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OTU Domain Containing 5 Proteins (OTUD5)

OTUD5 encodes a member of the OTU (ovarian tumor) domain-containing cysteine protease superfamily. Additionally we are shipping OTUD5 Antibodies (43) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
OTUD5 55593 Q96G74
OTUD5 54644 Q3U2S4
OTUD5 363452 Q2YDU3
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Top OTUD5 Proteins at antibodies-online.com

Showing 5 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,622.67
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

OTUD5 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

Rat (Rattus)

More Proteins for OTU Domain Containing 5 (OTUD5) Interaction Partners

Human OTU Domain Containing 5 (OTUD5) interaction partners

  1. Findings have uncovered an apoptotic signaling cascade linking PDCD5 (show PDCD5 Proteins), OTUD5, and p53 (show TP53 Proteins) during genotoxic stress responses.

  2. OTUD5 is required for the stabilization and the activation of a p53 (show TP53 Proteins) response

  3. Here the authors show that phosphorylation of the human deubiquitinase DUBA (OTUD5) at a single residue, Ser177, is both necessary and sufficient to activate the enzyme.

  4. data identify DUBA as a negative regulator of innate immune responses

Mouse (Murine) OTU Domain Containing 5 (OTUD5) interaction partners

  1. data identify DUBA as a cell-intrinsic suppressor of IL-17 (show IL17A Proteins) production

OTUD5 Protein Profile

Protein Summary

This gene encodes a member of the OTU (ovarian tumor) domain-containing cysteine protease superfamily. The OTU domain confers deubiquitinase activity and the encoded protein has been shown to suppress the type I interferon-dependent innate immune response by cleaving the polyubiquitin chain from an essential type I interferon adaptor protein. Cleavage results in disassociation of the adaptor protein from a downstream signaling complex and disruption of the type I interferon signaling cascade. Alternatively spliced transcript variants encoding different isoforms have been described.

Gene names and symbols associated with OTUD5

  • OTU domain containing 5 (OTUD5)
  • OTU domain containing 5a (otud5a)
  • OTU domain containing 5 (Otud5)
  • AA407879 protein
  • AI553596 protein
  • BB114028 protein
  • DUBA protein
  • DXImx46e protein
  • otud5 protein
  • Sfc7 protein
  • si:bz30i22.1 protein
  • si:rp71-30i22.1 protein
  • zgc:154072 protein

Protein level used designations for OTUD5

OTU domain containing 5 , OTU domain-containing protein 5 , OTU domain-containing protein 5-A , deubiquitinating enzyme A , deubiquinating enzyme A , DUBA

GENE ID SPECIES
480911 Canis lupus familiaris
539145 Bos taurus
555459 Danio rerio
737927 Pan troglodytes
55593 Homo sapiens
54644 Mus musculus
363452 Rattus norvegicus
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