Sclerostin (SOST) ELISA Kits

Sclerostin is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain and sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. Additionally we are shipping Sclerostin Antibodies (100) and Sclerostin Proteins (18) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
SOST 50964 Q9BQB4
SOST 74499 Q99P68
SOST 80722 Q99P67
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Top Sclerostin ELISA Kits at antibodies-online.com

Showing 10 out of 54 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 7.8 pg/mL 31.25-2000 pg/mL Typical standard curve 96 Tests Log in to see 13 to 16 Days
$1,026.67
Details
Mouse 2.79 pg/mL 6.25-400 pg/mL 96 Tests Log in to see 13 to 16 Days
$606.32
Details
Rat 32 pg/mL 78-5.000 pg/mL 96 Tests Log in to see 13 to 16 Days
$640.00
Details
Cow 15.63 pg/mL 4000-62.5 pg/mL   96 Tests Log in to see 15 to 18 Days
$1,026.67
Details
Rabbit 0.1 ng/mL 0.5-10 ng/mL   96 Tests Log in to see 15 to 18 Days
$707.14
Details
Guinea Pig 0.1 ng/mL 0.5-10 ng/mL   96 Tests Log in to see 15 to 18 Days
$707.14
Details
Monkey 0.1 ng/mL 1.0-25 ng/mL   96 Tests Log in to see 15 to 18 Days
$707.14
Details
Dog 0.1 ng/mL 0.5-10 ng/mL   96 Tests Log in to see 15 to 18 Days
$707.14
Details
Pig
  96 Tests Log in to see 15 to 18 Days
$707.14
Details
Sheep
  96 Tests Log in to see 15 to 18 Days
$707.14
Details

Top referenced Sclerostin ELISA Kits

  1. Human Sclerostin ELISA Kit for Sandwich ELISA - ABIN457071 : Cidem, Usta, Karacan, Kucuk, Uludag, Gun: Effects of sex steroids on serum sclerostin levels during the menstrual cycle. in Gynecologic and obstetric investigation 2013 (PubMed)
    Show all 5 references for 457071

  2. Rat (Rattus) Sclerostin ELISA Kit for Sandwich ELISA - ABIN416496 : Kim, Lee, Jo, Song, Lim, Park, Bonewald, Kim: Exendin-4 increases bone mineral density in type 2 diabetic OLETF rats potentially through the down-regulation of SOST/sclerostin in osteocytes. in Life sciences 2013 (PubMed)
    Show all 2 references for 416496

  3. Mouse (Murine) Sclerostin ELISA Kit for Sandwich ELISA - ABIN426039 : Yorgan, Peters, Jeschke, Benisch, Jakob, Amling, Schinke: The Anti-Osteoanabolic Function of Sclerostin Is Blunted in Mice Carrying a High Bone Mass Mutation of Lrp5. in Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2015 (PubMed)
    Show all 2 references for 426039

More ELISA Kits for Sclerostin Interaction Partners

Human Sclerostin (SOST) interaction partners

  1. Intermittent compressive stress regulates Notch (show NOTCH1 ELISA Kits) receptor and target gene expression via the TGF-beta (show TGFB1 ELISA Kits) signaling pathway. Notch (show NOTCH1 ELISA Kits) signaling participates in TGF-beta (show TGFB1 ELISA Kits)-induced sclerostin expression in periodontal ligament cells.

  2. Dickkopf-1 (show DKK1 ELISA Kits) and sclerostin were never correlated with each other or with bone turnover markers patients with Paget's disease of bone. Sclerostin was positively correlated with age.

  3. These data suggest that sclerostin plays an important role in the bone remodeling of tooth movement.

  4. Circulating sclerostin and Dickkopf-1 (show DKK1 ELISA Kits) levels do not change across the menstrual cycle and do not demonstrate any relationship with estradiol in premenopausal women.

  5. SOST is expressed in the aorta and downregulated in human aortic aneurysms and atheros (show WNT2 ELISA Kits)clerosis, possibly because of epigenetic silencing.

  6. The level of sclerostin was higher in the female obstructive sleep apnea (OSA) patients than that in female controls. Further, in OSA women with cardiovascular comorbidities, sclerostin was higher than in women without such comorbidities. In men, there were no differences in the serum sclerostin level between the OSA and control subjects, nor was there any relationship with cardiovascular diseases.

