1 Antibodies) fusion and the FLT3 (show FLT3 Antibodies)-ITD mutated constracts.

  7. These data reveal an emergent Kap (show CDKN3 Antibodies)-centric barrier mechanism that may underlie mechanistic and kinetic control in the nuclear pore complex.

  8. Vesiculoviral matrix (M) protein (show MYOM2 Antibodies) occupies nucleic acid binding site at nucleoporin (show AGFG2 Antibodies) pair (Rae1 (show RAE1 Antibodies) * Nup98).

  9. NUP98 oncoproteins predispose myeloid cells to oncogenic transformation or malignant progression by promoting whole chromosome instability.

  10. NUP98/JARID1A (show KDM5A Antibodies) is a novel recurrent genetic abnormality in pediatric AMKL (show MKL1 Antibodies)

Xenopus laevis Nucleoporin 98kDa (NUP98) interaction partners

  1. These data support a model in which Nup98 interacts with microtubules and antagonizes MCAK (show KIF2C Antibodies) activity, thus promoting bipolar spindle assembly.

Nucleoporin 98kDa (NUP98) Antigen Profile

Protein Summary

Signal-mediated nuclear import and export proceed through the nuclear pore complex (NPC), which is comprised of approximately 50 unique proteins collectively known as nucleoporins. The 98 kDa nucleoporin is generated through a biogenesis pathway that involves synthesis and proteolytic cleavage of a 186 kDa precursor protein. This cleavage results in the 98 kDa nucleoporin as well as a 96 kDa nucleoporin, both of which are localized to the nucleoplasmic side of the NPC. Rat studies show that the 98 kDa nucleoporin functions as one of several docking site nucleoporins of transport substrates. The human gene has been shown to fuse to several genes following chromosome translocations in acute myelogenous leukemia (AML) and T-cell acute lymphocytic leukemia (T-ALL). This gene is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. Alternative splicing of this gene results in several transcript variants\; however, not all variants have been fully described.

Gene names and symbols associated with NUP98

  • Nucleoporin 98-96 (Nup98-96) antibody
  • nucleoporin 98kDa (Nup98) antibody
  • nucleoporin 98kDa (NUP98) antibody
  • nucleoporin 98 (Nup98) antibody
  • nucleoporin 98 (nup98) antibody
  • Nup98 protein (nup98) antibody
  • 4732457F17 antibody
  • ADIR2 antibody
  • AI849286 antibody
  • CG10198 antibody
  • CG10201 antibody
  • Dmel\\CG10198 antibody
  • GB12688 antibody
  • im:7151238 antibody
  • l(3)95BCd antibody
  • Nup-98 antibody
  • Nup 96 antibody
  • NUP96 antibody
  • NUP98 antibody
  • Nup 98 antibody
  • nup98-96 antibody
  • Nup98-Nup96 antibody
  • Nup98/96 antibody
  • nup145 antibody
  • NUP196 antibody
  • zgc:63593 antibody
  • zgc:113968 antibody

Protein level used designations for NUP98

CG10198-PA , CG10198-PC , CG10198-PD , Nup98 , Nup98-96-PA , Nup98-96-PC , Nup98-96-PD , nucleoporin 98 , nucleoporin 98-96 , nucleoporin98-96 , nucleoporin 98kD , nucleoporin 98kDa , nuclear pore complex protein Nup98-Nup96-like , nuclear pore complex protein Nup98-Nup96 , 98 kDa nucleoporin , nuclear pore complex protein Nup98 , nucleoporin Nup98 , GLFG-repeat containing nucleoporin , Nup98-Nup96

GENE ID SPECIES
42816 Drosophila melanogaster
408335 Apis mellifera
450971 Pan troglodytes
587580 Strongylocentrotus purpuratus
100016427 Monodelphis domestica
100052986 Equus caballus
100090367 Ornithorhynchus anatinus
100414799 Callithrix jacchus
100475098 Ailuropoda melanoleuca
100522560 Sus scrofa
269966 Mus musculus
81738 Rattus norvegicus
777756 Danio rerio
430616 Gallus gallus
4928 Homo sapiens
476822 Canis lupus familiaris
540004 Bos taurus
100343626 Oryctolagus cuniculus
446233 Xenopus laevis
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