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The protein encoded by PDXK phosphorylates vitamin B6, a step required for the conversion of vitamin B6 to pyridoxal-5-phosphate, an important cofactor in intermediary metabolism. Additionally we are shipping Pyridoxal Kinase Antibodies (83) and Pyridoxal Kinase Proteins (26) and many more products for this protein.
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direct evidence that residue Trp (show TBPL1 ELISA Kits)(230) is crucial to maintain the structural and functional integrity of Bombyx mori pyridoxal kinase
This article describes how a cDNA encoding PLK (show PLK1 ELISA Kits) was cloned from Bombyx mori.
The pyridoxal kinase showed decreased levels and was highly carbonylated in the gene-on mice
This study identified a DNA variant (rs2010795) in PDXK associated with an increased risk of PD in the German cohort This association was confirmed in the British and Italian cohorts individually and reached a combined value.
Pyridoxal kinase expression was compared in fetal Down syndrome (DS) brain and controls; PDXK levels were found to be similar.
The crystal structure of the MgATP complex also reveals Mg(2 (show MUC7 ELISA Kits)+) and Na(+) acting in tandem to anchor the ATP at the active site of pyridoxal kinase.
It appears that specific interactions occur between PK and pyridoxal-5-phosphate-dependent enzymes, and the binding affinities of PK for PLP (show PLP1 ELISA Kits)-dependent enzymes decrease in the presence of PLP (show PLP1 ELISA Kits)
The phenotype, stress responses, vitamer levels, and regulation of the vitamin B6 pathway genes in Arabidopsis plants mutant in pyridoxine/pyridoxamine 5'-phosphate oxidase (show PNPO ELISA Kits) (PDX3) and SALT OVERLY SENSITIVE4 (SOS4) are reported.
The protein encoded by this gene phosphorylates vitamin B6, a step required for the conversion of vitamin B6 to pyridoxal-5-phosphate, an important cofactor in intermediary metabolism. The encoded protein is cytoplasmic and probably acts as a homodimer. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
, Pyridoxal kinase
, hypothetical protein
, pyridoxamine kinase
, pyridoxine kinase
, vitamin B6 kinase
, pyridoxal kinase (pyridoxine kinase)