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Negatively regulates TSP1 expression at the level of transcription. Additionally we are shipping Proline Rich 13 Antibodies (14) and many more products for this protein.
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High Txr1 expression is associated with oxaliplatin resistance in gastric cancer.
Low TXR1 mRNA levels were associated with higher response rate (RR), longer median progression-free survival (PFS) and median overall survival (mOS (show MOS Proteins)), whereas high TSP1 (show THBS1 Proteins) expression was correlated with higher RR, longer PFS and mOS (show MOS Proteins)
Multivariate analysis showed that high TXR1/low TSP1 (show THBS1 Proteins) expression was an independent prognostic factor for decreased median time to tumor progression (TTP (show ADAMTS13 Proteins)) and median overall survival (mOS (show MOS Proteins)).
Negatively regulates TSP1 expression at the level of transcription. This down-regulation was shown to reduce taxane- induced apoptosis (By similarity).
proline-rich protein 13
, proline rich 13
, taxane-resistance protein