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Ovo-Like 2 (Drosophila) Proteins (OVOL2)

DNA-binding protein that binds to the 5'-G[GCT]GGGGG-3' core sequence. Additionally we are shipping OVOL2 Antibodies (26) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
OVOL2 58495 Q9BRP0
OVOL2 107586 Q8CIV7
Rat OVOL2 OVOL2 296201  
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Top OVOL2 Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

OVOL2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for Ovo-Like 2 (Drosophila) (OVOL2) Interaction Partners

Human Ovo-Like 2 (Drosophila) (OVOL2) interaction partners

  1. that the OVOL1 (show OVOL1 Proteins)-OVOL2 axis may actively contribute to cell differentiation and proliferation in the hair bulb

  2. OVOL2 is a colorectal tumor suppressor (show DCC Proteins) that blocks WNT (show WNT2 Proteins) signaling by facilitating the recruitment of histone deacetylase 1 (show HDAC1 Proteins) to the TCF4 (show TCF4 Proteins)-beta-catenin (show CTNNB1 Proteins) complex.

  3. data demonstrate that all four mutated OVOL2 promoters exhibited more transcriptional activity than the corresponding wild-type promoter

  4. Molecular phylogeny of OVOL1 (show OVOL1 Proteins), OVOL2 and OVOL3 (show OVOL3 Proteins) genes illustrates a conserved C2H2 zinc finger domain coupled by hypervariable unstructured regions in humans and other species

  5. Ovol2 directly represses two critical downstream targets, c-Myc (show MYC Proteins) and Notch1 (show NOTCH1 Proteins), thereby suppressing keratinocyte transient proliferation and terminal differentiation, respectively

Mouse (Murine) Ovo-Like 2 (Drosophila) (OVOL2) interaction partners

  1. OVOL2 is a colorectal tumor suppressor (show DCC Proteins) that blocks WNT (show WNT2 Proteins) signaling by facilitating the recruitment of histone deacetylase 1 (show HDAC1 Proteins) to the TCF4 (show TCF4 Proteins)-beta-catenin (show CTNNB1 Proteins) complex.

  2. a Grhl2 (show GRHL2 Proteins)/Ovol2 network controls Cldn4 (show CLDN4 Proteins) and Rab25 (show RAB25 Proteins) expression that facilitates lumen expansion and barrier formation in subtypes of renal epithelia

  3. We show that ER71 (show ETV2 Proteins) directly interacts with OVOL2 and that such interaction is critical for FLK1 (show KDR Proteins)(+) cell generation and their differentiation into downstream cell lineages.

  4. Deletion of Ovol2 blocks mammary ductal morphogenesis, depletes stem and progenitor cell reservoirs, and leads epithelial cells to undergo EMT (show ITK Proteins) .

  5. Ovol2 acts downstream of the BMP pathway in the cell fate decision between neuroectoderm and mesendoderm to ensure proper germ layer development.

  6. Ovol2/MOVO may play an important role in the XY body during spermatogenesis, possibly in the processes of XY body formation and meiotic sex chromosome inactivation.

  7. Ovol2 transcription was dramatically reduced in testes from blind-sterile mice, suggesting that Ovol2 is expressed in male germ cells

  8. Ovol2 is a key regulator of neural development and reveal a previously unexplored role for Ovo genes in mammalian embryogenesis.

  9. Expression of Ovol2 was up-regulated in Ovol1 (show OVOL1 Proteins)-deficient epidermis; Ovol1 (show OVOL1 Proteins) represses the activity of Ovol2 promoter in a DNA binding-dependent manner identifying Ovol2 as a downstream target of Ovol1 (show OVOL1 Proteins).

  10. Ovol2 may play a critical role in vascular angiogenesis during early embryogenesis

OVOL2 Protein Profile

Protein Summary

DNA-binding protein that binds to the 5'-GGGGGG-3' core sequence. Probably acts as a transcription regulator.

Gene names and symbols associated with OVOL2

  • ovo-like 2 (Drosophila) (LOC100231580)
  • ovo-like 2 (ovol2)
  • ovo-like 2 (Drosophila) (OVOL2)
  • ovo-like 2 (Drosophila) (Ovol2)
  • 1700108N11Rik protein
  • 1810007D21Rik protein
  • EUROIMAGE566589 protein
  • M-OVO protein
  • M-OVO-A protein
  • M-OVO-B protein
  • MGC89597 protein
  • MOVO protein
  • movo2 protein
  • Ovo2 protein
  • Zfp339 protein
  • ZNF339 protein

Protein level used designations for OVOL2

ovo-like 2 (Drosophila) , ovo-like 2 , hOvo2 , transcription factor Ovo-like 2 , zinc finger protein 339 , MOVO-B zinc finger protein , MOVO-C zinc finger protein , OVO homolog-like 2 , zinc finger OVO2 , zinc finger protein mOVO

GENE ID SPECIES
100231580 Taeniopygia guttata
448478 Xenopus (Silurana) tropicalis
737338 Pan troglodytes
58495 Homo sapiens
416720 Gallus gallus
485753 Canis lupus familiaris
532761 Bos taurus
107586 Mus musculus
296201 Rattus norvegicus
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