PDZ Binding Kinase (PBK) ELISA Kits

PBKs encodes a serine/threonine kinase related to the dual specific mitogen-activated protein kinase kinase (MAPKK) family. Additionally we are shipping PDZ Binding Kinase Antibodies (139) and PDZ Binding Kinase Proteins (14) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
PBK 55872 Q96KB5
PBK 52033 Q9JJ78
Anti-Rat PBK PBK 290326  
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Top PDZ Binding Kinase ELISA Kits at antibodies-online.com

Showing 2 out of 6 products:

Catalog No. Reactivity Sensitivity Range Quantity Supplier Delivery Price Details
Human
96 Tests Log in to see 2 to 3 Days
$480.00
Details
Mouse
96 Tests Log in to see 15 to 18 Days
$875.60
Details

More ELISA Kits for PDZ Binding Kinase Interaction Partners

Human PDZ Binding Kinase (PBK) interaction partners

  1. Determined the crystal structure of PBK, which has two phospho-mimicking mutations T9E and T198E. The structural data indicated that PBK may assemble into an inactive dimer in alkaline conditions. Analytical size-exclusion chromatography and analytical ultracentrifugation confirmed that PBK exists in a conformational transition between dimers and monomers at different pH conditions.

  2. PBK/TOPK plays a crucial role in tumour malignant potential through its overexpression and highlight its usefulness as a prognostic factor and potential therapeutic target in gastric cancer.

  3. A high PBK expression level was correlated with long overall survival in oral squamous cell carcinoma.

  4. findings suggest that PBK/TOPK plays a crucial role in tumor malignant potential through its overexpression in ESCC

  5. TOPK silencing sensitizes EGFR (show EGFR ELISA Kits)-TKI-resistant lung cancer cells to gefitinib and increases gefitinib efficacy in preclinical lung adenocarcinoma xenograft models.

  6. Study shows that BUB1beta (show BUB1B ELISA Kits) and PDZ binding kinase are up-regulated in breast cancer tumors and their expression is associated with improved overall survival (OS) in basal-like tumors but worse OS in luminal and untreated patients.

  7. Overexpression of Nrf2 (show GABPA ELISA Kits) inhibited the PBK/TOPK KD-induced decrease in cdc2 (show CDK1 ELISA Kits) and cyclin B expression and cell cycle arrest, and blocked ROS (show ROS1 ELISA Kits) production and apoptosis.

  8. The in vitro data have been consistent with a role for PBK/TOPK in facilitating invasion in prostate cancer. PBK could be a prognostic biomarker for prostate cancer that would discriminate aggressive prostate cancer from indolent disease.

  9. TOPK was speculated to be one of a potential marker and therapeutic target in advanced prostate cancer

  10. Authors identified TOPK/PBK, in vitro and in vivo, as the master ZFP linker kinase. Furthermore, they show precise temporal correlation between TOPK activating phosphorylation by Cdk1 (show CDK1 ELISA Kits) and linker phosphorylation in mitosis.

Mouse (Murine) PDZ Binding Kinase (PBK) interaction partners

  1. this study shows that remote ischemic postconditioning protects against renal ischemia/reperfusion injury via activation of TOPK/PTEN/Akt (show AKT1 ELISA Kits) signaling pathway

  2. T-LAK cell-originated protein kinase (TOPK) phosphorylation of MKP1 (show DUSP1 ELISA Kits) protein prevents solar ultraviolet light-induced inflammation through inhibition of the p38 protein (show RNF19A ELISA Kits) signaling pathway.

  3. The TOPK protein is expressed mainly in the cytosol of spermatocytes and spermatids, but not in spermatids and spermatogonia in situ.

  4. Melanoma cell lines expressing with high levels of TOPK are more resistant to As(3+)-induced apoptosis. Therefore, inhibition of TOPK activity combined with As(3+) treatment may be helpful in the treatment of melanomas.

PDZ Binding Kinase (PBK) Antigen Profile

Antigen Summary

This genes encodes a serine/threonine kinase related to the dual specific mitogen-activated protein kinase kinase (MAPKK) family. Evidence suggests that mitotic phosphorylation is required for its catalytic activity. This mitotic kinase may be involved in the activation of lymphoid cells and support testicular functions, with a suggested role in the process of spermatogenesis.

Gene names and symbols associated with PDZ Binding Kinase (PBK) ELISA Kits

  • PDZ binding kinase (PBK) antibody
  • PDZ binding kinase (pbk) antibody
  • PDZ binding kinase (LOC100341076) antibody
  • PDZ binding kinase (Pbk) antibody
  • 2810434B10Rik antibody
  • AW538537 antibody
  • CT84 antibody
  • D14Ertd732e antibody
  • Nori-3 antibody
  • PBK antibody
  • SPK antibody
  • TOPK antibody
  • zgc:92050 antibody

Protein level used designations for PDZ Binding Kinase (PBK) ELISA Kits

PDZ binding kinase , T-LAK cell-originated protein kinase , MAPKK-like protein kinase , cancer/testis antigen 84 , lymphokine-activated killer T-cell-originated protein kinase , serine/threonine protein kinase , spermatogenesis-related protein kinase , PDZ-binding kinase , PBK, PDZ-binding kinase , lymphokine-activated killer T-cell-originated protein kinase homolog

GENE ID SPECIES
422003 Gallus gallus
464496 Pan troglodytes
496810 Xenopus (Silurana) tropicalis
713242 Macaca mulatta
100341076 Oryctolagus cuniculus
100587879 Nomascus leucogenys
55872 Homo sapiens
52033 Mus musculus
360218 Danio rerio
496340 Xenopus laevis
477371 Canis lupus familiaris
100141310 Sus scrofa
534781 Bos taurus
290326 Rattus norvegicus
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