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The protein encoded by RECK is a cysteine-rich, extracellular protein with protease inhibitor-like domains whose expression is suppressed strongly in many tumors and cells transformed by various kinds of oncogenes. Additionally we are shipping RECK Kits (5) and RECK Proteins (4) and many more products for this protein.
Showing 10 out of 66 products:
Human Monoclonal RECK Primary Antibody for IF, WB - ABIN968568
Sasahara, Takahashi, Noda: Involvement of the Sp1 site in ras-mediated downregulation of the RECK metastasis suppressor gene. in Biochemical and biophysical research communications 1999
Show all 3 references for ABIN968568
Human Polyclonal RECK Primary Antibody for EIA, FACS - ABIN954495
Du, Dai, Yang: Role of RECK methylation in gastric cancer and its clinical significance. in World journal of gastroenterology : WJG 2010
Show all 2 references for ABIN954495
Human Monoclonal RECK Primary Antibody for WB - ABIN1108847
Johnson, Kozma, Colombari: Carbon monoxide: from toxin to endogenous modulator of cardiovascular functions. in Brazilian journal of medical and biological research = Revista brasileira de pesquisas médicas e biológicas / Sociedade Brasileira de Biofísica ... [et al.] 1999
Show all 2 references for ABIN1108847
Human Polyclonal RECK Primary Antibody for IF (cc), IF (p) - ABIN681418
Siddesha, Valente, Sakamuri, Gardner, Delafontaine, Noda, Chandrasekar: Acetylsalicylic acid inhibits IL-18-induced cardiac fibroblast migration through the induction of RECK. in Journal of cellular physiology 2014
Show all 2 references for ABIN681418
Human Polyclonal RECK Primary Antibody for IF, IHC - ABIN1533572
Humphray, Oliver, Hunt, Plumb, Loveland, Howe, Andrews, Searle, Hunt, Scott, Jones, Ainscough, Almeida, Ambrose, Ashwell, Babbage, Babbage, Bagguley, Bailey, Banerjee, Barker, Barlow, Bates, Beasley et al.: DNA sequence and analysis of human chromosome 9. ... in Nature 2004
RECK Gene Promoter rs10814325 Polymorphism is associated with metastasis in Hepatocellular Carcinoma
the aim of this study was to analyze the effect of RECK gene rs 11788747 single nucleotide polymorphism (SNP) on hepatocellular carcinoma (HCC (show FAM126A Antibodies)) susceptibility.
Findings suggest that RECK transcript variants might have opposite roles in GBM biology and the ratio of their expression levels may be informative for the prognostic outcome of GBM patients.
miR (show MLXIP Antibodies)-21 has a role in upregulating PTEN (show PTEN Antibodies), RECK and PDCD4 (show PDCD4 Antibodies) in glioma
RECK is a regulator of hMSC functions suggesting that modulation of RECK may improve the development of hMSC-based therapeutical approaches in regenerative medicine.
MMP-9 (show MMP9 Antibodies)/RECK imbalance in cervical smears is significantly associated with high-grade cervical diseases and infection by alpha-9 HPV and C. trachomatis.
RECK is not an independent prognostic marker for breast cancer
miR (show MLXIP Antibodies)-221/miR (show MLXIP Antibodies)-222-RECK axis might be an important path modulating H. pylori infection-related gastric cancer development
Expression of RECK is associated with the incidence of restenosis after vascular angioplasty. RECK may be induced as a part of the intrinsic defense mechanism against restenosis.
This downregulation of RECK in advanced grades of osteosarcoma and metastatic grades was also associated with the increased expression of invadosome-specific markers like MMP9 (show MMP9 Antibodies)
These findings demonstrate the importance of appropriate cell-cell interactions and ECM (show MMRN1 Antibodies) maintenance for angiogenesis and the involvement of Reck as a critical regulator of these events.
RECK-mediated beta1-Integrin regulation by TGF-beta1 (show TGFB1 Antibodies) is critical for wound contraction in mice.
MiR (show MLXIP Antibodies)-21 modulated the osteoporosis by targeting RECK.
microRNA-200b and microRNA-200c promote colorectal cancer cell proliferation via targeting RECK.
The RECK silencing-EGFR (show EGFR Antibodies)-HIF-2alpha (show EPAS1 Antibodies) axis might be a key molecular mechanism to induce hyperplastic phenotype of epithelial cells.
Angiotensin II suppresses RECK, but induces matrix metalloproteinases both in vivo and in vitro.
therapeutic concentrations of ASA (show ARSA Antibodies) inhibited IL-18 (show IL18 Antibodies)-induced H(2)O(2) generation, MMP9 (show MMP9 Antibodies) activation, RECK suppression, and CF migration.
these data suggest that RECK is a novel transcriptional target of FXR (show NR1H4 Antibodies) in mouse liver, and provide clues to better understanding the function of FXR (show NR1H4 Antibodies) in liver.
RECK expression in the mouse uterus is steroidally regulated and within endometrial epithelial and stromal cells, RECK regulates MMP9 (show MMP9 Antibodies), but not MMP2 (show MMP2 Antibodies) activity.
After treatment with NS398, RECK expression increased and MMP9 (show MMP9 Antibodies) expression decreased in mice with prostate cancer.
The protein encoded by this gene is a cysteine-rich, extracellular protein with protease inhibitor-like domains whose expression is suppressed strongly in many tumors and cells transformed by various kinds of oncogenes. In normal cells, this membrane-anchored glycoprotein may serve as a negative regulator for matrix metalloproteinase-9, a key enzyme involved in tumor invasion and metastasis.
membrane-anchored glycoprotein (metastasis and invasion)
, reversion-inducing cysteine-rich protein with Kazal motifs
, suppression of tumorigenicity 15 (reversion-inducing-cysteine-rich protein with kazal motifs)
, suppression of tumorigenicity 5 (reversion-inducing-cysteine-rich protein with kazal motifs)
, suppressor of tumorigenicity 15 protein
, Reversion-inducing cysteine-rich protein with Kazal motifs precursor (mRECK)
, membrane-anchored glycoprotein RECK
, suppression of tumorigenicity 15
, reversion-inducing-cysteine-rich protein with Kasal motifs