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May have a role in the regulation of spermatogenesis.. Additionally we are shipping PD-1 Antibodies (426) and PD-1 Kits (13) and many more products for this protein.
Showing 10 out of 71 products:
Human PD-1 Protein expressed in Wheat germ - ABIN1314407
Matsumoto, Miyake, Matsushita, Ohnishi, Ikeda, Shiraha, Takaki, Nouso, Yamamoto: Anti-programmed cell death-1 antibody as a new serological marker for type 1 autoimmune hepatitis. in Journal of gastroenterology and hepatology 2013
Show all 2 references for ABIN1314407
Mouse (Murine) PD-1 Protein expressed in Human Cells - ABIN2007359
Prodeus, Abdul-Wahid, Fischer, Huang, Cydzik, Gariépy: Targeting the PD-1/PD-L1 Immune Evasion Axis With DNA Aptamers as a Novel Therapeutic Strategy for the Treatment of Disseminated Cancers. in Molecular therapy. Nucleic acids 2015
Data suggest a reduction in the CD47 antigen (show CD47 Proteins)/signal-regulatory protein alpha (show SIRPA Proteins) (SIRPalpha) pathway by programmed cell death protein 1 (PD-1) blockade, which regulates Myeloid-derived suppressor cells (MDSCs) and tumor associated macrophages (TAMs).
Immune checkpoint inhibitors, particularly those targeting PD-1 and PD-L1 (show CD274 Proteins) are clinically active for the treatment of lung cancer and represent an exciting step forward in lung cancer therapy.
Pulmonary LELC have remarkably high incidence of PD-L1 (show CD274 Proteins) expression. PD-L1 (show CD274 Proteins) was a negative prognostic factor for DFS (show FST Proteins) in surgically resected pulmonary LELC.
High PD-1 expression is associated with brain metastases.
PD-1 regulates peripheral T-cell responses in both human and murine rheumatoid arthritis
PD-1 might be an independent, universal marker of CLL cells and a part of their activated phenotype, and subsequently might modulate the function of ZAP-70 (show ZAP70 Proteins).
expression of PD-1 identifies a diverse and patient-specific antitumor T cell response in peripheral blood, providing a novel noninvasive strategy to develop personalized therapies using neoantigen-reactive lymphocytes or TCRs to treat cancer
PDCD1 single nucleotide genes polymorphisms confer susceptibility to juvenile-onset systemic lupus erythematosus.
Data suggest signaling via CD279/PDCD1 and its ligand CD274/PD-L1 (show CD274 Proteins) is effective chemotherapy target in non-small cell lung cancer; PD-L1 (show CD274 Proteins) is best currently available immunohistochemistry biomarker for response to immune checkpoint inhibitors. [REVIEW]
After stimulation, a defect in T regulatory cell proliferation was observed in diabetics and the percentages of total PD-1, PD-1low and PD-1high expressing cells were lower in patients.
LAG3 (show LAG3 Proteins) and PD1 co-inhibitory molecules have roles in collaborating to limit CD8 (show CD8A Proteins)+ T cell signaling and dampen antitumor immunity in a murine ovarian cancer model
Decidual NK, NKT (show CTSL1 Proteins) and gamma/delta T cells showed increased PD-1 expression and reduced cytotoxic potential when compared to the periphery.
The endogenous PD-1/PD-L pathway does not limit acute experimental foreign antigen-induced circulating immune complex glomerulonephritis.
AE2 (show SLC4A2 Proteins) deficiency results in intrahepatic T-cell activation and PD-1/PD-L1 (show CD274 Proteins) mediated deletion, favoring autoimmune cholangitis.
Burkholderia pseudomallei appears to upregulate the expression of PD-1 on T cells to evade host immune responses, which likely facilitates bacterial persistence in the host.
increased programmed death-1 signaling pathway expression by conventional natural killer cells promotes host protection at the intestinal mucosa during acute infection with a bacterial gut (show GUSB Proteins) pathogen.
Poxvirus-Based Active Immunotherapy with PD-1 and LAG-3 (show LAG3 Proteins) Dual Immune Checkpoint Inhibition Overcomes Compensatory Immune Regulation, Yielding Complete Tumor Regression in Mice.
genetic mechanism of tumor immune escape caused by structural variations commonly disrupting the 3' region of the PD-L1 (show CD274 Proteins) gene
The results demonstrated that blockade of PD-1/B7H1 (show CD274 Proteins) pathway could promote mouse NK cells to kill the GL261GSCs, and the PD-1-inhibited NK cells could be a feasible immune therapeutic approach against Glioblastoma multiforme.
May have a role in the regulation of spermatogenesis.
programmed cell death 1
, programmed cell death protein 1
, protein PD-1
, programmed death 1
, spermatogenesis associated PD1
, spermatogenesis-associated protein 2
, spermatogenesis-associated protein PD1