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RAE1 RNA Export 1 Homolog (S. Pombe) Proteins (RAE1)

Mutations in the Schizosaccharomyces pombe Rae1 and Saccharomyces cerevisiae Gle2 genes have been shown to result in accumulation of poly(A)-containing mRNA in the nucleus, suggesting that the encoded proteins are involved in RNA export. Additionally we are shipping RAE1 Antibodies (54) and RAE1 Kits (3) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
RAE1 66679 Q8C570
RAE1 362281 Q3SWS8
RAE1 8480 P78406
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Top RAE1 Proteins at antibodies-online.com

Showing 9 out of 10 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Yeast Zebrafish His tag   1 mg Log in to see 56 to 66 Days
$3,008.50
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$3,008.50
Details
Yeast Macaca fascicularis His tag   1 mg Log in to see 56 to 66 Days
$3,008.50
Details
Yeast Xenopus tropicalis His tag   1 mg Log in to see 56 to 66 Days
$3,008.50
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,008.50
Details
Yeast Wild boar His tag   1 mg Log in to see 56 to 66 Days
$3,008.50
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

RAE1 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Rat (Rattus)

Human ,

More Proteins for RAE1 RNA Export 1 Homolog (S. Pombe) (RAE1) Interaction Partners

Mouse (Murine) RAE1 RNA Export 1 Homolog (S. Pombe) (RAE1) interaction partners

  1. Viral infection of cultured cells increased RAE-1 expression, resulting in enhanced NK cell-mediated killing through NKG2D (show KLRK1 Proteins) recognition.

  2. An increased expression of the NKG2D (show KLRK1 Proteins) ligand MICA (show MICA Proteins) in systemic lupus erthematosus (SLE) patients' kidneys and Rae-1 and Mult-1 (show ULBP1 Proteins) in various murine SLE models, is reported.

  3. Desiccating stress-induced chemokine (show CCL1 Proteins) expression in the epithelium is dependent on upregulation of NKG2D (show KLRK1 Proteins)/RAE-1 and release of IFN-gamma (show IFNG Proteins) in experimental dry eye.

  4. Highly target-specific liver NKT (show CTSL1 Proteins) cells selectively remove activated hepatic stellate cells through an NKG2D (show KLRK1 Proteins)-Rae1 interaction to ameliorate liver fibrosis after IL-30 treatment.

  5. Results suggest that genomic damage in tumor cells leads to activation of STING-dependent DNA sensor pathways, thereby activating RAE1 and enabling tumor immunosurveillance.

  6. GM-SCF (show KITLG Proteins), IL-21 (show IL21 Proteins) and Rae1 expression, alone or in combination, induces a cellular immune response against H22 tumor cells.

  7. mouse cytomegalovirus m152/gp40 interaction with RAE1gamma structural analysis reveals a paradigm for MHC/MHC interaction in immune evasion

  8. Expression of RAE-1 proteins on erythroblast surfaces increased early after Friend virus inoculation and infected erythroid cells are recognized by natural killer cells mainly through the NKG2D (show KLRK1 Proteins)-RAE-1 interactions in vivo.

  9. VSV M protein blocks mRNA export by disrupting Rae1 function, which can be reverted by induction of Rae1 expression.

  10. results suggest that Rae1 and Nup98 (show NUP98 Proteins) are temporal regulators of APC (show APC Proteins)(Cdh1 (show CDH1 Proteins)) that maintain euploidy by preventing unscheduled degradation of securin (show PTTG1 Proteins)

Human RAE1 RNA Export 1 Homolog (S. Pombe) (RAE1) interaction partners

  1. Vesiculoviral matrix (M) protein occupies nucleic acid binding site at nucleoporin (show AGFG2 Proteins) pair (Rae1 * Nup98 (show NUP98 Proteins)).

  2. vesicular stomatitis virus M protein interacted efficiently with Rae1-Nup98 (show NUP98 Proteins) complexes associated with the chromatin fraction of host nuclei, consistent with an effect on host transcription

  3. mouse cytomegalovirus m152/gp40 interaction with RAE1gamma structural analysis reveals a paradigm for MHC/MHC interaction in immune evasion

  4. This study established a novel postmitotic function for rae-1 in neuronal development.

  5. RAE1 transgene orchestrates proper chromosome segregation and NUP98 (show NUP98 Proteins)-mediated leukemogenesis.

  6. In a transgenic mouse model of chronic natural killer NKG2D (show KLRK1 Proteins) ligand expression, constant exposure to NKG2D (show KLRK1 Proteins) ligand RNA export 1 homolog (Rae-1 epsilon (show RAET1E Proteins)) does not functionally impair NK cells or CD8 (show CD8A Proteins)-positive T cells in the context of viral infection.

  7. present the crystal structure of human Rae1 in complex with the Gle2-binding sequence (GLEBS) of Nup98 (show NUP98 Proteins) at 1.65 A resolution. Rae1 forms a seven-bladed beta-propeller with several extensive surface loops.

  8. Interaction between Rae1 and cohesin subunit SMC1 (show SMC1A Proteins) is required for proper spindle formation.

  9. These data show an association of mrnp41 with MT and, moreover, demonstrate that an intact MT system is necessary for dispersion of mrnp41-containing particles to the cellular periphery

  10. VSV M protein blocks mRNA export by disrupting Rae1 function, which can be reverted by induction of Rae1 expression.

RAE1 Protein Profile

Protein Summary

Mutations in the Schizosaccharomyces pombe Rae1 and Saccharomyces cerevisiae Gle2 genes have been shown to result in accumulation of poly(A)-containing mRNA in the nucleus, suggesting that the encoded proteins are involved in RNA export. The protein encoded by this gene is a homolog of yeast Rae1. It contains four WD40 motifs, and has been shown to localize to distinct foci in the nucleoplasm, to the nuclear rim, and to meshwork-like structures throughout the cytoplasm. This gene is thought to be involved in nucleocytoplasmic transport, and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton. Alternatively spliced transcript variants encoding the same protein have been found for this gene.

Gene names and symbols associated with RAE1

  • RAE1 RNA export 1 homolog (rae1)
  • RAE1 RNA export 1 homolog (Rae1)
  • RAE1 RNA export 1 homolog (S. pombe) (RAE1)
  • RAE1 RNA export 1 homolog (S. pombe) (rae1)
  • RAE1 RNA export 1 homolog (S. pombe) (Rae1)
  • ribonucleic acid export 1 (RAE1)
  • 41 protein
  • 3230401I12Rik protein
  • D2Ertd342e protein
  • dJ481F12.3 protein
  • dJ800J21.1 protein
  • gle2 protein
  • MIG14 protein
  • MNRP protein
  • Mnrp41 protein
  • MRNP41 protein
  • zgc:56449 protein
  • zgc:77723 protein

Protein level used designations for RAE1

mRNA export factor , mRNA-associated protein mrnp 41 , rae1 protein homolog , GLEAN_09967 , RAE1 (RNA export 1, S.pombe) homolog , RAE1 RNA export 1 homolog , homolog of yeast Rae1 (Bharathi) mRNA-associated protein of 41 kDa (Kraemer) , mRNA export protein , mRNA-associated protein MRNP 41 , mRNA-binding protein, 41-kD , migration-inducing gene 14

GENE ID SPECIES
549896 Xenopus (Silurana) tropicalis
664096 Tribolium castaneum
100171527 Pongo abelii
100049109 Xenopus laevis
393973 Danio rerio
419324 Gallus gallus
485942 Canis lupus familiaris
100125839 Sus scrofa
513080 Bos taurus
66679 Mus musculus
362281 Rattus norvegicus
8480 Homo sapiens
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