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binds GTP; member of the subfamily of Ras-homologous GTP binding proteins. Additionally we are shipping Ras-Related GTP Binding A Proteins (11) and many more products for this protein.
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Human Polyclonal RRAGA Primary Antibody for WB - ABIN2452102
Sekiguchi, Todaka, Wang, Hirose, Nakashima, Nishimoto: A novel human nucleolar protein, Nop132, binds to the G proteins, RRAG A/C/D. in The Journal of biological chemistry 2004
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The data indicate that the RRAGA mutations, associated with autosomal dominant cataracts, play a role in the disease by acting through disruption of mTORC1 signaling.
Data suggest that both microtubule-associated DYNLT (dynein light chain Tctex-type 1 (show DYNLT1 Antibodies)) and cytoplasmic DYNLT (dynein 1 intermediate chain 2 DYNC1LI2 (show DYNC1LI2 Antibodies)) are equally able to bind to small GTPases Rab3D (Rab3d (show RAB3D Antibodies) GTPase (show RACGAP1 Antibodies)) and RagA (Ras-related GTP binding A).
Data suugest that S-phase kinase-associated protein 2 (Skp2)-mediated Ras-related GTP-binding protein RagA ubiquitination recruits GATOR1 to restrict mTORC1 signaling upon sustained amino acid stimulation.
A mechanism for regulation of mTORC1 signaling by RNF152-mediated K63-linked polyubiquitination of RagA.
RagA and RagB (show RRAGB Antibodies) are key regulators of lysosomal function and cardiac protection.
RagA deficiency leads to E10.5 embryonic death, loss of mTORC1 activity, and severe growth defects.
Fip1 expression and the Fip1-dependent mRNA alternative polyadenylation program change during embryonic stem cell differentiation and are restored to an embryonic stem cell-like state during somatic reprogramming.
Overexpression of constitutively active (ca)RagA and caRagC increased mTORC1 activity, as determined by increased S6K1 (show RPS6KB1 Antibodies) phosphorylation.
binds GTP\; member of the subfamily of Ras-homologous GTP binding proteins
, ras-related GTP-binding protein A
, adenovirus E3 14.7 kDa-interacting protein 1
, adenovirus E3-14.7K interacting protein 1
, Ras-related GTP-binding protein ragA