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anti-Pyrimidinergic Receptor P2Y, G-Protein Coupled, 6 (P2RY6) Antibodies

The product of P2RY6 belongs to the family of P2 receptors, which is activated by extracellular nucleotides and subdivided into P2X ligand-gated ion channels and P2Y G-protein coupled receptors. Additionally we are shipping P2RY6 Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
P2RY6 5031 Q15077
P2RY6 233571 Q9ERK9
P2RY6 117264 Q63371
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Top anti-P2RY6 Antibodies at antibodies-online.com

Showing 10 out of 47 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of P2RY6 / P2Y2 Antibody (C-term) in 293 cell line lysates (35ug/lane). This demonstrates the P2RY6 antibody detected the P2RY6 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated WB Host: Rabbit  Target Name: P2RY6  Sample Tissue: MCF7 Whole Cell lysates  Antibody Dilution: 1.0 µg/mL P2RY6 is supported by BioGPS gene expression data to be expressed in MCF7 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IF, IHC (p) Staining of human placenta with ABIN121956 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated IHC (p) Staining of human placenta with ABIN121957 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated ICC, IHC (p) Anti-P2RY6 / P2Y6 antibody  ABIN1049221 IHC staining of human spleen, red pulp. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated IHC (p) Anti-P2RY6 / P2Y6 antibody  ABIN1049220 IHC staining of human spleen, red pulp. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated WB P2RY6 Antibody (C-term)  western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the P2RY6 antibody detected the P2RY6 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC, WB 100 μL Log in to see 14 Days
$369.79
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Cow Rabbit Un-conjugated IHC (p)   0.05 mL Log in to see 5 to 7 Days
$477.75
Details

P2RY6 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , , ,


, , , , ,
Mouse (Murine) ,


Rat (Rattus) ,


Top referenced anti-P2RY6 Antibodies

  1. Human Polyclonal P2RY6 Primary Antibody for EIA, WB - ABIN953969 : Hanna, Kruskal, Ezekowitz, Bloom, Collier: Role of macrophage oxidative burst in the action of anthrax lethal toxin. in Molecular medicine (Cambridge, Mass.) 1996 (PubMed)
    Show all 3 references for ABIN953969

More Antibodies against P2RY6 Interaction Partners

Human Pyrimidinergic Receptor P2Y, G-Protein Coupled, 6 (P2RY6) interaction partners

  1. data demonstrate that HNP-1 (show DEFA1 Antibodies) induces IL-8 (show IL8 Antibodies) production not only through P2Y6, but also through additional P2 receptors via an ERK1/2 (show MAPK1/3 Antibodies)-dependent mechanism in intestinal epithelial cells.

  2. nucleotides released during the airway inflammatory processes will activate P2Y6 receptors, which will lead to further release of inflammatory cytokines.

  3. high millimolar concentrations of ATP increased IL-8 (show IL8 Antibodies) and MCP-1 (show CCL2 Antibodies) release by the glioma cells stimulated with suboptimal LPS (show IRF6 Antibodies) concentration which were blocked by P2X7 (show P2RX7 Antibodies) and P2Y6 antagonists

  4. Data indicate that after P2Y6 receptor stimulation both phospholipase D (PLD (show PLD Antibodies)) and DGKzeta (show DGKZ Antibodies) enzymes are responsible for producing phosphatidic acid (PA).

  5. Using rat P2Y6 recombinant protein expressed in human astrocytoma cells, the authors found that the P2Y6 receptor is highly selective for UDP over UTP.

  6. Results indicate involvement of P2Y purinoceptors P2Y(1) and P2Y(6) receptors in ADP- and UDP-stimulated proliferation.

  7. no obvious correlation was found between the expression of P2Y6 and breast cancer cell proliferation

  8. Report role of ecto (show TRIM33 Antibodies)-NTPDases on UDP-sensitive P2Y (show P2RY1 Antibodies)(6) receptor activation during osteogenic differentiation of primary bone marrow stromal cells from postmenopausal women.

  9. P2Y (show P2RY1 Antibodies)(6) receptor signaling pathway may be a potential therapeutic target for MSU (show BCKDHA Antibodies)-associated inflammatory diseases, such as tophaceous gout.

  10. P2Y6 receptor transgene is an important endogenous inhibitor of T cell function in mice with allergic pulmonary inflammation

Mouse (Murine) Pyrimidinergic Receptor P2Y, G-Protein Coupled, 6 (P2RY6) interaction partners

  1. These results suggest that increased formation of AT1R (show AGTRAP Antibodies)-P2Y6R heterodimers with age may increase the likelihood of hypertension induced by Ang II (show AGT Antibodies).

  2. Study demonstrates that AgRP (show AGRP Antibodies) neurons express the purinergic receptor (show P2RX7 Antibodies) 6 (P2Y6), which is activated by uridine-diphosphate (UDP). In vivo, UDP induces ERK (show EPHB2 Antibodies) phosphorylation and cFos expression in AgRP (show AGRP Antibodies) neurons and promotes action potential firing of these neurons in brain slice recordings.

  3. P2Y (show P2RY1 Antibodies)(6) receptor augments pro-inflammatory responses in macrophages

  4. The results demonstrate the important role of P2Y6 as a danger signal in antiviral immune responses.

  5. these data outline a novel role for the P2Y6 receptor in the induction of CXCL8/IL-8 (show IL8 Antibodies) production and barrier dysfunction in response to C. difficile toxin exposure and may provide a new therapeutic target for the treatment of CDI.

  6. P2Y6 deficiency limits atherosclerosis and plaque inflammation in mice.

  7. P2Y (show P2RY1 Antibodies)(6) receptor signaling pathway may be a potential therapeutic target for MSU (show BCKDHA Antibodies)-associated inflammatory diseases, such as tophaceous gout.

  8. P2Y (show P2RY1 Antibodies)(6) receptor may play an important role in the regulation of bone cell function in vivo.

  9. P2Y6 receptors protect the lung against exuberant allergen-induced pulmonary inflammation by inhibiting the activation of effector T cells.

  10. our studies demonstrate that P2Y (show P2RY1 Antibodies)(6) receptor could be a novel mediator in upregulating innate immune response against the invaded pathogens through recruiting monocytes/macrophages

P2RY6 Antigen Profile

Protein Summary

The product of this gene belongs to the family of P2 receptors, which is activated by extracellular nucleotides and subdivided into P2X ligand-gated ion channels and P2Y G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor, which is a G-protein coupled receptor, is responsive to UDP, partially responsive to UTP and ADP, and not responsive to ATP. It is proposed that this receptor mediates inflammatory responses. Alternative splicing results in multiple transcript variants that encode different protein isoforms.

Gene names and symbols associated with P2RY6

  • pyrimidinergic receptor P2Y, G-protein coupled, 6 (P2RY6) antibody
  • pyrimidinergic receptor P2Y, G-protein coupled, 6 (P2ry6) antibody
  • 2010204J23Rik antibody
  • P2RY3 antibody
  • P2Y3 antibody
  • P2y6 antibody
  • P2Y6R antibody

Protein level used designations for P2RY6

G-coupled nucleotide receptor , P2 purinoceptor , P2Y purinoceptor 6 , P2Y6 receptor , P2Y ATP receptor 6 , G protein-coupled P2 receptor , P2Y purinoceptor 3 , nucleoside diphosphate receptor , P2Y6 nucleotide receptor , pyrimidinergic receptor P2Y6

GENE ID SPECIES
5031 Homo sapiens
233571 Mus musculus
117264 Rattus norvegicus
396114 Gallus gallus
485202 Canis lupus familiaris
100512849 Sus scrofa
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