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anti-Prenyl (Decaprenyl) Diphosphate Synthase, Subunit 2 (PDSS2) Antibodies

The protein encoded by PDSS2 is an enzyme that synthesizes the prenyl side-chain of coenzyme Q, or ubiquinone, one of the key elements in the respiratory chain. Additionally we are shipping PDSS2 Proteins (5) and PDSS2 Kits (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PDSS2 57107 Q86YH6
PDSS2 365592 Q5U2R1
PDSS2 71365 Q33DR3
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Top anti-PDSS2 Antibodies at antibodies-online.com

Showing 10 out of 73 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated FACS, IHC, WB HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PDSS2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-PDSS2. Flow cytometric Analysis of Hela cells, using anti-PDSS2 antibody (ABIN2455301), (Red), compared to a nonspecific negative control antibody, (Blue). 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Mouse Un-conjugated IHC, WB HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PDSS2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-PDSS2. Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-PDSS2 mouse monoclonal antibody. (ABIN2455331) 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Mouse Un-conjugated IF, IHC, WB Anti-PDSS2 mouse monoclonal antibody (ABIN2455335) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY PDSS2 (RC207892). HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PDSS2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-PDSS2. 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Mouse Un-conjugated IF, WB Anti-PDSS2 mouse monoclonal antibody (ABIN2455333) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY PDSS2 (RC207892). HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PDSS2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-PDSS2. 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Mouse Un-conjugated FACS, IHC, WB HEK293T cells transfected with either RC207892 overexpress plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-PDSS2 antibody (ABIN2455313), and then analyzed by flow cytometry. HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PDSS2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-PDSS2. 100 μL Log in to see 2 to 3 Days
$482.90
Details
Human Rabbit Un-conjugated WB WB Image Sample (50 ug of whole cell lysate) A: Mouse brain 10% SDS PAGE antibody diluted at 1:1000 WB Image Sample (30 ug of whole cell lysate) A: A431 , 10% SDS PAGE antibody diluted at 1:1000 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Mouse Un-conjugated IHC (p), WB 100 μL Log in to see 8 to 10 Days
$493.17
Details
Human Mouse Un-conjugated FACS, IHC (p), WB 100 μL Log in to see 8 to 10 Days
$493.17
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Rat brain lysate probed with Anti PDSS2 Polyclonal Antibody, Unconjugated (ABIN1386354) at 1:200 in 4 °C. Followed by conjugation to secondary antibody at 1:3000 90min in 37 °C. Predicted band 44D. Observed band size: 44kD Formalin-fixed and paraffin embedded human kidney labeled with Anti-PDSS2 Polyclonal Antibody, Unconjugated (ABIN1386354) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$269.50
Details

PDSS2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-PDSS2 Antibodies

  1. Cow (Bovine) Polyclonal PDSS2 Primary Antibody for WB - ABIN2783534 : Diomedi-Camassei, Di Giandomenico, Santorelli, Caridi, Piemonte, Montini, Ghiggeri, Murer, Barisoni, Pastore, Muda, Valente, Bertini, Emma: COQ2 nephropathy: a newly described inherited mitochondriopathy with primary renal involvement. in Journal of the American Society of Nephrology : JASN 2007 (PubMed)

More Antibodies against PDSS2 Interaction Partners

Human Prenyl (Decaprenyl) Diphosphate Synthase, Subunit 2 (PDSS2) interaction partners

  1. PDSS2 encodes a putative tumor suppressor, and its expression is regulated by hypermethylation of its promoter in gastric cancer cells.

  2. Decreased PDSS2 expression is an unfavorable prognostic factor for hepatocellular carcinoma, and PDSS2 has potent anticancer activity in HCC (show FAM126A Antibodies) tissues and HepG2 cells.

  3. Decreased PDSS2 mRNA levels were detected in HCC (show FAM126A Antibodies) tissues of 56 patients, correlated with shorter disease-specific survival, and was identified as an independent prognostic factor

  4. PDSS2 has tumor-suppressing activity in human lung cancer cells by enhancing apoptosis and inhibiting tumorigenic capacity.

  5. Human PDSS2 polymorphisms are associated with podocyte diseases. A deficiency of coenzyme Q10 (show EIF2C2 Antibodies) is manifested in lymphoblastoid cell lines derived from focal segmental glomerulosclerosis patients.

  6. Loss of PDSS2 expression is associated with non-small cell lung cancer.

  7. Data show that expression of either dlp1 or dps1 recovered the thermo-sensitive growth of an E. coli ispB(R321A) mutant and restored IspB activity and production of Coenzyme Q-8.

  8. murine and human solanesyl and decaprenyl diphosphate synthases are heterotetramers composed of newly characterized hDPS1 (show PDSS1 Antibodies) (mSPS1 (show PDSS1 Antibodies)) and hDLP1 (mDLP1).

