SIN3A antibody (C-Term)
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- Target See all SIN3A Antibodies
- SIN3A (SIN3 homolog A, transcription regulator (SIN3A))
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Binding Specificity
- AA 1078-1106, C-Term
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Reactivity
- Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SIN3A antibody is un-conjugated
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Application
- Western Blotting (WB)
- Predicted Reactivity
- H
- Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This Mouse Sin3a antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1078-1106 amino acids from the C-terminal region of mouse Sin3a.
- Clone
- RB40011
- Isotype
- Ig Fraction
- Top Product
- Discover our top product SIN3A Primary Antibody
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- Application Notes
- WB: 1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Mouse Sin3a Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
- Expiry Date
- 6 months
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- Target
- SIN3A (SIN3 homolog A, transcription regulator (SIN3A))
- Alternative Name
- Sin3a (SIN3A Products)
- Synonyms
- AW553200 antibody, Sin3 antibody, mKIAA4126 antibody, mSin3A antibody, zgc:162128 antibody, SIN3A antibody, SIN3 transcription regulator family member A antibody, transcriptional regulator, SIN3A (yeast) antibody, paired amphipathic helix protein Sin3a antibody, SIN3 transcription regulator family member Aa antibody, SIN3A antibody, Sin3a antibody, LOC100641919 antibody, sin3aa antibody, LOC100439524 antibody
- Background
- Sin3a acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Also interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3A to DNA. Acts as a corepressor for REST.
- Molecular Weight
- 145088
- Gene ID
- 20466
- NCBI Accession
- NP_001103820, NP_001103821, NP_035508
- UniProt
- Q60520
- Pathways
- Activation of Innate immune Response, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha
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