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RAP1B, Member of RAS Oncogene Family Proteins (RAP1B)

RAP1B encodes a member of the RAS-like small GTP-binding protein superfamily. Additionally we are shipping RAP1B, Member of RAS Oncogene Family Antibodies (35) and RAP1B, Member of RAS Oncogene Family Kits (4) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
RAP1B 5908 P61224
RAP1B 171337 Q62636
RAP1B 215449 Q99JI6
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Top RAP1B, Member of RAS Oncogene Family Proteins at antibodies-online.com

Showing 10 out of 15 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 50 μg Log in to see 7 to 8 Days
$407.00
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Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,427.33
Details
Yeast Xenopus laevis His tag   1 mg Log in to see 56 to 66 Days
$2,427.33
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Yeast Pan troglodytes His tag   1 mg Log in to see 56 to 66 Days
$2,427.33
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Yeast Cyprinus carpio His tag   1 mg Log in to see 56 to 66 Days
$2,427.33
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Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,427.33
Details
Yeast Macaca fascicularis His tag   1 mg Log in to see 56 to 66 Days
$2,427.33
Details

RAP1B Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Rat (Rattus)

Mouse (Murine)

Top referenced RAP1B, Member of RAS Oncogene Family Proteins

  1. Human RAP1B Protein expressed in Escherichia coli (E. coli) - ABIN667867 : Awasthi, Samarakoon, Chu, Kamalakannan, Quilliam, Chrzanowska-Wodnicka, White, Malarkannan: Rap1b facilitates NK cell functions via IQGAP1-mediated signalosomes. in The Journal of experimental medicine 2010 (PubMed)
    Show all 2 references for ABIN667867

  2. Human RAP1B Protein expressed in Wheat germ - ABIN1317394 : Chu, Awasthi, White, Chrzanowska-Wodnicka, Malarkannan: Rap1b regulates B cell development, homing, and T cell-dependent humoral immunity. in Journal of immunology (Baltimore, Md. : 1950) 2008 (PubMed)

More Proteins for RAP1B, Member of RAS Oncogene Family (RAP1B) Interaction Partners

Human RAP1B, Member of RAS Oncogene Family (RAP1B) interaction partners

  1. The protein expression of RAP1B and HIF-1 alpha (show HIF1A Proteins) contributed to gastric cancer malignant behavior and poor prognosis.

  2. Cholera toxin and beta-adrenergic receptor activation phosphorylate Rap1B and inhibit its prenylation and membrane localization.

  3. Glucocorticoids mediate induction of microRNA-708 to suppress ovarian cancer metastasis through targeting Rap1B.

  4. Adenosine signaling reduces prenylation and plasma membrane localization of Rap1B, resulting in enhanced tumor cell scattering and invasiveness.

  5. High concentrations of extracellular adenosine in the tumor microenvironment can chronically activate A2B (show ADORA2B Proteins) receptors to suppress Rap1B prenylation and signaling at the cell membrane, resulting in reduced cell-cell contact and promoting cell scattering.

  6. TMZ as a standard chemotherapeutic agent for GBM inhibits the Rap1B expression and actin cytoskeleton remodeling to exert its cell killing by upregulating miR (show MLXIP Proteins)-181a/b/c/d subunits

  7. Rap1b in both smooth muscle and endothelium plays a key role in maintaining blood pressure by controlling normal vascular tone.

  8. findings show Rap1b expression decreased significantly in tubules of renal biopsies from patients with diabetic nephropathy (DN); findings indicate Rap1b ameliorates tubular injury and slows progression of DN by modulation of mitochondrial dysfunction via C/EBP-beta-PGC-1alpha signaling

  9. Hepatitis B virus down-regulated miR (show MLXIP Proteins)-101-3p expression, which resulted in up-regulation of Rap1b, and down-regulation of miR (show MLXIP Proteins)-101-3p or up-regulation of Rap1b promoted proliferation and migration of hepatocellular carcinoma cells

  10. phosphorylation of CalDAG-GEFI (show RASGRP1 Proteins) is a critical mechanism by which PKA controls Rap1b-dependent platelet aggregation

Mouse (Murine) RAP1B, Member of RAS Oncogene Family (RAP1B) interaction partners

  1. These findings ascribe a new function to SLAT, and identify Rap1 as a target of SLAT function in TCR-mediated inside-out signaling.

  2. Rap1 Is Essential for Mouse Development and Formation of Functional Vasculature

  3. findings reveal key roles for the bidirectional synaptic expression of the Rap1b small GTPase (show RACGAP1 Proteins) and an associated local synaptic protein translation network in this process.

  4. Rap1 deficiency impaired T-cell homeostasis.

  5. Rap1b deficiency promoted the transcellular route of diapedesis through endothelial cell. Increased transcellular migration of Rap1b-deficient neutrophils in vitro was selectively mediated by enhanced PI3K-Akt (show AKT1 Proteins) activation and invadopodia-like protrusions.

  6. Rap1b in both smooth muscle and endothelium plays a key role in maintaining blood pressure by controlling normal vascular tone.

  7. Talin1 and Rap1 are critical for resorptive function, and their selective inhibition in mature osteoclasts retards pathological bone loss.

  8. two different activation mechanisms of Rap1b as well as novel functions of Rap1b in platelet secretion and in integrin alpha(IIb)beta(3) outside-in signaling.

  9. Rap1b-dependent VEGF (show VEGFA Proteins)-VEGFR2 (show KDR Proteins) activation is in part mediated via integrin alpha(v (show ITGAV Proteins))beta(3).

  10. Upon activation, Rap1b colocalized with the scaffolding protein IQGAP1.

RAP1B, Member of RAS Oncogene Family (RAP1B) Protein Profile

Protein Summary

This gene encodes a member of the RAS-like small GTP-binding protein superfamily. Members of this family regulate multiple cellular processes including cell adhesion and growth and differentiation. This protein localizes to cellular membranes and has been shown to regulate integrin-mediated cell signaling. This protein also plays a role in regulating outside-in signaling in platelets. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 3, 5, 6 and 9.

Gene names and symbols associated with RAP1B

  • RAP1B, member of RAS oncogene family (RAP1B)
  • RAP1B, member of RAS oncogene family (LOC693750)
  • RAP1B, member of RAS oncogene family (Bm1_39445)
  • RAP1B, member of RAS oncogene family (LOC100223739)
  • RAP1B, member of RAS oncogene family (LOC100339891)
  • RAP1B, member of RAS oncogene family (Rap1b)
  • RAP1B, member of RAS oncogene family (rap1b)
  • RAS related protein 1b (Rap1b)
  • 2810443E11Rik protein
  • k-rev protein
  • ral1b protein

Protein level used designations for RAP1B

RAP1B, member of RAS oncogene family , ras-related protein Rap-1b , GTP-binding protein smg p21B , RAS-related protein RAP1B , Ras family small GTP binding protein RAP1B , small GTP binding protein , RAS related protein 1b

GENE ID SPECIES
608981 Canis lupus familiaris
693750 Macaca mulatta
718171 Macaca mulatta
6102773 Brugia malayi
100171907 Pongo abelii
100223739 Taeniopygia guttata
100339891 Oryctolagus cuniculus
5908 Homo sapiens
171337 Rattus norvegicus
327708 Bos taurus
417840 Gallus gallus
452065 Pan troglodytes
379883 Xenopus laevis
215449 Mus musculus
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