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anti-Ring Finger Protein 168 (RNF168) Antibodies

RNF168 encodes an E3 ubiquitin ligase protein that contains a RING finger, a motif present in a variety of functionally distinct proteins and known to be involved in protein-DNA and protein-protein interactions. Additionally we are shipping RNF168 Proteins (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
RNF168 70238 Q80XJ2
RNF168 165918 Q8IYW5
RNF168 690043 B2RYR0
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Top anti-RNF168 Antibodies at antibodies-online.com

Showing 10 out of 57 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of RNF168 in human brain tissue lysate with this product at 1 μg/ml. 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Chicken Rabbit Un-conjugated IHC, WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC, WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated WB RNF168 Antibody (C-term)  western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the RNF168 antibody detected the RNF168 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated IF, WB Immunofluorescence of monoclonal antibody to RNF168 on HepG2 cell (antibody concentration 10 µg/mL). RNF168 monoclonal antibody (M01), clone 3E1 Western Blot analysis of RNF168 expression in HepG2. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Dog Rabbit Un-conjugated IHC, ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated ELISA, WB 100 μg Log in to see 8 to 10 Days
$522.50
Details
Human Rabbit Un-conjugated IHC, WB RNF168 antibody was used for immunohistochemistry at a concentration of 4-8 ug/ml to stain Neural cells (arrows) in Human Brain. Magnification is at 400X RNF168 antibody was used for immunohistochemistry at a concentration of 4-8 ug/ml. Magnification is at 400X 50 μg Log in to see 3 to 4 Days
$473.93
Details
Human Mouse Un-conjugated IF, IHC (p), ELISA, WB 100 μg Log in to see 8 to 10 Days
$537.17
Details
Human Rabbit Alkaline Phosphatase (AP) ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details

RNF168 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine)
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Human ,
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Rat (Rattus)


Top referenced anti-RNF168 Antibodies

  1. Human Polyclonal RNF168 Primary Antibody for EIA, WB - ABIN500624 : Doil, Mailand, Bekker-Jensen, Menard, Larsen, Pepperkok, Ellenberg, Panier, Durocher, Bartek, Lukas, Lukas: RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins. in Cell 2009 (PubMed)

More Antibodies against RNF168 Interaction Partners

Mouse (Murine) Ring Finger Protein 168 (RNF168) interaction partners

  1. RNF168, in complex with RAD6A (show ube2a Antibodies) or RAD6B (show UBE2B Antibodies), is activated in the DNA-damage-induced protein ubiquitination cascade.

  2. Rnf168 is important for maintaining genomic integrity, and it cooperates with p53 (show TP53 Antibodies) in suppressing tumorigenesis.

Human Ring Finger Protein 168 (RNF168) interaction partners

  1. Results reveal an important role of USP7 (show USP7 Antibodies) in regulating ubiquitin-dependent signaling via stabilization of RNF168.

  2. CK2 (show CSNK2A1 Antibodies)/WIP1 (show PPM1D Antibodies)-mediated modulation of LSD1 (show KDM1A Antibodies) phosphorylation facilitates RNF168-dependent ubiquitination and recruitment of 53BP1 (show TP53BP1 Antibodies) to the DNA damage sites.

  3. The ubiquitin ligase RNF168 is strictly dependent on the activity that UbK27 is required to promote chromatin ubiquitination following DNA damage.

  4. Finding that RNF8 (show RNF8 Antibodies) is less abundant than RNF168 identifies RNF8 (show RNF8 Antibodies) as a rate-limiting determinant of focal repair complex assembly

  5. Depletion of RNF8 (show RNF8 Antibodies) or RNF168 blocks the degradation of diffusely localized nuclear 53BP1 (show TP53BP1 Antibodies).

  6. The E3 ligase RNF168 promotes both H2A ubiquitylation and neddylation. RNF168 is itself a substrate for NEDD8, and neddylation of RNF168 is necessary for its E3 ubiquitin activity.

  7. The acidic patch functions within the nucleosome as nucleosomes containing a mutated acidic patch exhibit defective H2A/H2AXub by RNF168 and RING1B (show RNF2 Antibodies)/BMI1 (show BMI1 Antibodies) in vitro

  8. Taken together, the results suggested that USP3 (show USP3 Antibodies) is a negative regulator of ubiquitination signaling, counteracting RNF168- and RNF8 (show RNF8 Antibodies)-mediated ubiquitination

  9. Before their localization to DNA double strand breaks, RNF168 interacts with 53BP1 and modifies it through the addition of a chain of ubiquitin-polypeptides.

  10. RNF168 physically interacts with LSD1 (show KDM1A Antibodies) and we find this interaction to be important for LSD1 (show KDM1A Antibodies) recruitment to DNA damage sites.

RNF168 Antigen Profile

Protein Summary

This gene encodes an E3 ubiquitin ligase protein that contains a RING finger, a motif present in a variety of functionally distinct proteins and known to be involved in protein-DNA and protein-protein interactions. The protein is involved in DNA double-strand break (DSB) repair. Mutations in this gene result in Riddle syndrome.

Gene names and symbols associated with RNF168

  • ring finger protein 168 (Rnf168) antibody
  • ring finger protein 168, E3 ubiquitin protein ligase (rnf168) antibody
  • ring finger protein 168, E3 ubiquitin protein ligase (RNF168) antibody
  • ring finger protein 168, E3 ubiquitin protein ligase (Rnf168) antibody
  • 3110001H15Rik antibody
  • hRNF168 antibody

Protein level used designations for RNF168

E3 ubiquitin-protein ligase RNF168 , ring fnger protein 168

GENE ID SPECIES
70238 Mus musculus
432198 Xenopus laevis
770166 Gallus gallus
165918 Homo sapiens
488029 Canis lupus familiaris
613812 Bos taurus
690043 Rattus norvegicus
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