s100a4 Protein (His tag)

Catalog No. ABIN7319483

Product Details

Target: s100a4 (S100A4) (S100 Calcium Binding Protein A4 (S100A4))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This s100a4 protein is labelled with His tag.

Purpose: Recombinant Human S100A4 Protein (His Tag)

Sequence: Met1-Lys101

Characteristics: Recombinant Human S100A4 is produced by our E.coli expression system and the target gene encoding Met1-Lys101 is expressed with a 6His tag at the C-terminus.

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin Level: < 1.0 EU per μg as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: s100a4 (S100A4) (S100 Calcium Binding Protein A4 (S100A4))

Alternative Name: S100A4 (S100A4 Products)

Synonyms: 18A2 Protein, 42A Protein, CAPL Protein, FSP1 Protein, MTS1 Protein, P9KA Protein, PEL98 Protein, 42a Protein, Capl Protein, FSp1 Protein, Mts1 Protein, PeL98 Protein, metastasin Protein, pk9a Protein, S100A4 Protein, P9ka Protein, RNP9KA Protein, S100 calcium binding protein A4 Protein, S100 calcium-binding protein A4 Protein, S100A4 Protein, S100a4 Protein

Background:

Background: S100A4 is a member of the S100 family of proteins. The S100 family is further classified as a member of the EF-hand superfamily of Ca++-binding proteins. These participate in both calcium-dependent and calcium-independent protein-protein interactions. The hallmark of this superfamily is the EF-hand motif that consists of a Ca++-binding site flanked by two α-helices (helix E and helix F) that were originally identified in a right-handed model of carp muscle calcium-binding protein. Human S100A4 is 101 amino acids (aa) in length. It contains two EF hand domains, one between aa 12-47, and a second between aa 50-85. S100A4 activity has been associated with cell transformation. It seems likely this is either coincidental, or a consequence, rather than a cause of transformation.

Synonym: Protein S100-A4, Calvasculin, Metastasin, Placental calcium-binding protein, Protein Mts1, S100 calcium-binding protein A4, S100A4, CAPL, MTS1,18A2,42A,FSP1,P9KA,PEL98

Molecular Weight: 12.6 kDa

UniProt: P26447

Pathways: S100 Proteins