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Ras Interacting Protein 1 Proteins (RASIP1)

Required for the proper formation of vascular structures that develop via both vasculogenesis and angiogenesis. Additionally we are shipping RASIP1 Antibodies (30) and and many more products for this protein.

list all proteins Gene Name GeneID UniProt
RASIP1 54922 Q5U651
RASIP1 69903 Q3U0S6
Rat RASIP1 RASIP1 292912  
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Top RASIP1 Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

RASIP1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for Ras Interacting Protein 1 (RASIP1) Interaction Partners

Human Ras Interacting Protein 1 (RASIP1) interaction partners

  1. results reveal an effector pathway for Rap1 in the modulation of Rho signaling and actin dynamics, through which Rap1 modulates endothelial barrier function

  2. Rain is a novel protein that can serve as an effector of endomembrane-localized Ras

Mouse (Murine) Ras Interacting Protein 1 (RASIP1) interaction partners

  1. we summarize recent developments in understanding the small G protein (show RAC2 Proteins) RAP1 (show TERF2IP Proteins) and its effector RASIP1 as critical mediators of endothelial junction stabilization.

  2. RASIP1 regulates the integrity of newly formed blood vessels as an effector of EPAC1-RAP1 signaling.

  3. Mice lacking Rasip1 fail to form patent lumens in all blood vessels, including the early endocardial tube. Rasipl null angioblasts fail to properly localize the polarity determinant Par3 (show F2RL2 Proteins) and display defective cell polarity.

  4. Rain is a novel protein that can serve as an effector of endomembrane-localized Ras

  5. Rasip1 expression is undetectable in VEGFR2 (show KDR Proteins) null embryos, which lack endothelial cells, suggesting that Rasip1 is endothelial specific. siRNA-mediated reduction of Rasip1 severely impairs angiogenesis and motility in endothelial cell cultures

RASIP1 Protein Profile

Protein Summary

Required for the proper formation of vascular structures that develop via both vasculogenesis and angiogenesis. Acts as a critical and vascular-specific regulator of GTPase signaling, cell architecture, and adhesion, which is essential for endothelial cell morphogenesis and blood vessel tubulogenesis. Regulates the activity of Rho GTPases in part by recruiting ARHGAP29 and suppressing RhoA signaling and dampening ROCK and MYH9 activities in endothelial cells. May act as effector for Golgi-bound HRAS and other Ras-like proteins. May promote HRAS-mediated transformation.

Gene names and symbols associated with RASIP1

  • Ras interacting protein 1 (RASIP1)
  • Ras interacting protein 1 (Rasip1)
  • 1110025D03Rik protein
  • 2610025P08Rik protein
  • AI853551 protein
  • Rain protein

Protein level used designations for RASIP1

Ras interacting protein 1 , ras-interacting protein 1

GENE ID SPECIES
484397 Canis lupus familiaris
54922 Homo sapiens
69903 Mus musculus
292912 Rattus norvegicus
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