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anti-Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 3 (KCNA3) Antibodies

Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Additionally we are shipping KCNA3 Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
KCNA3 3738 P22001
KCNA3 16491 P16390
KCNA3 29731 P15384
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Top anti-KCNA3 Antibodies at antibodies-online.com

Showing 10 out of 96 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of KCNA3 Antibody (Center) in A549 cell line lysates (35ug/lane).This demonstrates the KCNA3 antibody detected the KCNA3 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IF, IHC, ELISA, WB Western blot analysis of extracts from Jurkat cells treated with starved 24h, using Kv1.3/KCNA3 (Phospho-Tyr135) Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human brain, using Kv1.3/KCNA3 (Phospho-Tyr135) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Mouse Un-conjugated WB KCNA3 monoclonal antibody (M01), clone 1D8 Western Blot analysis of KCNA3 expression in HeLa NE. Detection limit for recombinant GST tagged KCNA3 is approximately 0.03 ng/mL as a capture antibody. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated WB KCNA3 Antibody (Center) (ABIN658606) western blot analysis in A549 cell line lysates (35 µg/lane). This demonstrates the KCNA3 antibody detected the KCNA3 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Rabbit Un-conjugated IF, IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human brain tissue, using Kv1.3/KCNA3 (Ab-135) Antibody. The picture on the right is treated with the synthesized peptide. Immunofluorescence analysis of HuvEc cells, using Kv1.3/KCNA3 (Ab-135) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated IHC (p) Anti-KCNA3 / Kv1.3 antibody  ABIN1048981 IHC staining of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Anti-KCNA3 / Kv1.3 antibody  ABIN1048981 IHC staining of human thyroid. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated WB HepG2 lysate probed with Rabbit Anti-KCNA3 polyclonal antibody  at 1:5000 90min in 37˚C 100 μL Log in to see 14 to 21 Days
$269.50
Details
Human Rabbit Un-conjugated IF, WB Immunohistochemistry analyzes of Kv1.3 antibody in paraffin-embedded human brain tissue. 0.1 mg Log in to see 6 to 8 Days
$390.50
Details

KCNA3 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-KCNA3 Antibodies

  1. Human Polyclonal KCNA3 Primary Antibody for WB - ABIN265023 : Stühmer, Ruppersberg, Schröter, Sakmann, Stocker, Giese, Perschke, Baumann, Pongs: Molecular basis of functional diversity of voltage-gated potassium channels in mammalian brain. in The EMBO journal 1989 (PubMed)
    Show all 6 references for ABIN265023

  2. Human Polyclonal KCNA3 Primary Antibody for EIA, WB - ABIN952995 : Wang, Lee, Johnson, Allie, Hu, Calabresi, Nath: Activated T-cells inhibit neurogenesis by releasing granzyme B: rescue by Kv1.3 blockers. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2010 (PubMed)
    Show all 5 references for ABIN952995

  3. Human Monoclonal KCNA3 Primary Antibody for WB - ABIN393258 : Tu, Deutsch: A folding zone in the ribosomal exit tunnel for Kv1.3 helix formation. in Journal of molecular biology 2010 (PubMed)
    Show all 5 references for ABIN393258

  4. Human Polyclonal KCNA3 Primary Antibody for IF, IHC - ABIN1531682 : Folander, Douglass, Swanson: Confirmation of the assignment of the gene encoding Kv1.3, a voltage-gated potassium channel (KCNA3) to the proximal short arm of human chromosome 1. in Genomics 1995 (PubMed)

More Antibodies against KCNA3 Interaction Partners

Human Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 3 (KCNA3) interaction partners

  1. Results contribute to the characterization of leukemic B cells, as it shows that upregulation of Kv1.3 in pathologic B lymphocytes is linked to the oncogenic B-RAF (show SNRPE Antibodies) signaling.

  2. Data suggest that C-terminus is necessary for Kv1.3-induced cell proliferation; the mechanism involves accessibility of key docking sites at the C terminus; phosphorylation of Tyr (show TYR Antibodies)-447 by MAP kinase (show MAPK1 Antibodies) signal cascade appears crucial.

  3. concluded that Kv1.3 may stimulate macrophage migration through the activation of ERK (show EPHB2 Antibodies).

  4. The inhibition of Kv1.3 channels might be involved in antiproliferative and proapoptotic effects of the compounds observed in cancer cell lines expressing these channels.

  5. Kv1.3 channels modulate human vascular smooth muscle cells proliferation independently of mTOR (show FRAP1 Antibodies) signaling pathway.

  6. actin dynamics regulates the membrane motility of Kv1.3 channels.

