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Programmed Cell Death 1 Proteins (PDCD1)

May have a role in the regulation of spermatogenesis.. Additionally we are shipping PD-1 Antibodies (615) and PD-1 Kits (13) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PDCD1 5133 Q15116
PDCD1 18566 Q02242
PDCD1 301626  
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Top PD-1 Proteins at antibodies-online.com

Showing 10 out of 75 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Human Cells Mouse His tag,Fc Tag 100 μg Log in to see 16 Days
$250.80
Details
HOST_HEK-293 Cells Human His tag,Fc Tag,Biotin The purity of Biotinylated Human PD-1, His Tag & FC tag was determined by DTT-reduced (+) SDS-PAGE and staining overnight with Coomassie Blue. 5 μg Log in to see 2 to 3 Days
$236.25
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag 0.05 mg Log in to see 2 to 3 Days
$275.00
Details
HOST_Escherichia coli (E. coli) Human His-SUMO Tag 50 μg Log in to see 21 to 26 Days
$341.00
Details
HOST_HEK-293 Cells Mouse His tag 100 μg Log in to see 2 to 3 Days
$275.00
Details

PDCD1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , , , , , ,
, , , , , , , , , , , , , ,
Mouse (Murine) , , , , , ,
, , , , ,
Rat (Rattus) , ,
, ,

Top referenced PD-1 Proteins

  1. Human PD-1 Protein expressed in Wheat germ - ABIN1314407 : Matsumoto, Miyake, Matsushita, Ohnishi, Ikeda, Shiraha, Takaki, Nouso, Yamamoto: Anti-programmed cell death-1 antibody as a new serological marker for type 1 autoimmune hepatitis. in Journal of gastroenterology and hepatology 2013 (PubMed)
    Show all 2 references for ABIN1314407

  2. Mouse (Murine) PD-1 Protein expressed in Human Cells - ABIN2007359 : Prodeus, Abdul-Wahid, Fischer, Huang, Cydzik, Gariépy: Targeting the PD-1/PD-L1 Immune Evasion Axis With DNA Aptamers as a Novel Therapeutic Strategy for the Treatment of Disseminated Cancers. in Molecular therapy. Nucleic acids 2015 (PubMed)

More Proteins for Programmed Cell Death 1 (PDCD1) Interaction Partners

Human Programmed Cell Death 1 (PDCD1) interaction partners

  1. Study demonstrates that PD-1(+) TIMC and intratumoral PD-L1 (show CD274 Proteins)(+) expression did not significantly impact tumor aggressiveness or clinical outcome in non-ccRCC specimens.

  2. Immune surveillance is an important mechanism in prevention of cancer development and inhibition of growth of tumors and metastasis. Checkpoint pathways prevent immune response through multiple methods including CTLA-4 (show CTLA4 Proteins) and PD-1/PD-L1 (show CD274 Proteins) pathways.A variety of immune checkpoint inhibitors (PD-1/PD-L1 (show CD274 Proteins) and CTLA-4 (show CTLA4 Proteins) inhibitors) have been studied in recurrent and metastatic head and neck cancers with encouraging efficacy

  3. n combination with anti-PD-1/PD-L1 (show CD274 Proteins), the CTLA-4 (show CTLA4 Proteins)-expanded T cells are prevented from being functionally inhibited when they enter into the tumor microenvironment.

  4. The CTLA-4 (show CTLA4 Proteins) receptor was one of the first checkpoint inhibitors to be targeted with limited exploration and efficacy in sarcoma.The PD-1/PD-L1 (show CD274 Proteins) immunologic checkpoint pathway has demonstrated efficacy in many malignancies; studies are ongoing in sarcoma.

  5. PD-1 expression is associated with a poor prognosis in gastric cancer after curative resection.

  6. Data suggest that PD-1/PDCD1 (programmed cell death protein 1) and Tim-3/HAVCR2 (hepatitis A virus cellular receptor 2 (show HAVCR2 Proteins)) operate within the functional immune-modulatory network to promote Th2-(type-2 helper T cell-)mediated immunity at the maternal-fetal interface.

