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The protein encoded by RNF135 contains a RING finger domain, a motif present in a variety of functionally distinct proteins and known to be involved in protein-protein and protein-DNA interactions. Additionally we are shipping Ring Finger Protein 135 Proteins (6) and many more products for this protein.
Showing 10 out of 43 products:
Human Polyclonal RNF135 Primary Antibody for WB - ABIN1881754
You, Sun, Zhou, Sun, Liang, Zhai, Jiang: PCBP2 mediates degradation of the adaptor MAVS via the HECT ubiquitin ligase AIP4. in Nature immunology 2009
Show all 3 references for ABIN1881754
Human Polyclonal RNF135 Primary Antibody for WB - ABIN2776070
Douglas, Cilliers, Coleman, Tatton-Brown, Barker, Bernhard, Burn, Huson, Josifova, Lacombe, Malik, Mansour, Reid, Cormier-Daire, Cole, , Rahman: Mutations in RNF135, a gene within the NF1 microdeletion region, cause phenotypic abnormalities including overgrowth. in Nature genetics 2007
Cow (Bovine) Polyclonal RNF135 Primary Antibody for WB - ABIN2775925
Petroziello, Yamane, Westendorf, Thompson, McDonagh, Cerveny, Law, Wahl, Carter: Suppression subtractive hybridization and expression profiling identifies a unique set of genes overexpressed in non-small-cell lung cancer. in Oncogene 2004
Data showed that the presence of the RNF135 K115 variant in the genotype of patients with autism was statistically significant.
Riplet-mediated K63-linked polyubiquitination released RIG-I (show DDX58 Antibodies) RD autorepression, which allowed the access of positive factors to the RIG-I (show DDX58 Antibodies) protein.
REUL is an E3 ubiquitin ligase (show MUL1 Antibodies) of RIG-I (show DDX58 Antibodies) and specifically stimulates RIG-I (show DDX58 Antibodies)-mediated innate antiviral activity
These data identify RNF135 as causative of a new overgrowth syndrome and demonstrate that RNF135 haploinsufficiency contributes to the phenotype of NF1 (show NF1 Antibodies) microdeletion cases.
identify an alternative factor, Riplet/RNF135, that promotes RIG-I (show DDX58 Antibodies) activation independent of TRIM25 (show TRIM25 Antibodies)
RNF135 mutations are not present in patients with Sotos (show NSD1 Antibodies) syndrome-like features.
Riplet is essential for regulating RIG-I (show DDX58 Antibodies)-mediated innate immune response against RNA virus infection in vivo.
The protein encoded by this gene contains a RING finger domain, a motif present in a variety of functionally distinct proteins and known to be involved in protein-protein and protein-DNA interactions. This gene is located in a chromosomal region known to be frequently deleted in patients with neurofibromatosis. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
E3 ubiquitin-protein ligase RNF135
, RIG-I E3 ubiquitin ligase
, U 2-3-0