Sclerostin (SOST) ELISA Kits

Sclerostin is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain and sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. Additionally we are shipping Sclerostin Antibodies (128) and Sclerostin Proteins (18) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
SOST 50964 Q9BQB4
SOST 74499 Q99P68
SOST 80722 Q99P67
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top Sclerostin ELISA Kits at antibodies-online.com

Showing 10 out of 63 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.113 ng/mL 0.31 ng/mL - 20 ng/mL 96 Tests Log in to see 13 to 16 Days
$589.47
Details
Mouse 2.79 pg/mL 6.25 pg/mL - 400 pg/mL 96 Tests Log in to see 13 to 16 Days
$606.32
Details
Rat 32 pg/mL 78 pg/mL - 5000 pg/mL 96 Tests Log in to see 13 to 16 Days
$640.00
Details
Cow 15.63 pg/mL   96 Tests Log in to see 15 to 18 Days
$1,026.67
Details
Human 0.113 ng/mL 0.312 ng/mL - 20 ng/mL   96 Tests Log in to see 8 to 12 Days
$766.25
Details
Mouse 2.79 pg/mL 6.25 pg/mL - 400 pg/mL   96 Tests Log in to see 8 to 12 Days
$787.25
Details
Rabbit 0.1 ng/mL 0.5-10 ng/mL   96 Tests Log in to see 15 to 18 Days
$707.14
Details
Guinea Pig 0.1 ng/mL 0.5-10 ng/mL   96 Tests Log in to see 15 to 18 Days
$707.14
Details
Monkey 0.1 ng/mL 1.0-25 ng/mL   96 Tests Log in to see 15 to 18 Days
$707.14
Details
Dog 0.1 ng/mL 0.5-10 ng/mL   96 Tests Log in to see 15 to 18 Days
$707.14
Details

Top referenced Sclerostin ELISA Kits

  1. Human Sclerostin ELISA Kit for Sandwich ELISA - ABIN457071 : Cidem, Usta, Karacan, Kucuk, Uludag, Gun: Effects of sex steroids on serum sclerostin levels during the menstrual cycle. in Gynecologic and obstetric investigation 2013 (PubMed)
    Show all 5 Pubmed References

  2. Human Sclerostin ELISA Kit for Sandwich ELISA - ABIN415155 : Brabnikova Maresova, Pavelka, Stepan: Acute effects of glucocorticoids on serum markers of osteoclasts, osteoblasts, and osteocytes. in Calcified tissue international 2013 (PubMed)
    Show all 3 Pubmed References

  3. Rat (Rattus) Sclerostin ELISA Kit for Sandwich ELISA - ABIN416496 : Kim, Lee, Jo, Song, Lim, Park, Bonewald, Kim: Exendin-4 increases bone mineral density in type 2 diabetic OLETF rats potentially through the down-regulation of SOST/sclerostin in osteocytes. in Life sciences 2013 (PubMed)
    Show all 2 Pubmed References

  4. Mouse (Murine) Sclerostin ELISA Kit for Sandwich ELISA - ABIN426039 : Yorgan, Peters, Jeschke, Benisch, Jakob, Amling, Schinke: The Anti-Osteoanabolic Function of Sclerostin Is Blunted in Mice Carrying a High Bone Mass Mutation of Lrp5. in Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2015 (PubMed)
    Show all 2 Pubmed References

  5. Rat (Rattus) Sclerostin ELISA Kit for Sandwich ELISA - ABIN585201 : Ferreira, Ferrari, Neves, Cavallari, Dominguez, Dos Reis, Graciolli, Oliveira, Liu, Sabbagh, Jorgetti, Schiavi, Moysés: Effects of dietary phosphate on adynamic bone disease in rats with chronic kidney disease--role of sclerostin? in PLoS ONE 2013 (PubMed)

More ELISA Kits for Sclerostin Interaction Partners

Human Sclerostin (SOST) interaction partners

  1. High serum levels of sclerostin and Dkk-1 (show DKK1 ELISA Kits) are associated with acute ischaemic stroke

  2. The increased expression of sclerostin in the liver and the association with histologic cholangitis may explain the high serum levels of this protein in patients with primary biliary cirrhosis.

  3. SOST silencing promotes the proliferation, invasion and migration, and decreases the apoptosis of human retinoblastoma cells by activating the Wnt (show WNT2 ELISA Kits)/beta-catenin (show CTNNB1 ELISA Kits) signaling pathway.

  4. Sclerostin concentrations in serum significantly decreased and IGF-I (show IGF1 ELISA Kits) significantly increased after 12months of resistance training or JUMP.

  5. observed an association between sclerostin levels with fasting insulin (show INS ELISA Kits) levels and homoeostatic model assessment-insulin (show INS ELISA Kits) resistance, but there was no clear association with type 2 diabetes risk.