  7. High PD-1 expression is Correlated with Non-Small Cell Lung Cancer.

  8. findings support the use of Tim-3 (show HAVCR2 Proteins)-Tim-3L blockade together with PD-1-PD-L1 (show CD274 Proteins) blockade to reverse tumor-induced T-cell exhaustion/dysfunction in patients with colorectal cancer.

  9. Report increased expression of PD-1 in individuals that had recently been treated for tuberculosis, and a small increase in PD-1-expression in active TB disease.

  10. PD-1 and CTLA-4 (show CTLA4 Proteins) expression during the symptomatic phase was significantly higher in the T-cells of Acute Hepatitis A patients than in those of Acute Toxic Hepatitis patients or healthy controls.

Mouse (Murine) Programmed Cell Death 1 (PDCD1) interaction partners

  1. Tim-3 (show HAVCR2 Proteins)(+) PD-1(+) CD8 (show CD8A Proteins)(+) T cells showed more evident properties associated with exhaustion than Tim-3 (show HAVCR2 Proteins)(-) PD-1(+) CD8 (show CD8A Proteins)(+) T cells.

  2. that porcine islet-specific tolerance is dependent on PD-1, which could not be extended to skin grafts

  3. Programmed cell death-1 engagement followed by zymosan stimulation might primarily attenuate the phosphorylation of tyrosine residue in Programmed cell death-1 receptor/ligand.

  4. Study suggests that expression of the inhibitory receptors PD-1 and LAG-3 (show LAG3 Proteins) on CD4 (show CD4 Proteins)(+) T cells and their reduced IL-2 (show IL2 Proteins) production are common characteristic features of Plasmodium infection.

  5. these data suggest a scenario in which microglia are involved in the regulation of experimental autoimmune encephalomyelitis by suppressing Th1 (show HAND1 Proteins)-cell differentiation via the PD-L1 (show CD274 Proteins)-nitric oxide pathway.

  6. Blockade of TGFbeta (show TGFB1 Proteins) downregulated PD-1 and PD-L1 (show CD274 Proteins) expression and precipitated graft rejection.

  7. PD-1 regulates peripheral T-cell responses in both human and murine rheumatoid arthritis

  8. LAG3 (show LAG3 Proteins) and PD1 co-inhibitory molecules have roles in collaborating to limit CD8 (show CD8A Proteins)+ T cell signaling and dampen antitumor immunity in a murine ovarian cancer model

  9. Decidual NK, NKT (show CTSL1 Proteins) and gamma/delta T cells showed increased PD-1 expression and reduced cytotoxic potential when compared to the periphery.

  10. The endogenous PD-1/PD-L pathway does not limit acute experimental foreign antigen-induced circulating immune complex glomerulonephritis.

PD-1 (PDCD1) Protein Profile

Protein Summary

May have a role in the regulation of spermatogenesis.

Gene names and symbols associated with PDCD1

  • programmed cell death 1 (PDCD1)
  • programmed cell death 1 (Pdcd1)
  • spermatogenesis associated 2 (SPATA2)
  • CD279 protein
  • hPD-1 protein
  • hPD-l protein
  • Ly101 protein
  • PD-1 protein
  • PD1 protein
  • Pdc1 protein
  • SLEB2 protein
  • tamo protein

Protein level used designations for PDCD1

programmed cell death 1 , programmed cell death protein 1 , protein PD-1 , programmed death 1 , mPD-1 , spermatogenesis associated PD1 , spermatogenesis-associated protein 2 , spermatogenesis-associated protein PD1

GENE ID SPECIES
424913 Gallus gallus
5133 Homo sapiens
486213 Canis lupus familiaris
613842 Bos taurus
18566 Mus musculus
301626 Rattus norvegicus
9825 Homo sapiens
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