anti-Secretory Leukocyte Peptidase Inhibitor (SLPI) Antibodies

SLPI encodes a secreted inhibitor which protects epithelial tissues from serine proteases. Additionally we are shipping SLPI Kits (39) and SLPI Proteins (20) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SLPI 6590 P03973
SLPI 20568 P97430
SLPI 84386  
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Top anti-SLPI Antibodies at antibodies-online.com

Showing 10 out of 104 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse Biotin EIA, IHC (fro), IHC (p), WB 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-SLPI Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: Human heart WB Suggested Anti-SLPI  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:1562500  Positive Control: Human heart 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated EIA, IHC (fro), IHC (p), IP, WB 0.1 mg Log in to see 6 to 8 Days
$654.50
Details
Mouse Rabbit Un-conjugated EIA, WB   0.1 mg Log in to see 12 to 15 Days
$375.38
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB   0.1 mg Log in to see 10 to 12 Days
$375.38
Details
Human Rabbit Un-conjugated WB SLPI Antibody (Center)  western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the SLPI antibody detected the SLPI protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
$412.50
Details
Human Rabbit Un-conjugated EIA, IP, WB   0.1 mg Log in to see 6 to 8 Days
$709.50
Details
Human Rabbit Un-conjugated ELISA, IHC (p), WB   100 μg Log in to see 4 to 6 Days
$357.50
Details
Human Goat Un-conjugated ELISA, IHC (p), Neut, WB Immunohistochemistry-Paraffin: SLPI Antibody [NBP1-40032] - Analysis of anti-SLPI antibody with human placenta at concentration 2.5 ug/ml. Immunohistochemistry-Paraffin: SLPI Antibody [NBP1-40032] - Analysis of anti-SLPI antibody with human small intestine at concentration 2.5 ug/ml. 0.05 mg Log in to see 7 to 9 Days
$447.56
Details

SLPI Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human ,
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Mouse (Murine)


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Rat (Rattus)
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Top referenced anti-SLPI Antibodies

  1. Human Monoclonal SLPI Primary Antibody for EIA, IHC (fro) - ABIN1105385 : Wingens, van Bergen, Hiemstra, Meis, van Vlijmen-Willems, Zeeuwen, Mulder, Kramps, van Ruissen, Schalkwijk: Induction of SLPI (ALP/HUSI-I) in epidermal keratinocytes. in The Journal of investigative dermatology 1999 (PubMed)
    Show all 6 references for 1105385

  2. Human Monoclonal SLPI Primary Antibody for EIA, IHC (fro) - ABIN1105383 : Aarbiou, van Schadewijk, Stolk, Sont, de Boer, Rabe, van Krieken, Mauad, Hiemstra: Human neutrophil defensins and secretory leukocyte proteinase inhibitor in squamous metaplastic epithelium of bronchial airways. in Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2004 (PubMed)
    Show all 5 references for 1105383

  3. Human Polyclonal SLPI Primary Antibody for EIA, IP - ABIN1105384 : Kramps, van Twisk, Klasen, Dijkman: Interactions among stimulated human polymorphonuclear leucocytes, released elastase and bronchial antileucoprotease. in Clinical science (London, England : 1979) 1988 (PubMed)

More Antibodies against SLPI Interaction Partners

Human Secretory Leukocyte Peptidase Inhibitor (SLPI) interaction partners

  1. we demonstrated that the oncogenic effect of SLPI may be due to protection of growth factor progranulin (show GRN Antibodies) from enzymatic cleavage or suppression of castration-resistant prostate cancer (CRPC)cell apoptosis independent of anti-protease activity of SLPI. These findings implicate SLPI as a potential biomarker of resistance to AR inhibition and therapeutic target for CRPC treatment

  2. Secretory leukocyte protease inhibitor mediates invasiveness of oral carcinoma cells.

  3. The results indicate that SERPINE2 (show SERPINE2 Antibodies) and SLPI play a significant role in the development of papillary thyroid cancer and imply that the evaluation of serum concentrations of both anticoagulant molecules may be considered as additional marker for the differentiation of malignancies during the preoperative diagnosis of patients with thyroid gland tumors.

  4. Bronchial epithelial cells have decreased SLPI expression in response to hypoxia.

  5. Ongoing herpes simplex virus infection and resultant downregulation of local levels of SLPI may impart a greater susceptibility for keratinocytes to human papillomavirus type 16 infection through the host cell receptor annexin A2 (show ANXA2 Antibodies).

  6. SLPI is an independent predictor for both OS and DSS (show NR0B1 Antibodies) and a relevant prognostic biomarker in OSCC.

