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anti-Ribonuclease H2, Subunit A (RNASEH2A) Antibodies

The protein encoded by RNASEH2A is a component of the heterotrimeric type II ribonuclease H enzyme (RNAseH2). Additionally we are shipping RNASEH2A Proteins (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
RNASEH2A 69724 Q9CWY8
RNASEH2A 10535 O75792
RNASEH2A 364974 Q5U209
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Top anti-RNASEH2A Antibodies at antibodies-online.com

Showing 10 out of 39 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC, WB WB Suggested Anti-RNASEH2A Antibody Titration: 0.2-1 ug/mlPositive Control: Jurkat cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated IHC, WB WB Suggested Anti-RNASEH2A Antibody Titration: 1.25ug/mlPositive Control: Jurkat cell lysate 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Rabbit Un-conjugated IF, WB Immunocytochemistry of RNAse H2A in HeLa cells with this product at 2 μg/ml. Western blot analysis of RNAse H2A in HeLa cell lysate with this product at 1 μg/ml. 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated IHC, WB 100 μg Log in to see 8 to 10 Days
$493.17
Details
Human Rabbit Un-conjugated IHC, WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated IHC, ELISA, WB 100 μg Log in to see 2 to 3 Days
$343.75
Details
Human Rabbit Un-conjugated IHC, ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Mouse Un-conjugated WB Western Blot analysis of RNASEH2A expression in transfected 293T cell line by RNASEH2A monoclonal antibody (M01), clone 3G5-F5. Lane 1: RNASEH2A transfected lysate(33.4 KDa). Lane 2: Non-transfected lysate. Western blot analysis of RNASEH2A over-expressed 293 cell line, cotransfected with RNASEH2A Validated Chimera RNAi used as specificity and loading control. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated IHC, WB RNASEH2A antibody was used for immunohistochemistry at a concentration of 4-8 ug/ml to stain Epithelial cells of renal tubule (arrows) in Human Kidney. Magnification is at 400X RNASEH2A antibody used at 1.25 ug/ml to detect target protein. 100 μg Log in to see 3 to 4 Days
$388.93
Details
Human Rabbit Un-conjugated ICC, ELISA, WB 100 μg Log in to see 8 to 10 Days
$522.50
Details

RNASEH2A Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine)


Human ,
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Rat (Rattus)


Top referenced anti-RNASEH2A Antibodies

  1. Human Polyclonal RNASEH2A Primary Antibody for IF, WB - ABIN500622 : Stein, Hausen: Enzyme from calf thymus degrading the RNA moiety of DNA-RNA Hybrids: effect on DNA-dependent RNA polymerase. in Science (New York, N.Y.) 1970 (PubMed)
    Show all 4 references for ABIN500622

  2. Human Polyclonal RNASEH2A Primary Antibody for IHC, WB - ABIN2778984 : Frank, Braunshofer-Reiter, Wintersberger, Grimm, Büsen: Cloning of the cDNA encoding the large subunit of human RNase HI, a homologue of the prokaryotic RNase HII. in Proceedings of the National Academy of Sciences of the United States of America 1998 (PubMed)

More Antibodies against RNASEH2A Interaction Partners

Mouse (Murine) Ribonuclease H2, Subunit A (RNASEH2A) interaction partners

  1. the G37S mutation of RNaseH2 led to increased expression of interferon (show IFNA Antibodies)-stimulated genes dependent on the cGAS-STING signaling pathway.

  2. Recent evidence gathered from ribonuclease H2 knock-out mice provides insight into the molecular mechanisms underlying Aicardi-Goutieres syndrome development and a potential role of DNA damage as a trigger of autoimmunity is discussed. [review]

  3. analysis of the RNase H2A subunit mutations that cause Aicardi-Goutieres syndrome

  4. Data show that the interwoven architecture of RNase H2B (show RNASEH2B Antibodies) and RNase H2C (show RNASEH2C Antibodies) that interface with RNase H2A in a complex ideally suited for nucleic acid binding and hydrolysis coupled to protein-protein interaction motifs.

Human Ribonuclease H2, Subunit A (RNASEH2A) interaction partners

  1. RNase H2 complex is assembled in the cytosol and imported into the nucleus in an RNase H2B (show RNASEH2B Antibodies)-dependent manner.

  2. Studies indicate that most antiviral-defense systems involve RNase H-like enzymes destroying invading nucleic acids, RNA, or DNA.

  3. study identified two synonymous variants in RNASEH2A that result in loss of RNase H2 enzyme function and the consequent Aicardi-Goutieres syndrome phenotype

  4. analysis of the RNase H2A subunit mutations that cause Aicardi-Goutieres syndrome

RNASEH2A Antigen Profile

Protein Summary

The protein encoded by this gene is a component of the heterotrimeric type II ribonuclease H enzyme (RNAseH2). RNAseH2 is the major source of ribonuclease H activity in mammalian cells and endonucleolytically cleaves ribonucleotides. It is predicted to remove Okazaki fragment RNA primers during lagging strand DNA synthesis and to excise single ribonucleotides from DNA-DNA duplexes. Mutations in this gene cause Aicardi-Goutieres Syndrome (AGS), a an autosomal recessive neurological disorder characterized by progressive microcephaly and psychomotor retardation, intracranial calcifications, elevated levels of interferon-alpha and white blood cells in the cerebrospinal fluid.

Gene names and symbols associated with RNASEH2A

  • ribonuclease H2, subunit A (rnaseh2a) antibody
  • ribonuclease H2, subunit A (RNASEH2A) antibody
  • ribonuclease H2, large subunit (Rnaseh2a) antibody
  • ribonuclease H2, subunit A (Rnaseh2a) antibody
  • 2400006P09Rik antibody
  • AGS4 antibody
  • JUNB antibody
  • RNASEHI antibody
  • RNHIA antibody
  • RNHL antibody
  • zgc:56307 antibody

Protein level used designations for RNASEH2A

ribonuclease H2, large subunit , ribonuclease HI, large subunit , RNase H2 subunit A , RNase HI large subunit , ribonuclease H2 subunit A , ribonuclease HI large subunit , ribonuclease HI subunit A , RNase H(35) , aicardi-Goutieres syndrome 4 protein

GENE ID SPECIES
394751 Xenopus (Silurana) tropicalis
455752 Pan troglodytes
69724 Mus musculus
393195 Danio rerio
443655 Xenopus laevis
10535 Homo sapiens
484925 Canis lupus familiaris
512830 Bos taurus
364974 Rattus norvegicus
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