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This intronless gene was thought to be a transcribed pseudogene of POU class 5 homeobox 1, however, it has been reported that POU5F1B can encode a functional protein. Additionally we are shipping and many more products for this protein.
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Human Polyclonal POU5F1B Primary Antibody for ELISA - ABIN4239349
Panagopoulos, Möller, Collin, Mertens: The POU5F1P1 pseudogene encodes a putative protein similar to POU5F1 isoform 1. in Oncology reports 2008
The POU5F1B pseudogene is amplified and expressed at a high level in, as well as confers an aggressive phenotype on, GC, and that POU5F1B amplification is associated with a poor prognosis in GC patients.
POU5F1P1 rs10505477 is correlated with survival of gastric cancer patients who receving cisplatin-based chemotherapy after gastrectomy.
Association of rs7014346 in POU5F1P1, rs989902 in PTPN13, and rs7003146 in TCF7L2 with variations in the risk of breast cancer in a Chinese Han population.
Data suggest that expression of Oct4 and NANOG (Nanog homeobox protein) is up-regulated in visceral adipose tissue stem cells in type 2 diabetes as compared to control; expression is also up-regulated in hyperglycemic conditions.
Over-expression of POU5F1P1 in prostatic carcinoma in addition to its genomic location and the putative function of its gene product render POU5F1P1 a good candidate to harbour functional genetic variants which modulate prostatic cancer susceptibility.
that a putative POU5F1P1 protein is localized in the nucleus, acts as a transcriptional activator and regulates the expression in a similar way to the POU5F1 (show POU5F1 Antibodies) isoform 1
This intronless gene was thought to be a transcribed pseudogene of POU class 5 homeobox 1, however, it has been reported that this gene can encode a functional protein. The encoded protein is nearly the same length as and highly similar to the POU class 5 homeobox 1 transcription factor, has been shown to be a weak transcriptional activator and may play a role in carcinogenesis and eye development.
POU 5 domain protein
, POU class 5 homeobox 1 pseudogene 1
, POU domain transcription factor OCT4-pg1
, POU domain transcription factor Oct-4
, POU domain, class 5, transcription factor 1 pseudogene 1
, octamer binding protein 3_like sequence
, putative POU domain, class 5, transcription factor 1B