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This intronless gene was thought to be a transcribed pseudogene of POU class 5 homeobox 1, however, it has been reported that POU5F1B can encode a functional protein. Additionally we are shipping and many more products for this protein.
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Human Polyclonal POU5F1B Primary Antibody for ELISA - ABIN4239349
Panagopoulos, Möller, Collin, Mertens: The POU5F1P1 pseudogene encodes a putative protein similar to POU5F1 isoform 1. in Oncology reports 2008
We identified eight specific CpG sites at 8q24, including six correlated sites in the POU5F1B gene, as well as two CpG sites in intergenic regions, whose DNA methylation (show HELLS Antibodies) levels were associated with prostate cancer risk.
The POU5F1B pseudogene is amplified and expressed at a high level in, as well as confers an aggressive phenotype on, GC, and that POU5F1B amplification is associated with a poor prognosis in GC patients.
POU5F1P1 rs10505477 is correlated with survival of gastric cancer patients who receving cisplatin-based chemotherapy after gastrectomy.
Association of rs7014346 in POU5F1P1, rs989902 in PTPN13, and rs7003146 in TCF7L2 with variations in the risk of breast cancer in a Chinese Han population.
Data suggest that expression of Oct4 and NANOG (Nanog homeobox protein) is up-regulated in visceral adipose tissue stem cells in type 2 diabetes as compared to control; expression is also up-regulated in hyperglycemic conditions.
Over-expression of POU5F1P1 in prostatic carcinoma in addition to its genomic location and the putative function of its gene product render POU5F1P1 a good candidate to harbour functional genetic variants which modulate prostatic cancer susceptibility.
that a putative POU5F1P1 protein is localized in the nucleus, acts as a transcriptional activator and regulates the expression in a similar way to the POU5F1 (show POU5F1 Antibodies) isoform 1
This intronless gene was thought to be a transcribed pseudogene of POU class 5 homeobox 1, however, it has been reported that this gene can encode a functional protein. The encoded protein is nearly the same length as and highly similar to the POU class 5 homeobox 1 transcription factor, has been shown to be a weak transcriptional activator and may play a role in carcinogenesis and eye development.
POU 5 domain protein
, POU class 5 homeobox 1 pseudogene 1
, POU domain transcription factor OCT4-pg1
, POU domain transcription factor Oct-4
, POU domain, class 5, transcription factor 1 pseudogene 1
, octamer binding protein 3_like sequence
, putative POU domain, class 5, transcription factor 1B