  6. Sclerostin levels in KTR are normal and influenced more by bone turnover than by eGFR (show EGFR ELISA Kits). Its involvement with other hormones of mineral homeostasis (FGF23 (show FGF23 ELISA Kits)/Klotho (show KL ELISA Kits) and Vitamin D) is part of the sophisticated cross-talk between bone and the kidney

  7. In chronic kidney disease, serum levels of the Wnt (show WNT2 ELISA Kits) inhibitors DKK1 (show DKK1 ELISA Kits) and sclerostin are unrelated, indicating different sites of origin and/ or different regulatory mechanisms. Sclerostin, as opposed to DKK1 (show DKK1 ELISA Kits), may qualify as a biomarker of chronic kidney disease-mineral and bone and mineral disorder (CKD-MBD (show DPEP1 ELISA Kits)), particularly in dialysis patients.

  8. Vitamin D receptor (show VDR ELISA Kits) agonism by paricalcitol causes a moderate increase in serum sclerostin in CKD patients, and this effect is modified by circulating pentosidine levels.

  9. SOST is frequently expressed in skeletal bone- and cartilage-forming tumors. The strong spatial correlation with bone formation and the in vitro expression patterns are in line with the known functions of SOST in nonneoplastic bone, as a feedback inhibitor on osteogenic differentiation.

  10. Intermittent compressive stress regulates Notch (show NOTCH1 ELISA Kits) receptor and target gene expression via the TGF-beta (show TGFB1 ELISA Kits) signaling pathway. Notch (show NOTCH1 ELISA Kits) signaling participates in TGF-beta (show TGFB1 ELISA Kits)-induced sclerostin expression in periodontal ligament cells.

Mouse (Murine) Sclerostin (SOST) interaction partners

  1. loss of BMP signaling specifically in osteocytes dramatically increases bone mass presumably through simultaneous inhibition of RANKL (show TNFSF11 ELISA Kits) and SOST, leading to osteoclast inhibition and Wnt (show WNT2 ELISA Kits) activation together.

  2. humanized Multiple Myeloma xenograft mouse model bearing human MM cells (NOD-SCID.CB17 male mice injected intravenously with 2.5 million of MM1 (show PFDN5 ELISA Kits).S-Luc-GFP cells) demonstrated significantly higher concentrations of mouse-derived sclerostin, suggesting a microenvironmental source of sclerostin.

  3. Protection From Glucocorticoid-Induced Osteoporosis by Anti-Catabolic Signaling in the Absence of Sost/Sclerostin

  4. Osteocyte-derived molecule sclerostin drives bone marrow adipogenesis.

  5. complete absence of sclerostin has only minor effects on chronic kidney disease-induced bone loss in mice.

  6. In mice, sclerostin deficiency hastened reparative dentinogenesis after pulp injury, suggesting that the inhibition of sclerostin may constitute a promising therapeutic strategy for improving the healing of damaged pulps.

  7. These data suggest that sclerostin plays an important role in the bone remodeling of tooth movement.

  8. Sclerostin inhibits angiotensin II-induced aortic aneurysm and atherosclerosis via wnt (show WNT2 ELISA Kits) signaling pathway inhibition.

  9. Analysis of SOST expression using large minigenes reveals the MEF2C (show MEF2C ELISA Kits) binding site in the evolutionarily conserved region (ECR5) enhancer mediates forskolin, but not 1,25-dihydroxyvitamin D3 or TGFbeta1 (show TGFB1 ELISA Kits) responsiveness.

  10. removal of sclerostin appears to modestly protect the alveolar bone from resorption in this experimental setting

Sclerostin (SOST) Antigen Profile

Antigen Summary

Sclerostin is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain and sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. Loss-of-function mutations in this gene are associated with an autosomal-recessive disorder, sclerosteosis, which causes progressive bone overgrowth. A deletion downstream of this gene, which causes reduced sclerostin expression, is associated with a milder form of the disorder called van Buchem disease.

Gene names and symbols associated with Sclerostin (SOST) ELISA Kits

  • sclerostin (LOC100313724) antibody
  • sclerostin (SOST) antibody
  • sclerostin (Sost) antibody
  • 5430411E23Rik antibody
  • CDD antibody
  • LOC100313724 antibody
  • VBCH antibody

Protein level used designations for Sclerostin (SOST) ELISA Kits

sclerostin , sclerosteosis

GENE ID SPECIES
100313724 Saccoglossus kowalevskii
50964 Homo sapiens
74499 Mus musculus
80722 Rattus norvegicus
490948 Canis lupus familiaris
100730713 Cavia porcellus
282880 Bos taurus
429784 Gallus gallus
101114123 Ovis aries
100513306 Sus scrofa
Selected quality suppliers for Sclerostin (SOST) ELISA Kits
Did you look for something else?