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anti-SIN3 Transcription Regulator Homolog A (Yeast) (SIN3A) Antibodies

The protein encoded by SIN3A is a transcriptional regulatory protein. Additionally we are shipping SIN3A Proteins (4) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SIN3A 25942 Q96ST3
SIN3A 363067  
SIN3A 20466 Q60520
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Top anti-SIN3A Antibodies at antibodies-online.com

Showing 10 out of 50 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated IHC, WB WB Suggested Anti-SIN3A Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: Hela cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Mouse Rabbit Un-conjugated WB Mouse Sin3a Antibody (C-term)  western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).This demonstrates the Sin3a antibody detected the Sin3a protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p), WB Human Placenta (formalin-fixed, paraffin-embedded) stained with SIN3A antibody ABIN462178 followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Human Kidney (formalin-fixed, paraffin-embedded) stained with SIN3A antibody ABIN462178 followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 8 to 10 Days
$676.50
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated IF, IHC, WB 100 μL Log in to see 14 Days
$369.79
Details
Human Rabbit Un-conjugated ChIP, WB SIN3A antibody (pAb) tested by ChIP. Chromatin immunoprecipitation (ChIP) was performed using the ChIP-IT® High Sensitivity Kit (Cat. No. 53040) with 30 µg of chromatin from TM4 Sertoli cells and 5 µl of SIN3A antibody. ChIP DNA was used in qPCR with the control primer pairs or gene-specific primer pairs as indicated. Data are presented as Binding Events Detected per 1000 Cells using Active Motif's Epigenetic Services normalization scheme which accounts for primer efficiency and the amount of chromatin used in the ChIP reaction. SIN3A antibody (pAb) tested by Western blot. Nuclear extract of HeLa cells (20 μg) probed with SIN3A antibody at a dilution of 1:5,000. 100 μL Log in to see 1 to 2 Days
$466.67
Details
Mouse Rabbit Un-conjugated ICC, IP, IHC (p), WB Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE) 100 μL Log in to see 8 to 10 Days
$676.50
Details
Mouse Rabbit Alkaline Phosphatase (AP) ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Mouse Un-conjugated ELISA, WB Detection limit for recombinant GST tagged SIN3A is 0.03 ng/ml as a capture antibody. Western Blot detection against Immunogen (36.63 KDa) . 100 μg Log in to see 9 Days
$430.00
Details
Mouse Rabbit Un-conjugated WB 400 μL Log in to see 6 Days
$457.14
Details

SIN3A Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , , , ,
, ,
,
Rat (Rattus)


Mouse (Murine) , ,
,

, , , , ,

Top referenced anti-SIN3A Antibodies

  1. Chicken Polyclonal SIN3A Primary Antibody for IHC, WB - ABIN2779673 : Zhao, Jankovic, Gural, Huang, Pardanani, Menendez, Zhang, Dunne, Xiao, Erdjument-Bromage, Allis, Tempst, Nimer: Methylation of RUNX1 by PRMT1 abrogates SIN3A binding and potentiates its transcriptional activity. in Genes & development 2008 (PubMed)

More Antibodies against SIN3A Interaction Partners

Human SIN3 Transcription Regulator Homolog A (Yeast) (SIN3A) interaction partners

  1. Two novel translocations leading to the inactivation of RUNX1 (show RUNX1 Antibodies) and its partners SIN3A and TCF12 (show TCF12 Antibodies) in myeloid leukemia (show BCL11A Antibodies).

  2. Study suggests a lack of association of SIN3A gene sequence variants with azoospermia caused by Sertoli cell-only syndrome in humans.

  3. down regulation of miR (show MLXIP Antibodies)-202 increased the expression of its target Mxd1 (show MXD1 Antibodies), followed by Mxd1 (show MXD1 Antibodies) recruitment to the Sin3A repressor complex and through its dimerization with Max, and increased repression of Myc (show MYC Antibodies)-Max target proteins.

  4. protein pairs significantly correlated with an increased risk of death in non-small cell lung cancer: mSin3A with p16 (show CDKN2A Antibodies), and c-Myc (show MYC Antibodies) with mSinA

  5. Aberrantly expressed miR (show MLXIP Antibodies)-210 regulates human U251 glioma cells apoptosis and proliferation partly through directly down-regulating SIN3A protein expression.

  6. Bone-marrow-specific deletion of Sin3a, indicated that Sin3a-associated HDAC1/2-activity is essential for hematopoietic stem cell homeostasis.

