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The protein encoded by RNF135 contains a RING finger domain, a motif present in a variety of functionally distinct proteins and known to be involved in protein-protein and protein-DNA interactions. Additionally we are shipping Ring Finger Protein 135 Proteins (6) and many more products for this protein.
Showing 10 out of 45 products:
Human Polyclonal RNF135 Primary Antibody for WB - ABIN1881754
You, Sun, Zhou, Sun, Liang, Zhai, Jiang: PCBP2 mediates degradation of the adaptor MAVS via the HECT ubiquitin ligase AIP4. in Nature immunology 2009
Show all 3 references for ABIN1881754
Cow (Bovine) Polyclonal RNF135 Primary Antibody for WB - ABIN2775925
Petroziello, Yamane, Westendorf, Thompson, McDonagh, Cerveny, Law, Wahl, Carter: Suppression subtractive hybridization and expression profiling identifies a unique set of genes overexpressed in non-small-cell lung cancer. in Oncogene 2004
Human Polyclonal RNF135 Primary Antibody for WB - ABIN2776070
Douglas, Cilliers, Coleman, Tatton-Brown, Barker, Bernhard, Burn, Huson, Josifova, Lacombe, Malik, Mansour, Reid, Cormier-Daire, Cole, , Rahman: Mutations in RNF135, a gene within the NF1 microdeletion region, cause phenotypic abnormalities including overgrowth. in Nature genetics 2007
findings demonstrate the biological effects of RNF135 in glioblastoma cell proliferation, migration and cell cycle, and its role in the progression of glioblastoma may be associated with the ERK (show EPHB2 Antibodies) signal transduction pathway.
Data showed that the presence of the RNF135 K115 variant in the genotype of patients with autism was statistically significant.
Riplet-mediated K63-linked polyubiquitination released RIG-I (show DDX58 Antibodies) RD autorepression, which allowed the access of positive factors to the RIG-I (show DDX58 Antibodies) protein.
REUL is an E3 ubiquitin ligase (show MUL1 Antibodies) of RIG-I (show DDX58 Antibodies) and specifically stimulates RIG-I (show DDX58 Antibodies)-mediated innate antiviral activity
These data identify RNF135 as causative of a new overgrowth syndrome and demonstrate that RNF135 haploinsufficiency contributes to the phenotype of NF1 (show NF1 Antibodies) microdeletion cases.
identify an alternative factor, Riplet/RNF135, that promotes RIG-I (show DDX58 Antibodies) activation independent of TRIM25 (show TRIM25 Antibodies)
RNF135 mutations are not present in patients with Sotos (show NSD1 Antibodies) syndrome-like features.
Riplet is essential for regulating RIG-I (show DDX58 Antibodies)-mediated innate immune response against RNA virus infection in vivo.
The protein encoded by this gene contains a RING finger domain, a motif present in a variety of functionally distinct proteins and known to be involved in protein-protein and protein-DNA interactions. This gene is located in a chromosomal region known to be frequently deleted in patients with neurofibromatosis. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
E3 ubiquitin-protein ligase RNF135
, RIG-I E3 ubiquitin ligase
, U 2-3-0