  7. The increment and decrement of the basic residue number in a positively charged S4 sensor of Kv1.3 channel yields conductance-voltage relationship curves in the positive direction by approximately 31.2 mV and 2-4 mV

  8. the association between Kv1.3 and the COPII cargo adaptor subunit isoform Sec24a (show SEC24A Antibodies)

  9. Findings reveal that alpha-defensins are endogenous inhibitors of potassium voltage-gated channel subfamily A member 3 (Kv1.3) with distinct interaction mechanisms.

  10. JAK2 (show JAK2 Antibodies) participates in the signalling, regulating the voltage-gated K(+) channel (show KCND3 Antibodies) KCNA3.

Mouse (Murine) Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 3 (KCNA3) interaction partners

  1. Changes in Kv1.3 subcellular distribution upon EGFR (show EGFR Antibodies) activation were due to Kv1.3 clathrin-dependent endocytosis, which targets the Kv1.3 channels to the lysosomal degradative pathway.

  2. Kv1.3 channel serves as a negative regulator of phagocytosis in macrophages and can be a potential target in the treatment of macrophage dysfunction

  3. concluded that Kv1.3 may stimulate macrophage migration through the activation of ERK (show EPHB2 Antibodies).

  4. A compensatory upregulation of the potassium channels K2P3.1 (show KCNK3 Antibodies) and KV1.3 seems to counterbalance the deletion of K2P5.1 (show KCNK5 Antibodies).

  5. JAK2 (show JAK2 Antibodies) participates in the signalling, regulating the voltage-gated K(+) channel (show KCND3 Antibodies) KCNA3.

  6. Antigenic Stimulation of Kv1.3-Deficient Th Cells Gives Rise to a Population of Foxp3 (show FOXP3 Antibodies)-Independent T Cells with Suppressive Properties

  7. A potent and selective peptide blocker of the Kv1.3 channel: prediction from free-energy simulations and experimental confirmation

  8. Inhibition of NMDAR (show GRIN1 Antibodies) antagonists on the conductivity of Kv1.3 and KCa3.1 (show KCNN4 Antibodies) potassium channels was found.

  9. A significant increase of Kv1.3 protein levels was observed after LPS (show TLR4 Antibodies) challenge, an effect that was blunted by e-LXA4. Kv1.3 is required for the attenuation of NF-kappaB (show NFKB1 Antibodies) activity.

  10. Results indicate the potential use of Kv1.3 blockers for the treatment of obesity and insulin (show INS Antibodies) resistance.

KCNA3 Antigen Profile

Protein Summary

Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class, members of which allow nerve cells to efficiently repolarize following an action potential. It plays an essential role in T-cell proliferation and activation. This gene appears to be intronless and it is clustered together with KCNA2 and KCNA10 genes on chromosome 1.

Gene names and symbols associated with KCNA3

  • potassium voltage-gated channel, shaker-related subfamily, member 3 (KCNA3) antibody
  • potassium voltage-gated channel, shaker-related subfamily, member 3 (kcna3) antibody
  • potassium voltage-gated channel, shaker-related subfamily, member 3 (Kcna3) antibody
  • cKv1.1 antibody
  • HGK5 antibody
  • HLK3 antibody
  • HPCN3 antibody
  • HUKIII antibody
  • Kca1-3 antibody
  • kcna3b-a antibody
  • Kv1.3 antibody
  • Kv1.3-glyb antibody
  • Kv1.3B antibody
  • Mk-3 antibody
  • MK3 antibody
  • PCN3 antibody

Protein level used designations for KCNA3

glibenclamide-sensitive voltage-gated potassium channel , potassium voltage-gated channel subfamily A member 3 , potassium voltage-gated channel, shaker-related subfamily, member 3 , shaker-like potassium channel subunit Kv1.3B , potassium channel 3 , type n potassium channel , voltage-gated K(+) channel HuKIII , voltage-gated potassium channel protein Kv1.3 , voltage-gated potassium channel subunit Kv1.3 , MK3 , Voltage-gated potassium channel protein Kv1.3 (RGK5) (RCK3) (KV3) , potassium voltage gated channel, shaker related subfamily, member 3 , KV3 , RCK3 , RGK5 , voltage-gated potassium channel subunit Kv3 , Shaker-like voltage-gated potassium channel cKv1.1 , shaker subfamily potassium channel Kv1.3 alpha subunit , voltage-gated Kv1.3 potassium channel

GENE ID SPECIES
100328945 Oryctolagus cuniculus
373847 Xenopus laevis
3738 Homo sapiens
16491 Mus musculus
29731 Rattus norvegicus
404303 Gallus gallus
525507 Bos taurus
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