  7. SIN3A, generally regarded as a transcriptional repressor, is required for induction of gene transcription by the aryl hydrocarbon receptor (show AHR Antibodies).

  8. EBNA3C binds strongly to BATF/IRF4 (show IRF4 Antibodies)/SPI1 (show SPI1 Antibodies)/RUNX3 (show RUNX3 Antibodies) sites to enhance transcription and recruits RBPJ (show RBPJ Antibodies)/Sin3A- and REST/NRSF-repressive complexes to repress p14(ARF (show CDKN2A Antibodies)) and p16(INK4A (show CDKN2A Antibodies)) expression

  9. BIM (show BCL2L11 Antibodies) silencing in anaplastic large cell lymphoma occurs through recruitment of MeCP2 (show MECP2 Antibodies) and the SIN3a/histone deacetylase 1/2 corepressor complex.

  10. reducing Sin3A strongly increased the invasive behavior of A549 human lung adenocarcinoma cells; findings show that Sin3A is downregulated in a variety of human tumors

Mouse (Murine) SIN3 Transcription Regulator Homolog A (Yeast) (SIN3A) interaction partners

  1. Sin3a mRNA is recruited during maturation and that inhibiting its recruitment not only inhibits development beyond the 2-cell stage but also compromises the fidelity of reprogramming gene expression

  2. Report role of myocardial mSin3A/HDAC1 (show HDAC1 Antibodies)/2 complex in mediating the beneficial effects of exercise in diabetic cardiomyopathy.

  3. SIN3A, generally regarded as a transcriptional repressor, is required for induction of gene transcription by the aryl hydrocarbon receptor (show AHR Antibodies).

  4. Treatment with GlcN, in contrast, inhibits LPS (show TLR4 Antibodies)-ind inflammation and decreased LPS (show TLR4 Antibodies)-mediated recruitment of OGT (show OGT Antibodies), mSin3A, and HDACs.

  5. Within the male germline, Sin3a is required for the mitotic reentry of gonocytes, but is dispensable for the maintenance of differentiating spermatogonia and subsequent spermatogenic processes.

  6. Sin3A-deleted testes exhibit a Sertoli-cell only phenotype, consistent with the absolute requirement for Sin3A in germ cells' development and/or viability.

  7. Sin3 has an important role in the regulation of cell cycle kinetics of the myogenic progenitor cell population

  8. ARID4B (show ARID4B Antibodies) physically interacts with the breast cancer metastasis suppressor BRMS1 (show BRMS1 Antibodies), and we detected differential binding of the Arid4b (show ARID4B Antibodies) alleles to mSIN3A and mSDS3 (show SUDS3 Antibodies)

  9. Results indicate that Sin3a protects the genomic integrity of pluripotent embryonic cells and governs their unusual cell cycle.

  10. Sin3a causes deacetylation of c-Myc (show MYC Antibodies) protein to directly repress c-Myc (show MYC Antibodies) activity.

SIN3A Antigen Profile

Protein Summary

The protein encoded by this gene is a transcriptional regulatory protein. It contains paired amphipathic helix (PAH) domains, which are important for protein-protein interactions and may mediate repression by the Mad-Max complex.

Gene names and symbols associated with SIN3A

  • SIN3 transcription regulator homolog A (yeast) (SIN3A) antibody
  • SIN3 homolog A, transcription regulator (yeast) (SIN3A) antibody
  • SIN3 transcription regulator family member A (SIN3A) antibody
  • SIN3 transcription regulator homolog A (yeast) (Sin3a) antibody
  • transcriptional regulator, SIN3A (yeast) (Sin3a) antibody
  • AW553200 antibody
  • mKIAA4126 antibody
  • mSin3A antibody
  • Sin3 antibody

Protein level used designations for SIN3A

SIN3 homolog A, transcription regulator , transcriptional co-repressor Sin3A , paired amphipathic helix protein Sin3a , SIN3 homolog A, transcription regulator (yeast) , paired amphipathic helix protein Sin3a-like , SIN3 transcription regulator homolog A , histone deacetylase complex subunit Sin3a , transcriptional corepressor Sin3a , transcriptional regulator, SIN3A , transcriptional regulator, SIN3 yeast homolog A

GENE ID SPECIES
453759 Pan troglodytes
478372 Canis lupus familiaris
518504 Bos taurus
705719 Macaca mulatta
100404916 Callithrix jacchus
100477344 Ailuropoda melanoleuca
100641919 Amphimedon queenslandica
25942 Homo sapiens
415307 Gallus gallus
363067 Rattus norvegicus
20466 Mus musculus
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