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S100 Calcium Binding Protein A4 Proteins (S100A4)

The protein encoded by S100A4 is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. Additionally we are shipping s100a4 Antibodies (136) and s100a4 Kits (21) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
S100A4 6275 P26447
S100A4 20198 P07091
S100A4 24615 P05942
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Top s100a4 Proteins at antibodies-online.com

Showing 10 out of 36 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Human Cells Human Fc Tag 100 μg Log in to see 16 Days
$382.80
Details
HOST_Human Cells Mouse Fc Tag 100 μg Log in to see 16 Days
$382.80
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 16 Days
$382.80
Details
HOST_Escherichia coli (E. coli) Mouse His tag 100 μg Log in to see 16 Days
$382.80
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag 100 μg Log in to see 7 to 8 Days
$319.00
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 7 to 8 Days
$319.00
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag   10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Mouse His tag 100 μg Log in to see 11 to 13 Days
$633.60
Details

S100A4 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, , ,
Mouse (Murine) ,
,
Rat (Rattus)

Top referenced s100a4 Proteins

  1. Mouse (Murine) s100a4 Protein expressed in Human Cells - ABIN2007870 : Ambartsumian, Tarabykina, Grigorian, Tulchinsky, Hulgaard, Georgiev, Lukanidin: Characterization of two splice variants of metastasis-associated human mts1 gene. in Gene 1995 (PubMed)
    Show all 7 references for ABIN2007870

  2. Human s100a4 Protein expressed in Human Cells - ABIN2002274 : Helfman, Kim, Lukanidin, Grigorian: The metastasis associated protein S100A4: role in tumour progression and metastasis. in British journal of cancer 2005 (PubMed)
    Show all 6 references for ABIN2002274

  3. Mouse (Murine) s100a4 Protein expressed in Escherichia coli (E. coli) - ABIN2007872 : Saleem, Kweon, Johnson, Adhami, Elcheva, Khan, Bin Hafeez, Bhat, Sarfaraz, Reagan-Shaw, Spiegelman, Setaluri, Mukhtar: S100A4 accelerates tumorigenesis and invasion of human prostate cancer through the transcriptional regulation of matrix metalloproteinase 9. in Proceedings of the National Academy of Sciences of the United States of America 2006 (PubMed)
    Show all 6 references for ABIN2007872

  4. Human s100a4 Protein expressed in Escherichia coli (E. coli) - ABIN2002276 : Marenholz, Heizmann, Fritz: S100 proteins in mouse and man: from evolution to function and pathology (including an update of the nomenclature). in Biochemical and biophysical research communications 2004 (PubMed)
    Show all 5 references for ABIN2002276

  5. Mouse (Murine) s100a4 Protein expressed in Escherichia coli (E. coli) - ABIN667465 : Sherbet: Metastasis promoter S100A4 is a potentially valuable molecular target for cancer therapy. in Cancer letters 2009 (PubMed)
    Show all 2 references for ABIN667465

  6. Human s100a4 Protein expressed in Wheat germ - ABIN1319061 : Mencía, Selga, Rico, de Almagro, Villalobos, Ramirez, Adan, Hernández, Noé, Ciudad: Overexpression of S100A4 in human cancer cell lines resistant to methotrexate. in BMC cancer 2010 (PubMed)
    Show all 2 references for ABIN1319061

More Proteins for S100 Calcium Binding Protein A4 (S100A4) Interaction Partners

Human S100 Calcium Binding Protein A4 (S100A4) interaction partners

  1. Study shows that negative expression of S100A4 was significantly associated with higher 3-year OS rate and N0 stage for lymph node metastasis in pancreatic neoplasm tumor which suggest that S100A4 expression represents a potential marker for lymph node metastasis and a potential unfavorable factor for prognosis of patients with this disease.

  2. S100A4 mRNA level is an important molecular biomarker for prediction of chemosensitivity to gemcitabine in unresectable pancreatic cancer.

  3. Tag7-Mts1 complex causes chemotactic migration of lymphocytes, with NK cells being a preferred target.

  4. our data suggest a novel mechanism for mutant p53V143A accumulation and add a new facet to the role of S100A4 in cancer

  5. S100A4 levels are elevated in human periodontal ligament cells in response to IL-1beta (show IL1B Proteins).

  6. Enhanced S100A4 expression was observed in remodeled intrapulmonary arteries of COPD patients.

  7. Downregulation of AKT3 (show AKT3 Proteins) increases migration and metastasis in triple negative breast cancer cells by upregulating S100A4.