  9. Expression of PDSS2 is downregulated in human gastric cancer. PDSS2 may be a potent gastric cancer growth suppressor in vitro acting through apoptosis pathways.

Mouse (Murine) Prenyl (Decaprenyl) Diphosphate Synthase, Subunit 2 (PDSS2) interaction partners

  1. kidney-specific loss of mitochondria triggered by oxidative stress may be the cause of renal failure in Pdss2(kd/kd) mice

  2. During cerebellum development, Pdss2 knockout results in severe cerebellum hypoplasia by impairing cell migration and eliciting ectopic apoptosis, whereas Pdss2 knockout in Purkinje cells at postnatal stages leads to the development of cerebellar ataxia (show USP14 Antibodies).

  3. Data show that focal segmental glomerulopathy-like kidney disease in Pdss2 mutant animals with primary coenzyme Q (CoQ) deficiency is significantly ameliorated by oral treatment with probucol.

  4. kd is mutant allele of novel gene for prenyltransferase-like mitochondrial protein (PLMP). Alternatively spliced. Larger gene product has one domain resembling transprenyltransferase and another similar to geranylgeranyl pyrophosphate synthase (show GGPS1 Antibodies). (PLMP)

  5. murine and human solanesyl and decaprenyl diphosphate synthases are heterotetramers composed of newly characterized hDPS1 (show PDSS1 Antibodies) (mSPS1 (show PDSS1 Antibodies)) and hDLP1 (mDLP1 (show PDSS1 Antibodies)).

  6. a presumed autoimmune kidney disease in mice with the missense Pdss2(kd/kd) genotype can be attributed to a mitochondrial CoQ biosynthetic defect

  7. Dietary supplementation with coenzyme Q10 provides a dramatic rescue of both proteinuria and interstitial nephritis in the Pdss2kd/kd mutant mice.

PDSS2 Antigen Profile

Protein Summary

The protein encoded by this gene is an enzyme that synthesizes the prenyl side-chain of coenzyme Q, or ubiquinone, one of the key elements in the respiratory chain. The gene product catalyzes the formation of all trans-polyprenyl pyrophosphates from isopentyl diphosphate in the assembly of polyisoprenoid side chains, the first step in coenzyme Q biosynthesis. Defects in this gene are a cause of coenzyme Q10 deficiency.

Gene names and symbols associated with PDSS2

  • prenyl (decaprenyl) diphosphate synthase, subunit 2 (PDSS2) antibody
  • prenyl (decaprenyl) diphosphate synthase, subunit 2 (pdss2) antibody
  • decaprenyl-diphosphate synthase subunit 2 (CpipJ_CPIJ016311) antibody
  • decaprenyl-diphosphate synthase subunit 2 (SJAG_01865) antibody
  • decaprenyl-diphosphate synthase subunit 2 (Tsp_08290) antibody
  • prenyl (decaprenyl) diphosphate synthase, subunit 2 (Pdss2) antibody
  • prenyl (solanesyl) diphosphate synthase, subunit 2 (Pdss2) antibody
  • 5430420P03Rik antibody
  • bA59I9.3 antibody
  • C6orf210 antibody
  • COQ10D3 antibody
  • DLP1 antibody
  • Gm60 antibody
  • hDLP1 antibody
  • kd antibody
  • mDLP1 antibody
  • Plmp antibody
  • zgc:92156 antibody

Protein level used designations for PDSS2

prenyl (decaprenyl) diphosphate synthase, subunit 2 , prenyl diphosphate synthase, subunit 2 , decaprenyl-diphosphate synthase subunit 2 , decaprenyl-diphosphate synthase subunit 2-like , all-trans-decaprenyl-diphosphate synthase subunit 2 , decaprenyl pyrophosphate synthase subunit 2 , decaprenyl pyrophosphate synthetase subunit 2 , subunit 2 of decaprenyl diphosphate synthase , prenyl (decaprenyl) diphosphate synthase subunit 2 , prenyl (solanesyl) diphosphate synthase, subunit 2 , prenyltransferase-like mitochondrial protein , solanesyl-diphosphate synthase subunit 2

GENE ID SPECIES
100072062 Equus caballus
421777 Gallus gallus
462912 Pan troglodytes
493532 Xenopus (Silurana) tropicalis
6049785 Culex quinquefasciatus
7048046 Schizosaccharomyces japonicus yFS275
10905715 Trichinella spiralis
100405832 Callithrix jacchus
57107 Homo sapiens
436624 Danio rerio
100312977 Sus scrofa
521115 Bos taurus
365592 Rattus norvegicus
481950 Canis lupus familiaris
71365 Mus musculus
Selected quality suppliers for anti-PDSS2 (PDSS2) Antibodies
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