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Protein Arginine Methyltransferase 6 Proteins (PRMT6)

The protein encoded by PRMT6 belongs to the arginine N-methyltransferase family, which catalyze the sequential transfer of methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins, to form methylated arginine derivatives and S-adenosyl-L-homocysteine. Additionally we are shipping Protein Arginine Methyltransferase 6 Antibodies (82) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PRMT6 55170 Q96LA8
Rat PRMT6 PRMT6 295384  
PRMT6 99890 Q6NZB1
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Top Protein Arginine Methyltransferase 6 Proteins at antibodies-online.com

Showing 9 out of 11 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Human Cells Human His tag,DYKDDDDK Tag 50 μg Log in to see 16 Days
$382.80
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Xenopus tropicalis His tag   1 mg Log in to see 56 to 66 Days
$2,920.50
Details
Yeast Zebrafish His tag   1 mg Log in to see 56 to 66 Days
$2,948.00
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$3,030.50
Details
HOST_Baculovirus Human DYKDDDDK Tag PRMT6 activity assay. HMT assay measuring the activity of Recombinant PRMT6. Activity was detected by fluorography. Recombinant PRMT6 protein gel. PRMT6 protein was run on a 10% SDS-PAGE gel and stained with Coomassie blue. 20 μg Log in to see 1 to 2 Days
$484.17
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

PRMT6 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , ,
, , ,
Mouse (Murine)

Top referenced Protein Arginine Methyltransferase 6 Proteins

  1. Human PRMT6 Protein expressed in Human Cells - ABIN2004214 : Hyllus, Stein, Schnabel, Schiltz, Imhof, Dou, Hsieh, Bauer: PRMT6-mediated methylation of R2 in histone H3 antagonizes H3 K4 trimethylation. in Genes & development 2007 (PubMed)
    Show all 4 references for ABIN2004214

More Proteins for Protein Arginine Methyltransferase 6 (PRMT6) Interaction Partners

Human Protein Arginine Methyltransferase 6 (PRMT6) interaction partners

  1. PRMT6, which was down-regulated by androgen receptors and influenced cell migration and apoptosis of germ cells, could play a potentially important role in spermatogenesis.

  2. PRMT6 methylates tumor cell p21 (show CDKN1A Proteins) at arginine 156 and promotes phosphorylation of threonine 145 on p21 (show CDKN1A Proteins), increasing the cytoplasmic localization of p21 (show CDKN1A Proteins) and inducing resistance to anticancer drugs.

  3. PRMT6 influences PRC-mediated gene silencing at the rostral HOXA genes locus.

  4. Data show that HIV-1 Tat (show TAT Proteins) methylation by protein arginine methyltransferase 6 (PRMT6) can inhibit nucleolar retention.

  5. N terminus is methylated by PRMT6 and that this critically affects the functions of pUL69 for efficient mRNA export and replication of human cytomegalovirus.

  6. TBL1 (show TBL1X Proteins) is required to protect GPS2 (show GPS2 Proteins) from degradation, with methylation of GPS2 (show GPS2 Proteins) by arginine methyltransferase PRMT6 regulating the interaction with TBL1 (show TBL1X Proteins) and inhibiting proteasome-dependent degradation.

  7. PRMT6 mediates cigarette smoke extract induced apoptosis and inflammation through H3R2me2a in HUVECs.

  8. PRMT6 specifically interacts with ERalpha (show ESR1 Proteins) at its ligand-binding domain.

  9. Authors show that PRMT6 requires the activation domain, but surprisingly not the basic domain, of HIV-1 Tat (show TAT Proteins) for protein interaction.

  10. Data show arginine methyltransferase PRMT6 methylates the AT-hook motif of regulatory factor RFX5 (show RFX5 Proteins) and downregulates HLA-DQ expression.

Zebrafish Protein Arginine Methyltransferase 6 (PRMT6) interaction partners

  1. these results suggest that maternal Prmt6 is essential to early zebrafish development by directly repressing gadd45alphaa.

Mouse (Murine) Protein Arginine Methyltransferase 6 (PRMT6) interaction partners

  1. Six crystal structures of PRMT6 from Mus (show TRPV6 Proteins) musculus, solved and refined at 1.34 A for the highest resolution structure are described.

  2. Prmt6 is important for embryonic stem cell pluripotency and self-renewal.

  3. The findings define a new regulator of p53 (show TP53 Proteins) transcriptional regulation and define a role for PRMT6 and arginine methylation in cellular senescence.

Protein Arginine Methyltransferase 6 (PRMT6) Protein Profile

Protein Summary

The protein encoded by this gene belongs to the arginine N-methyltransferase family, which catalyze the sequential transfer of methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins, to form methylated arginine derivatives and S-adenosyl-L-homocysteine. This protein can catalyze both, the formation of omega-N monomethylarginine and asymmetrical dimethylarginine, with a strong preference for the latter. It specifically mediates the asymmetric dimethylation of Arg2 of histone H3, and the methylated form represents a specific tag for epigenetic transcriptional repression. This protein also forms a complex with, and methylates DNA polymerase beta, resulting in stimulation of polymerase activity by enhancing DNA binding and processivity.

Gene names and symbols associated with PRMT6

  • Arginine methyltransferase 6 (Art6)
  • protein arginine methyltransferase 6 (PRMT6)
  • protein arginine methyltransferase 6 (prmt6)
  • protein arginine N-methyltransferase 6 (PRMT6)
  • arginine N-methyltransferase, type I (PRMT6)
  • protein arginine methyltransferase 6 (Prmt6)
  • protein arginine N-methyltransferase 6 (Prmt6)
  • ARABIDOPSIS THALIANA PROTEIN ARGININE METHYLTRANSFERASE 6 protein
  • ATPRMT6 protein
  • AW124876 protein
  • BB233495 protein
  • CG9927 protein
  • DART6 protein
  • DKFZp459B1431 protein
  • Dmel\\CG9927 protein
  • hrmt1l6 protein
  • hrmt6 protein
  • im:6908706 protein
  • PRMT6 protein
  • protein arginine methyltransferase 6 protein

Protein level used designations for PRMT6

arginine methyltransferase 6 , CG9927-PA , Art6-PA , protein arginine methyltransferase 6 , HMT1 hnRNP methyltransferase-like 6 , Histone-arginine N-methyltransferase PRMT6 , protein arginine N-methyltransferase 6 , arginine N-methyltransferase, type I , heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 6 , histone-arginine N-methyltransferase PRMT6

GENE ID SPECIES
41699 Drosophila melanogaster
457073 Pan troglodytes
447344 Xenopus laevis
694284 Macaca mulatta
821541 Arabidopsis thaliana
5067888 Leishmania infantum JPCM5
100145123 Xenopus (Silurana) tropicalis
100172901 Pongo abelii
55170 Homo sapiens
295384 Rattus norvegicus
490133 Canis lupus familiaris
540228 Bos taurus
100156688 Sus scrofa
448867 Danio rerio
99890 Mus musculus
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