  8. vimentin (show VIM Proteins) and FSP1 have roles in gingival fibrosis

  9. Through selective knockout or inhibition of the network components, we show that the interaction between epidermal growth factor receptor (EGFR (show EGFR Proteins)) and S100A4 modulates the sensitivity of angiogenesis development to matrix metalloproteinases (MMPs) activity

  10. The results show that S100A4 enhances the activity of matrix metalloproteinases (MMPs), causing higher cell dissociation. Moreover, it leads to an increased stability of the pathological state.

Mouse (Murine) S100 Calcium Binding Protein A4 (S100A4) interaction partners

  1. Our results indicated that RNV was ameliorated by Ad-S100A4-RNAi transfer in a mouse model of OIR through mediation of the anti-apoptotic effect of Bcl-2 (show BCL2 Proteins) by reducing the expression of CREB (show CREB1 Proteins).

  2. The thymic CD45 (show PTPRC Proteins)-FSP1+ cells are a subpopulation of fibroblasts, which is crucial for the maintenance and regeneration of thymic epithelial cells.

  3. Enhanced S100A4 expression was observed in remodeled intrapulmonary arteries of mice with smoke-induced emphysema.

  4. Downregulation of AKT3 (show AKT3 Proteins) increases migration and metastasis in triple negative breast cancer cells by upregulating S100A4.

  5. S100A4 promotes liver fibrosis by activating HSCs, which may represent a potential target for anti-fibrotic therapies.

  6. The S100A4 blocking antibody (6B12) reduces tumor growth and metastasis in a model of spontaneous breast cancer.

  7. Functional studies of human TH2 cells as well as mouse models of allergy showed that deletion of one of the genes, S100A4, resulted in decreased signs of allergy.

  8. S100A4 in endothelial cells is involved in tube formation, and suggest its potential as a molecular target for inhibiting tumor angiogenesis

  9. S100A4 is overexpressed in an experimental head and neck squamous cell carcinoma, and its inhibition reduces tumor burden.

  10. interaction of macrophage-derived S100A4 with B16-F10 (show F10 Proteins) melanoma results in increased metastatic lung colonization in vivo

s100a4 (S100A4) Protein Profile

Protein Summary

The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in motility, invasion, and tubulin polymerization. Chromosomal rearrangements and altered expression of this gene have been implicated in tumor metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Gene names and symbols associated with S100A4

  • S100 calcium binding protein A4 (S100A4)
  • S100 calcium-binding protein A4 (LOC100349003)
  • S100 calcium binding protein A4 (S100a4)
  • S100 calcium-binding protein A4 (S100a4)
  • 18A2 protein
  • 42a protein
  • Capl protein
  • FSp1 protein
  • metastasin protein
  • Mts1 protein
  • P9ka protein
  • PeL98 protein
  • pk9a protein
  • RNP9KA protein
  • S100A4 protein

Protein level used designations for S100A4

S100 calcium binding protein A4 , S100 calcium-binding protein A4 , S100 calcium-binding protein A4 (calcium protein, calvasculin, metastasin, murine placental homolog) , fibroblast-specific protein-1 , leukemia multidrug resistance associated protein , malignant transformation suppression 1 , placental calcium-binding protein , protein Mts1 , protein S100-A4 , S100 calcium binding protein A4 (calcium protein, calvasculin, metastasin, murine placental homolog) , metastasin , S100 calcium-binding protein A4 (calcium protein,calvasculin, metastasin, murine placental homolog) , placental calcium-binding protein homolog , calvasculin , metastatic cell protein , protein 18A2 , P9K , Protein 9 Ka homologous to calcium-binding protein , nerve growth factor-induced protein 42A

GENE ID SPECIES
457320 Pan troglodytes
715115 Macaca mulatta
100349003 Oryctolagus cuniculus
6275 Homo sapiens
403787 Canis lupus familiaris
101083141 Felis catus
282343 Bos taurus
20198 Mus musculus
100723950 Cavia porcellus
24615 Rattus norvegicus
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