anti-Procollagen-Lysine 2-Oxoglutarate 5-Dioxygenase 2 (PLOD2) Antibodies

The protein encoded by PLOD2 is a membrane-bound homodimeric enzyme that is localized to the cisternae of the rough endoplasmic reticulum. Additionally we are shipping PLOD2 Proteins (7) and PLOD2 Kits (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PLOD2 26432 Q9R0B9
PLOD2 300901  
PLOD2 5352 O00469
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Top anti-PLOD2 Antibodies at antibodies-online.com

Showing 10 out of 40 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated IHC, WB <b>WB Suggested Anti-PLOD2 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>DU145 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB PLOD2 antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 2 to 3 Days
$510.36
Details
Cow Rabbit Un-conjugated IHC (p), WB Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 7 to 9 Days
$676.50
Details
Human Rabbit Un-conjugated WB PLOD2 Antibody (C-term) (ABIN1881661) western blot analysis in Hela cell line lysates (35 µg/lane). This demonstrates the PLOD2 antibody detected the PLOD2 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated IHC (p), WB   100 μL Log in to see 7 to 9 Days
$493.17
Details
Human Mouse Un-conjugated WB   100 μL Log in to see 7 to 9 Days
$493.17
Details
Human Rabbit Un-conjugated IF, IHC, WB Immunofluorescence analysis of U20S cell using PLOD2 antibody. Blue: DAPI for nuclear staining. 100 μL Log in to see 16 Days
$323.13
Details
Human Rabbit Un-conjugated IF, IP, WB PLOD2 MaxPab rabbit polyclonal antibody. Western Blot analysis of PLOD2 expression in HeLa. PLOD2 MaxPab rabbit polyclonal antibody. Western Blot analysis of PLOD2 expression in mouse liver. 100 μL Log in to see 11 to 12 Days
$418.57
Details
Human Mouse Un-conjugated IHC, IHC (p), WB Immunohistochemistry-Paraffin: Lysine Hydroxylase 2/PLOD2 Antibody (6D1) [NBP2-46451] - Analysis of Adenocarcinoma of Human colon tissue. Immunohistochemistry-Paraffin: Lysine Hydroxylase 2/PLOD2 Antibody (6D1) [NBP2-46451] - Analysis of Human prostate tissue. 0.1 mL Log in to see 8 to 11 Days
$447.56
Details
Human Rabbit Un-conjugated WB   100 μL Log in to see 2 to 3 Days
$289.00
Details

PLOD2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Mouse (Murine)


Rat (Rattus)


Human
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,

Top referenced anti-PLOD2 Antibodies

  1. Cow (Bovine) Polyclonal PLOD2 Primary Antibody for IHC, WB - ABIN2775556 : Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: Large-scale mapping of human protein-protein interactions by mass spectrometry. ... in Molecular systems biology 2007 (PubMed)

More Antibodies against PLOD2 Interaction Partners

Mouse (Murine) Procollagen-Lysine 2-Oxoglutarate 5-Dioxygenase 2 (PLOD2) interaction partners

  1. The finding that LH2 modifies collagen in the extracellular space challenges the current view that LH2 functions solely on the endoplasmic reticulum and could also have important implications for cancer biology.

  2. Authors propose that lysyl hydroxylase 2, and the subsequent increase in pyridinoline cross-links, is responsible for the persistent fibrosis in experimental osteoarthritis.

  3. Lysyl hydroxylase-2b directs collagen cross-linking pathways through its action on telopeptidyl lysine residues.

  4. LH2b (show LHX9 Antibodies) catalyzes post-translational modification of collagen in collagen matrix formation and mineralization in bone.

  5. analysis of the specific regulation for the expression of LH isoforms as well as for alternative splicing of LH2 during embryogenesis and in different tissues

  6. TIA1 (show TIA1 Antibodies) and TIAL1 (show TIAL1 Antibodies) regulate the alternate splicing of lysyl hydroxylase 2

Human Procollagen-Lysine 2-Oxoglutarate 5-Dioxygenase 2 (PLOD2) interaction partners

  1. This study reports for the first time the expression of PLOD2 in Brain Arteriovenous Malformations and suggests a potential role of PLOD2 in brain Arteriovenous Malformations pathophysiology.

  2. FKBP65 (show FKBP10 Antibodies) is linked to pyridinoline cross-linking by specifically mediating the dimerization of LH2.

  3. PLOD2, which is associated with the stiffness of the extracellular matrix, was directly regulated by miR (show MLXIP Antibodies)-26a-5p and miR (show MLXIP Antibodies)-26b-5p and may be a good prognostic marker in patients with BC

  4. The finding that LH2 modifies collagen in the extracellular space challenges the current view that LH2 functions solely on the endoplasmic reticulum and could also have important implications for cancer biology.

  5. Results show that miR (show MLXIP Antibodies)-26a and miR (show MLXIP Antibodies)-26b were significantly downregulated in renal cell carcinoma (show MOK Antibodies) clinical specimens and appeared to function as tumor suppressors through regulation of collagen cross-linking enzymes, LOXL2 (show LOXL2 Antibodies) and PLOD2, both of which function as oncogenes in this disease.

  6. findings reveal that TGFbeta1 (show TGFB1 Antibodies) induces a SP1 (show PSG1 Antibodies)- and SMAD3 (show SMAD3 Antibodies)-dependent recruitment of histone modifying enzymes to the PLOD2 promoter other than the currently known TGFbeta1 (show TGFB1 Antibodies) downstream co-activators and epigenetic modifications

  7. LH2 enhances the metastatic properties of tumor cells and functions as a regulatory switch that controls the relative abundance of biochemically distinct types of collagen cross-links in the tumor stroma.

  8. TGFbeta (show TGFB1 Antibodies) induced PLOD2/LH2 expression in human synovial osteoarthritic fibroblasts through ALK5 (show TGFBR1 Antibodies) signaling.

  9. data indicate that HIF-1alpha (show HIF1A Antibodies) controls sarcoma metastasis through PLOD2-dependent collagen modification and organization in primary tumors

  10. Infrapatellar fat pad (show PADI4 Antibodies) contributeS to the development of synovial fibrosis in the knee joint by increasing collagen production, PLOD2 expression, cell proliferation, and cell migration.

PLOD2 Antigen Profile

Protein Summary

The protein encoded by this gene is a membrane-bound homodimeric enzyme that is localized to the cisternae of the rough endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VIB have deficiencies in lysyl hydroxylase activity. Mutations in the coding region of this gene are associated with Bruck syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene names and symbols associated with PLOD2

  • procollagen lysine, 2-oxoglutarate 5-dioxygenase 2 (Plod2) antibody
  • procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 (PLOD2) antibody
  • D530025C14Rik antibody
  • LH2 antibody
  • Plod-2 antibody
  • TLH antibody

Protein level used designations for PLOD2

lysyl hydroxylase 2 , procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 , LH2 , Procollagen-lysine 2-oxoglutarate 5-dioxygenase (Lysine hydroxylase) 2 , Procollagen-lysine, 2-oxoglutarate 5-dioxygenase (Lysine hydroxylase) 2 , lysine hydroxylase 2 , lysyl hydroxlase 2 , telopeptide lysyl hydroxylase , procollagen-lysine 2-oxoglutarate 5-dioxygenase 2

GENE ID SPECIES
26432 Mus musculus
300901 Rattus norvegicus
5352 Homo sapiens
641354 Sus scrofa
533642 Bos taurus
Selected quality suppliers for anti-PLOD2 (PLOD2) Antibodies
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