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anti-Pre-B-Cell Leukemia Homeobox Protein 1 (PBX1) Antibodies

PBX1 encodes a nuclear protein that belongs to the PBX homeobox family of transcriptional factors. Additionally we are shipping PBX1 Proteins (6) and PBX1 Kits (2) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PBX1 18514 P41778
PBX1 5087 P40424
PBX1 304947  
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Top anti-PBX1 Antibodies at antibodies-online.com

Showing 10 out of 67 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-PBX1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Jurkat cell lysate WB Suggested Anti-PBX1  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500  Positive Control: Jurkat cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Dog Goat Un-conjugated EIA, WB Western blot analysis: PBX1 antibody staining of K562 lysate at 0.5 µg/ml (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Mouse Un-conjugated FACS, IF, WB HEK293T cells transfected with either RC210944 overexpress plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-PBX1 antibody (ABIN2454629), and then analyzed by flow cytometry. Anti-PBX1 mouse monoclonal antibody (ABIN2454629) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY PBX1 (RC210944). 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Mouse Un-conjugated IF, WB Anti-PBX1 mouse monoclonal antibody (ABIN2454604) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY PBX1 (RC210944). HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PBX1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-PBX1. 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Mouse Un-conjugated IF, IHC (p), ELISA, WB Immunoperoxidase of monoclonal antibody to PBX1 on formalin-fixed paraffin-embedded human salivary gland. [antibody concentration 3 ug/ml] Immunofluorescence of monoclonal antibody to PBX1 on HeLa cell. [antibody concentration 10 ug/ml] 100 μg Log in to see 9 Days
$430.00
Details
Human Mouse Un-conjugated FACS, IF, IHC, WB Anti-PBX1 mouse monoclonal antibody (ABIN2454692) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY PBX1 (RC210944). HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PBX1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-PBX1. 100 μL Log in to see 2 to 3 Days
$482.90
Details
Human Rabbit Un-conjugated ICC, IF ICC/IF Image PBX1 antibody [N2C3] detects PBX1 protein at nucleus and cytoplasm by immunofluorescent analysis. Sample: SK-N-AS cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: PBX1 protein stained by PBX1 antibody [N2C3] , diluted at 1:500. Blue: Hoechst 33342 staining. 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Dog Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details

PBX1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine)
,

Human , , , ,
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Rat (Rattus)
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Top referenced anti-PBX1 Antibodies

  1. Human Monoclonal PBX1 Primary Antibody for IF, IHC (p) - ABIN562114 : Cheung, Chan, Chan, Ikegawa, Kou, Ngai, Smith, Luk, Huang, Mori, Sham, Kung: Pre-B-cell leukemia homeobox 1 (PBX1) shows functional and possible genetic association with bone mineral density variation. in Human molecular genetics 2009 (PubMed)
    Show all 3 references for ABIN562114

  2. Dog (Canine) Polyclonal PBX1 Primary Antibody for EIA, WB - ABIN498074 : Horman, Velu, Chaubey, Bourdeau, Zhu, Paul, Gebelein, Grimes: Gfi1 integrates progenitor versus granulocytic transcriptional programming. in Blood 2009 (PubMed)

  3. Chicken Polyclonal PBX1 Primary Antibody for WB - ABIN2777186 : Wang, Chu, Wang, Zhang, Elbein: Evaluation of sequence variants in the pre-B cell leukemia transcription factor 1 gene: a positional and functional candidate for type 2 diabetes and impaired insulin secretion. in Molecular genetics and metabolism 2005 (PubMed)

More Antibodies against PBX1 Interaction Partners

Mouse (Murine) Pre-B-Cell Leukemia Homeobox Protein 1 (PBX1) interaction partners

  1. Thus, PTBP1 (show PTBP1 Antibodies) controls the activity of Pbx1 to suppress its neuronal transcriptional program prior to induction of neuronal progenitor cells development.

  2. this study showed that the lupus susceptibility gene Pbx1 not only contributes to autoimmune pathology by impairing T cell tolerance, but also impairs the function of mesenchymal stem cells, which may also contribute to the disease directly or indirectly.

  3. Pbx1-dependent control of VMC (show PLXNA3 Antibodies) differentiation kinetics underlies gross renal vascular patterning.

  4. Results thus show how Pbx1 controls Fgf10 (show FGF10 Antibodies) in the developing lung.

  5. Prep1 and Meis1 (show MEIS1 Antibodies) competition for Pbx1 binding regulates protein stability and tumorigenesis.

  6. These results demonstrate a role for Pbx1 in restraining myeloid maturation while maintaining lymphoid potential to appropriately regulate progenitor reservoirs.

