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The protein encoded by PDLIM3 contains a PDZ domain and a LIM domain, indicating that it may be involved in cytoskeletal assembly. Additionally we are shipping PDLIM3 Proteins (5) and PDLIM3 Kits (3) and many more products for this protein.
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Chicken Polyclonal PDLIM3 Primary Antibody for WB - ABIN2786037
Arola, Sanchez, Murphy, Hasle, Li, Elliott, McKenna, Towbin, Bowles: Mutations in PDLIM3 and MYOZ1 encoding myocyte Z line proteins are infrequently found in idiopathic dilated cardiomyopathy. in Molecular genetics and metabolism 2007
This study confirmed that PDLIM3 as genetic modifiers of age at onset of Alzheimer disease.
two abnormal splicing events for actinin-associated LIM protein 3 (show HSPB3 Antibodies) (PDLIM3/ALP) and fibronectin 1 (FN1 (show FN1 Antibodies)) in the skeletal muscles of myotonic dystrophy type 1 patients.
mutations in PDLIM3 and MYPN (show MYPN Antibodies) are infrequent in hypertrophic cardiomyopathies
ZASP (show LDB3 Antibodies)-like motif in actinin-associated LIM protein is required for interaction with the alpha-actinin (show ACTN1 Antibodies) rod and for targeting to the muscle Z-line
Mutations in PDLIM3 and MYOZ1 (show MYOZ1 Antibodies), encoding myocyte Z line proteins, do not play any significant role in the genetic etiology of idiopathic DCM.
upon induction of muscle differentiation a nuclear translocation of smALP from the cytoplasm to the nucleus of C2C12 myoblasts, concomitant to an up-regulation of the protein expression, occurs in parallel with the nuclear accumulation of myogenin (show MYOG Antibodies).
critical role of ALP on muscle differentiation, likely via cytoskeletal regulation of SRF
characterized the internal interaction site of ALP (show CCL21A Antibodies) by NMR
The protein encoded by this gene contains a PDZ domain and a LIM domain, indicating that it may be involved in cytoskeletal assembly. In support of this, the encoded protein has been shown to bind the spectrin-like repeats of alpha-actinin-2 and to colocalize with alpha-actinin-2 at the Z lines of skeletal muscle. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Aberrant alternative splicing of this gene may play a role in myotonic dystrophy.
PDZ and LIM domain protein 3
, alpha-actinin associated LIM protein smooth muscle isoform
, alpha-actinin-associated LIM protein
, alpha-actinin-2-associated LIM protein
, enigma homolog
, actinin-associated LIM protein 4
, actinin alpha 2 associated LIM protein
, actinin-associated LIM protein
, PDZ-LIM protein ALP