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RAN Guanine Nucleotide Release Factor Proteins (RANGRF)

RANGRF encodes a protein that has been shown to function as a guanine nucleotide release factor in mouse and to regulate the expression and function of the Nav1.5 cardiac sodium channel in human. Additionally we are shipping RAN Guanine Nucleotide Release Factor Antibodies (9) and RAN Guanine Nucleotide Release Factor Kits (3) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat RANGRF RANGRF 287419  
RANGRF 29098 Q9HD47
RANGRF 57785 Q9JIB0
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Top RAN Guanine Nucleotide Release Factor Proteins at antibodies-online.com

Showing 7 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 7 to 8 Days
$319.00
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,442.00
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 3 to 4 Days
$382.86
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

RANGRF Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

Top referenced RAN Guanine Nucleotide Release Factor Proteins

  1. Human RANGRF Protein expressed in Escherichia coli (E. coli) - ABIN1098330 : Kattygnarath, Maugenre, Neyroud, Balse, Ichai, Denjoy, Dilanian, Martins, Fressart, Berthet, Schott, Leenhardt, Probst, Le Marec, Hainque, Coulombe, Hatem, Guicheney: MOG1: a new susceptibility gene for Brugada syndrome. in Circulation. Cardiovascular genetics 2011 (PubMed)
    Show all 2 references for ABIN1098330

More Proteins for RAN Guanine Nucleotide Release Factor (RANGRF) Interaction Partners

Human RAN Guanine Nucleotide Release Factor (RANGRF) interaction partners

  1. Compound mutation of CACNA2D1 (show CACNA2D1 Proteins) and RANGRF genes were found. To the best of our knowledge, this is the first comprehensive description of the concurrence of these two mutations and histiocytoid cardiomyopathy.

  2. Results suggest that dominant-negative mutations in MOG1 can impair the trafficking of Na(v)1.5 to the membrane, leading to I(Na) reduction and clinical manifestation of Brugada syndrome.

  3. Our screening of Nav1.5 (show SCN5A Proteins) cofactor MOG1 uncovered a novel nonsense variant that appeared to be present at a higher frequency among these patients with atrial fibrillation and Brugada syndrome than control subjects.

  4. in cardiomyocytes, MOG1 is mostly localized in the cell membrane and co-localized with Nav1.5 (show SCN5A Proteins), indicating that MOG1 is a critical regulator of sodium channel function in the heart

Mouse (Murine) RAN Guanine Nucleotide Release Factor (RANGRF) interaction partners

  1. in cardiomyocytes, MOG1 is mostly localized in the cell membrane and co-localized with Nav1.5 (show SCN5A Proteins), indicating that MOG1 is a critical regulator of sodium channel function in the heart

RAN Guanine Nucleotide Release Factor (RANGRF) Protein Profile

Protein Summary

This gene encodes a protein that has been shown to function as a guanine nucleotide release factor in mouse and to regulate the expression and function of the Nav1.5 cardiac sodium channel in human. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with RANGRF

  • RAN guanine nucleotide release factor (Rangrf)
  • RAN guanine nucleotide release factor (rangrf)
  • RAN guanine nucleotide release factor (RANGRF)
  • si:ch211-268m12.6 (si:ch211-268m12.6)
  • Mog1 family protein (DDB_G0285871)
  • ran guanine nucleotide release factor (mog1)
  • 2400006H24Rik protein
  • DDBDRAFT_0186722 protein
  • DDBDRAFT_0237751 protein
  • DDB_0186722 protein
  • DDB_0237751 protein
  • HSPC236 protein
  • Mog1 protein
  • Rangnrf protein
  • RANGRF protein
  • RGD1563195 protein
  • zmynd19 protein

Protein level used designations for RANGRF

ran guanine nucleotide release factor , RAN guanine nucleotide release factor , zinc finger, MYND domain containing 19 , Ran GTPase binding protein , MOG1 homolog , ran-binding protein MOG1

GENE ID SPECIES
287419 Rattus norvegicus
398168 Xenopus laevis
479494 Canis lupus familiaris
496602 Xenopus (Silurana) tropicalis
559102 Danio rerio
8625326 Dictyostelium discoideum AX4
100529008 Ictalurus punctatus
29098 Homo sapiens
57785 Mus musculus
512506 Bos taurus
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