  7. Knockdown of SOST in MG-63 cells increases osteogenesis and ratio of OPG/RANKL (show TNFSF11 ELISA Kits) in vitro

  8. The findings confirm that the human SOST gene and sclerostin expression can be considered to be directly 1,25-dihydroxyvitamin D-responsive in osteocytes.

  9. Our study highlighted the high serum levels of DKK-1 (show DKK1 ELISA Kits) and sclerostin in T1DM children and their relationship with altered glycemic control

  10. Sclerostin is an osteocyte marker that is strongly expressed in human woven and lamellar bone and mineralizing chondrocytes

Mouse (Murine) Sclerostin (SOST) interaction partners

  1. These data suggest that sclerostin plays an important role in the bone remodeling of tooth movement.

  2. Sclerostin inhibits angiotensin II-induced aortic aneurysm and atherosclerosis via wnt (show WNT2 ELISA Kits) signaling pathway inhibition.

  3. Analysis of SOST expression using large minigenes reveals the MEF2C (show MEF2C ELISA Kits) binding site in the evolutionarily conserved region (ECR5) enhancer mediates forskolin, but not 1,25-dihydroxyvitamin D3 or TGFbeta1 (show TGFB1 ELISA Kits) responsiveness.

  4. removal of sclerostin appears to modestly protect the alveolar bone from resorption in this experimental setting

  5. chronic TNFalpha (tumor necrosis factor alpha (show TNF ELISA Kits))-dependent arthritis, fibroblast-like synoviocytes constitute a major source of sclerostin and that either the lack of sclerostin or its antibody-mediated inhibition leads to an acceleration of rheumatoid arthritis (RA)-like disease.

  6. Data show that the phenotype of Notch (show NOTCH1 ELISA Kits) activation in osteocytes was prevented in matrix protein 1 (Dmp1 (show DMP1 ELISA Kits))-Cre;Rosa(Notch (show NOTCH1 ELISA Kits)) mice hemizygous for the Dmp1 (show DMP1 ELISA Kits)-sclerostin (SOST) transgene.

  7. Results found that sclerostin enhances adipocyte differentiation in 3T3-L1 cells and reduced TAZ (show TAZ ELISA Kits)-responsive transcriptional activity and TAZ (show TAZ ELISA Kits)-responsive gene expression, indicating a role for TAZ (show TAZ ELISA Kits) as a regulator of adipogenesis by sclerostin.

  8. Our results suggested that sclerostin could be expressed in the liver and sustained successfully at high levels in the blood by using the PhiC31 integrase system, leading to trabecular bone loss.

  9. Sclerostin depletion enhances tibial fracture healing.

  10. SOST gene is involved in the regulation of renal interstitial fibrosis (RIF) progression. In obstructive kidney injury, SOST gene deletion would probably enhance renal fibrogenic response and promote the progression of RIF.

Sclerostin (SOST) Antigen Profile

Antigen Summary

Sclerostin is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain and sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. Loss-of-function mutations in this gene are associated with an autosomal-recessive disorder, sclerosteosis, which causes progressive bone overgrowth. A deletion downstream of this gene, which causes reduced sclerostin expression, is associated with a milder form of the disorder called van Buchem disease.

Gene names and symbols associated with Sclerostin (SOST) ELISA Kits

  • sclerostin (LOC100313724) antibody
  • sclerostin (SOST) antibody
  • sclerostin (Sost) antibody
  • sclerostin-like (LOC100513306) antibody
  • 5430411E23Rik antibody
  • CDD antibody
  • LOC100313724 antibody
  • VBCH antibody

Protein level used designations for Sclerostin (SOST) ELISA Kits

sclerostin , sclerosteosis

GENE ID SPECIES
100313724 Saccoglossus kowalevskii
50964 Homo sapiens
74499 Mus musculus
80722 Rattus norvegicus
490948 Canis lupus familiaris
100730713 Cavia porcellus
282880 Bos taurus
429784 Gallus gallus
101114123 Ovis aries
100513306 Sus scrofa
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