  7. The Systemic Lupus Erythematosus-associated Pbx1-d isoform acts as a dominant-negative transcriptional regulator.

  8. Data have demonstrated the presence of Meis, Pbx, and Prep proteins during early lineage segregation in mammals: Meis1, Meis3, Pbx1, Pbx2, Pbx3, and Prep1 in the mouse.

  9. In Pbx1-deficient dopaminergic neurons, the high affinity netrin-1 (show NTN1 Antibodies) receptor, deleted in colon cancer, is down-regulated.

  10. Data suggest that PBX1 regulates adipocyte development at multiple levels, promoting the generation of NC-derived APs (show SH2B2 Antibodies) during embryogenesis, while favoring APs (show SH2B2 Antibodies) proliferation and preventing their commitment to the adipocyte lineage in postnatal life.

Human Pre-B-Cell Leukemia Homeobox Protein 1 (PBX1) interaction partners

  1. Data identifies PBX1 amplification as a functional hallmark of aggressive ERalpha (show ESR1 Antibodies)-positive breast cancers.

  2. We observed significant enrichment of the neuroactive ligand-receptor interaction pathway in TCF3 (show TCF3 Antibodies)-PBX1 as well as an enrichment of genes involved in immunity and infection pathways in ETV6 (show ETV6 Antibodies)-RUNX1 (show RUNX1 Antibodies) subtype

  3. This association study successfully identified two susceptibility Single Nucleotide Polymorphisms, (WNT9B (show WNT9B Antibodies) and PBX1) associated with Mayer-Rokitansky-Kuster-Hauser syndrome risk, both separately and interactively.

  4. PBX1 promotes frontal cortex patterning by repressing genes that promote dorsocaudal fate.

  5. When intensive chemotherapy was used, the TCF3 (show TCF3 Antibodies)-PBX1 was associated with a favorable outcome in childhood pre-B ALL.

  6. Induction of PBX1 expression was associated with 13-cisRA responsiveness in neuroblastoma (show ARHGEF16 Antibodies).

  7. In this study, we showed that TCF3 (show TCF3 Antibodies)-PBX1 positive pediatric BCP (show OPN1SW Antibodies)-ALL patients treated according to the JACLS ALL02 and CCLSG ALL2004 protocol had favorable outcomes

  8. E2A (show TCF3 Antibodies)-PBX1 fusion gene caused by t(1;19)(q23;p13) may be a common genetic change in AIS (show AR Antibodies) and a survival determinant for female AIS (show AR Antibodies) patients at early stage.

  9. Data indicate that among 31 thymus development-related genes, PBX1 copy number gain and FOXC1 (show FOXC1 Antibodies) copy number loss were presented in 43.0% and 39.5% of the tumors, respectively.

  10. E2a (show TCF3 Antibodies)-pbx1-positive patients are associated with more aggressive acute lymphoblastic leukemia.

Xenopus laevis Pre-B-Cell Leukemia Homeobox Protein 1 (PBX1) interaction partners

  1. These overall data suggest that ZFPIP and Pbx1 could be partners and cooperate in the regulation of essential neural genes during Xenopus development.

PBX1 Antigen Profile

Protein Summary

This gene encodes a nuclear protein that belongs to the PBX homeobox family of transcriptional factors. Studies in mice suggest that this gene may be involved in the regulation of osteogenesis, and required for skeletal patterning and programming. A chromosomal translocation, t(1\;19) involving this gene and TCF3/E2A gene, is associated with pre-B-cell acute lymphoblastic leukemia. The resulting fusion protein, in which the DNA binding domain of E2A is replaced by the DNA binding domain of this protein, transforms cells by constitutively activating transcription of genes regulated by the PBX protein family. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with PBX1

  • pre B cell leukemia homeobox 1 (Pbx1) antibody
  • pre-B-cell leukemia homeobox 1 (PBX1) antibody
  • pre-B-cell leukemia homeobox 1 (Pbx1) antibody
  • pre-B-cell leukemia homeobox 1 (pbx1) antibody
  • 2310056B04Rik antibody
  • AI848790 antibody
  • AU015730 antibody
  • D230003C07Rik antibody
  • Pbx-1 antibody
  • PBX1A antibody
  • pbx1b antibody
  • Xpbx1 antibody
  • Xpbx1b antibody

Protein level used designations for PBX1

homeobox protein PBX1 , pre B-cell leukemia transcription factor 1 , pre-B-cell leukemia transcription factor 1 , homeobox protein PRL , Homeobox protein pbx1 , pre-B-cell leukemia transcription factor 1b

GENE ID SPECIES
18514 Mus musculus
395505 Gallus gallus
5087 Homo sapiens
488669 Canis lupus familiaris
304947 Rattus norvegicus
399184 Xenopus laevis
540688 Bos taurus
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