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Catalyzes the transfer of phosphatidylcholine between membranes. Additionally we are shipping PCTP Proteins (8) and PCTP Kits (3) and many more products for this protein.
Showing 10 out of 52 products:
Human Polyclonal PCTP Primary Antibody for EIA, WB - ABIN954056
Roderick, Chan, Agate, Olsen, Vetting, Rajashankar, Cohen: Structure of human phosphatidylcholine transfer protein in complex with its ligand. in Nature structural biology 2002
Show all 4 references for ABIN954056
Mutations in PCTP gene is associated with prostate cancer
PC-TP contributes to the racial difference in PAR4 (show PAWR Antibodies)-mediated platelet activation.
crystal structures of human PC-TP in complex with dilinoleoyl-PtdCho or palmitoyl-linoleoyl-PtdCho reveal that a single well-ordered PtdCho molecule occupies a centrally located tunnel
phosphatidylcholine transfer protein gene variants are associated with LDL-peak particle size
Yeast two-hybrid screening using libraries prepared from mouse liver and embryo identified Them2 (thioesterase superfamily member 2 (show ACOT13 Antibodies)) and the homeodomain transcription factor Pax3 (paired box gene 3 (show PAX3 Antibodies)), respectively, as PC-TP-interacting proteins.
Them2 (show ACOT13 Antibodies) and phosphatidylcholine transfer protein regulate lipid and glucose metabolism
PC-TP-THEM2 (show ACOT13 Antibodies) complex reduces phosphorylation and stability of IRS2 (show IRS2 Antibodies) and increases stability of the TSC1 (show TSC1 Antibodies)-TSC2 (show TSC2 Antibodies) complex
Findings support a key role for Pctp in limiting mitochondrial oxidation of fatty acids and thus regulating adaptive thermogenesis in BAT (show BAAT Antibodies).
regulation of cholesterol homeostasis is a physiological function of PC-TP in liver, which can be overcome with a cholesterol-rich lithogenic diet
In Pctp(-/-) mice, there was an accumulation of small alpha-migrating HDL (show HSD11B1 Antibodies) particles. PC-TP participates in HDL (show HSD11B1 Antibodies) reverse cholesterol transport.
PC-TP modulates the development of atherosclerosis, in part by regulating plasma lipid concentrations
NZO-derived PC-TP contained a non-synonymous point mutation that resulted in an Arg120His substitution, which was shared by the related NZB/BlNJ and NZW/LacJ mouse strains.
data support a key biological role for PCTP in the regulation of energy substrate utilization, reflecting increased hepatic triglyceride production in knockout mice.
Catalyzes the transfer of phosphatidylcholine between membranes. Binds a single lipid molecule.
START domain-containing protein 2
, StAR-related lipid transfer (START) domain containing 2
, stAR-related lipid transfer protein 2