Ring Finger Protein 43 Proteins (RNF43)

RNF43 is a HAP95 (AKAP8L\; MIM 609475) binding ubiquitin ligase that promotes cell growth and is upregulated in colon cancer (Yagyu et al., 2004 [PubMed 15492824]\; Sugiura et al., 2008 [PubMed 18313049]).[supplied by OMIM, Dec 2008].. Additionally we are shipping RNF43 Antibodies (28) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
RNF43 54894 Q68DV7
RNF43 207742 Q5NCP0
Rat RNF43 RNF43 303412  
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Top RNF43 Proteins at antibodies-online.com

Showing 6 out of 8 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$4,331.68
Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$7,759.50
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$4,331.68
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 60 to 65 Days
$6,052.17
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HOST_Human Cells Human Fc Tag 100 μg Log in to see 20 to 21 Days
$382.80
Details
HOST_Human Cells Human His tag 100 μg Log in to see 20 to 21 Days
$382.80
Details

RNF43 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
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Mouse (Murine) ,
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More Proteins for Ring Finger Protein 43 (RNF43) Interaction Partners

Human Ring Finger Protein 43 (RNF43) interaction partners

  1. Chimeric transcript resulting from the fusion of RNF43 and SUPT4H1 (show SUPT4H1 Proteins) was found to occur frequently in primary colorectal carcinoma.

  2. RNF43 mutation constitutes an important mutated driver gene for the Serrated Neoplasia pathway in both the sporadic and familial Polyposis settings.

  3. RNF43 is down-regulated in intrahepatic cholangiocarcinoma and may play a crucial role during development of ICC.

  4. The finding of RNF43 mutation in sessile serrated adenoma and traditional serrated adenoma, but not in tubulovillous/villous adenoma, indicated that RNF43 mutation is an early and specific molecular aberration in the serrated colorectal carcinoma pathway.

  5. Mutations and downregulation of RNF43 may play a critical role in the transition from adenoma to carcinoma.

  6. PTPRK (show PTPRK Proteins)-RSPO3 (show RSPO3 Proteins) fusions and RNF43 mutations were found to be characteristic genetic features of traditional serrated adenomas (TSAs).

  7. our study exhibited the expression patterns and correlation of RNF43 and p53 (show TP53 Proteins) pathway proteins involved in cell cycling

  8. Authors also identified ring finger (show PCGF1 Proteins) 43 (RNF43), an inhibitor of Wnt (show WNT2 Proteins)/beta-catenin (show CTNNB1 Proteins) signaling, as a target of miR (show MLXIP Proteins)-550a-5p.

  9. RNF43 inhibits the Wnt (show WNT2 Proteins) pathway downstream of oncogenic mutations that activate the pathway.

  10. RNF43 might act as a tumor suppressor in gastric carcinoma and might be a potential indicator for the clinical assessment of gastric cancer prognosis

Mouse (Murine) Ring Finger Protein 43 (RNF43) interaction partners

  1. RSPO (show RSPO1 Proteins)-LGR4 (show LGR4 Proteins)/5-ZNRF3 (show ZNRF3 Proteins)/RNF43 module controls metabolic liver zonation and is a hepatic growth/size rheostat during development, homeostasis and regeneration.

  2. RNF43 and ZNRF3 (show ZNRF3 Proteins) reduce Wnt (show WNT2 Proteins) signals by selectively ubiquitinating frizzled receptors, thereby targeting these Wnt (show WNT2 Proteins) receptors for degradation

RNF43 Protein Profile

Protein Summary

RNF43 is a HAP95 (AKAP8L\; MIM 609475) binding ubiquitin ligase that promotes cell growth and is upregulated in colon cancer (Yagyu et al., 2004

Gene names and symbols associated with Ring Finger Protein 43 Proteins (RNF43)

  • ring finger protein 43 (RNF43)
  • ring finger protein 43 (Rnf43)
  • 4732452J19Rik protein
  • RGD1305204 protein
  • RNF124 protein
  • URCC protein

Protein level used designations for Ring Finger Protein 43 Proteins (RNF43)

E3 ubiquitin-protein ligase RNF43 , RING finger protein 43

GENE ID SPECIES
100057001 Equus caballus
54894 Homo sapiens
491114 Canis lupus familiaris
784035 Bos taurus
207742 Mus musculus
303412 Rattus norvegicus
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