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RASD Family, Member 2 Proteins (RASD2)

RASD2 encodes a Ras-related protein that enriched in striatum. Additionally we are shipping RASD Family, Member 2 Antibodies (83) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
RASD2 23551 Q96D21
RASD2 171099 P63033
RASD2 75141 P63032
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Top RASD Family, Member 2 Proteins at antibodies-online.com

Showing 6 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,682.17
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   5 applications Log in to see 1 to 2 Days
$312.71
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

RASD2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Rat (Rattus) ,

Mouse (Murine)

Top referenced RASD Family, Member 2 Proteins

  1. Human RASD2 Protein expressed in Wheat germ - ABIN1317482 : Harrison, Lahoste, Ruskin: Ontogeny and dopaminergic regulation in brain of Ras homolog enriched in striatum (Rhes). in Brain research 2008 (PubMed)

More Proteins for RASD Family, Member 2 (RASD2) Interaction Partners

Human RASD Family, Member 2 (RASD2) interaction partners

  1. Study demonstrated that variation in the gene coding for RASD2 (rs6518956) affects in vivo prefrontal and striatal phenotypes in healthy human subjects that are relevant to schizophrenia

  2. Rhes influences striatal cAMP/PKA-dependent signaling and synaptic plasticity in a gender-sensitive fashion

  3. Findings reveal that ras homolog enriched in striatum is localized also in striatal cholinergic interneurons and, most importantly, lack of this G-protein, significantly alters dopamine D2 receptor (show DRD2 Proteins) modulation of striatal cholinergic excitability.

  4. Rhes is reduced in the brains of Huntington's disease patients.

  5. The findings of this study suggested that Rhes may play a crucial role in striatal iron homeostasis.

  6. Rhes robustly binds the autophagy regulator Beclin-1 (show BECN1 Proteins), decreasing its inhibitory interaction with Bcl-2 (show BCL2 Proteins) independent of JNK-1 (show MAPK8 Proteins) signaling.

  7. The sequestering of Rhes through its binding to mutant huntingtin (show HTT Proteins) may decrease the ability of Rhes to perform vital physiological functions in the striatum neurons of Huntington disease (show HTT Proteins) patients. (Review)

  8. Rhes is an imidazoline-regulated transcript in pancreatic beta-cells

  9. Rhes can interfere with the functional activity of wt and mutated TSHr (show TSHR Proteins) and with the respective hormone-stimulated cAMP production of FSHr (show FSHR Proteins) and LHr (show LHCGR Proteins).

  10. The genes RASD2 might be vulnerability genes for neuropsychologically defined subgroups of schizophrenic patients.

Mouse (Murine) RASD Family, Member 2 (RASD2) interaction partners

  1. that Rasd2 mutants display deficits in basal prepulse inhibition that, in turn, exacerbate gating disruption under psychotomimetic drug challenge

  2. Study showed that both genetic deletion of Rhes and pharmacological blockade of mTORC1 significantly attenuate dyskinesia development by reducing the sensitization of striato-nigral medium-sized spiny neurons to levodopa

  3. ectopic expression of Rhes in the cerebellum of N171-82Q mice, during the asymptomatic period led to an exacerbation of motor deficits, including loss of balance and motor incoordination with ataxia (show USP14 Proteins)-like features

  4. Rhes influences striatal cAMP/PKA-dependent signaling and synaptic plasticity in a gender-sensitive fashion

  5. Brain Rhes expression is decreased in a mouse model of Huntington's disease.

  6. Rhes robustly binds the autophagy regulator Beclin-1 (show BECN1 Proteins), decreasing its inhibitory interaction with Bcl-2 (show BCL2 Proteins) independent of JNK-1 (show MAPK8 Proteins) signaling.

  7. Rhes is necessary for Akt (show AKT1 Proteins) dephosphorylation by the striatal multi-protein complex

  8. behavioral symptoms of HD are regulated by Rhes

  9. This study demonstrated that Rhes-deleted mice are dramatically protected from neurotoxicity and motor dysfunction in a striatal-specific model of Huntington's disease elicited by 3-nitropropionic acid.

  10. Ths results of this study indicted that Rhes physiologically binds to and activates mTOR (show FRAP1 Proteins) in the striatum and L-DOPA-induced dyskinesia.

RASD Family, Member 2 (RASD2) Protein Profile

Protein Summary

This gene encodes a Ras-related protein that enriched in striatum. The product of this gene binds to GTP and possesses intrinsic GTPase activity. The gene belongs to the Ras superfamily of small GTPases. The exact function of this gene is unknown, but most striatum-specific mRNAs characterized to date encode components of signal transduction cascades.

Gene names and symbols associated with RASD Family, Member 2 Proteins (RASD2)

  • RASD family, member 2 (RASD2)
  • RASD family, member 2 (Rasd2)
  • 4930526B11Rik protein
  • AU045414 protein
  • MGC:4834 protein
  • RASD2 protein
  • Rhes protein
  • TEM-2 protein
  • TEM2 protein

Protein level used designations for RASD Family, Member 2 Proteins (RASD2)

RASD family, member 2 , GTP-binding protein Rhes , Ras homolog enriched in striatum , tumor endothelial marker 2 , SE6C , ras homolog enriched in striatum

GENE ID SPECIES
418057 Gallus gallus
470196 Pan troglodytes
527921 Bos taurus
23551 Homo sapiens
171099 Rattus norvegicus
481284 Canis lupus familiaris
75141 Mus musculus
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