  7. The elevations in cervical elafin (show PI3 Antibodies) and SLPI expression in the women with preterm delivery might reflect the local response to the pathogen invasion into the cervix preceding preterm labor.

  8. These results demonstrate that SLPI down-regulates pIgR (show PIGR Antibodies) expression through the NF-kappaB (show NFKB1 Antibodies) signaling pathway by inhibiting degradation of IkappaBbeta (show NFKBIB Antibodies) protein.

  9. Abnormal over-expression of SLPI in pancreatic cancer cells may be associated with the development of disease through its roles in promoting cancer cell survival and proliferation as well as anti-apoptosis.

  10. study identifies a distinct immune response in SA characterized by a dysregulated IFN-gamma (show IFNG Antibodies)/SLPI axis that affects lung function.

Mouse (Murine) Secretory Leukocyte Peptidase Inhibitor (SLPI) interaction partners

  1. Slpi(-/-) mice had impaired collagen gene expression but animals demonstrated minimal reduction in lung fibrosis compared with wild-type animals. These data suggest that enhanced proteolysis does not further enhance TGF-beta (show TGFB1 Antibodies) activation, and inhibits sustained Col1alpha1, Col3alpha1, and Col4alpha1 gene expression following lung injury.

  2. Data show that differentiative switches between bronchiolar progenitors and club cells are under the Nrf2 (show NFE2L2 Antibodies)-mediated control of SLPI and syndecan 4 (show SDC4 Antibodies).

  3. study identifies a distinct immune response in SA characterized by a dysregulated IFN-gamma (show IFNG Antibodies)/SLPI axis that affects lung function.

  4. Studied the function of Secretory Leukocyte Protease Inhibitor (SLPI) in odontoblast during mouse tooth development.

  5. Data show that the expression of several genes encoding salivary antimicrobial proteins, such as secretory leukocyte peptidase inhibitor (SLPI), S100A8 (show S100A8 Antibodies), and lactotransferrin (show LTF Antibodies), was reduced due to myeloid differentiation dactor 88 (MyD88 (show MYD88 Antibodies)) deficiency.

  6. a possible role for SLPI in enhancing the metastatic behavior of breast cancer cell line 4T1

  7. These studies define an important role for SLPI in innate and adaptive immunity and offer new insight into strategies for the use of this naturally occurring molecule in the modulation of infectious and inflammatory diseases.

  8. In experimental autoimmune encephalomyelitis, SLPI exerts potent pro-inflammatory actions by modulation of T-cell activity

  9. The results underscore the importance of SLPI as a modulator of specific immunity that can also function at peripheral sites under pathogenic pressure.

  10. SLPI has a role in wound healing and innate immunity

SLPI Antigen Profile

Protein Summary

This gene encodes a secreted inhibitor which protects epithelial tissues from serine proteases. It is found in various secretions including seminal plasma, cervical mucus, and bronchial secretions, and has affinity for trypsin, leukocyte elastase, and cathepsin G. Its inhibitory effect contributes to the immune response by protecting epithelial surfaces from attack by endogenous proteolytic enzymes\; the protein is also thought to have broad-spectrum anti-biotic activity.

Gene names and symbols associated with SLPI

  • secretory leukocyte peptidase inhibitor (SLPI) antibody
  • antileukoproteinase-like (LOC512548) antibody
  • secretory leukocyte peptidase inhibitor (Slpi) antibody
  • ALK1 antibody
  • ALP antibody
  • BLPI antibody
  • ckpi antibody
  • HUSI antibody
  • HUSI-I antibody
  • MATN4 antibody
  • MPI antibody
  • SLPI antibody
  • WAP4 antibody
  • WFDC4 antibody

Protein level used designations for SLPI

antileukoproteinase , matrilin 4 , secretory leukocyte peptidase inhibitor , HUSI-1 , WAP four-disulfide core domain protein 4 , mucus proteinase inhibitor , protease inhibitor WAP4 , secretory leukocyte protease inhibitor (antileukoproteinase) , seminal proteinase inhibitor , ALP , secretory leukocyte protease inhibitor

GENE ID SPECIES
504598 Bos taurus
711156 Macaca mulatta
740668 Pan troglodytes
100137514 Papio anubis
100137521 Pongo abelii
512548 Bos taurus
6590 Homo sapiens
20568 Mus musculus
84386 Rattus norvegicus
100722975 Cavia porcellus
396886 Sus scrofa
641306 Ovis aries
100127207 Canis lupus familiaris
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