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SELP encodes a 140 kDa protein that is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. Additionally we are shipping SELP Kits (108) and SELP Proteins (35) and many more products for this protein.
Showing 10 out of 357 products:
Human Monoclonal SELP Primary Antibody for FACS - ABIN1106511
Bevilacqua, Nelson: Selectins. in The Journal of clinical investigation 1993
Show all 13 references for ABIN1106511
Human Monoclonal SELP Primary Antibody for FACS, IHC (fro) - ABIN118767
Sopper, Stahl-Hennig, Demuth, Johnston, Dörries, ter Meulen: Lymphocyte subsets and expression of differentiation markers in blood and lymphoid organs of rhesus monkeys. in Cytometry 1998
Show all 13 references for ABIN118767
Cat (Feline) Monoclonal SELP Primary Antibody for FACS, IHC (fro) - ABIN259995
Johnson, Wearden, Kocyildirim, Maul, Woolley, Ye, Strickler, Borovetz, Wagner: Platelet activation in ovines undergoing sham surgery or implant of the second generation PediaFlow pediatric ventricular assist device. in Artificial organs 2011
Show all 8 references for ABIN259995
Goat Monoclonal SELP Primary Antibody for FACS - ABIN120299
Massaguer, Engel, Pérez-del-Pulgar, Bosch, Pizcueta: Production and characterization of monoclonal antibodies against conserved epitopes of P-selectin (CD62P). in Tissue antigens 2001
Show all 5 references for ABIN120299
Human Polyclonal SELP Primary Antibody for IHC, WB - ABIN223314
He, Horuk, Moochhala, Bhatia: Treatment with BX471, a CC chemokine receptor 1 antagonist, attenuates systemic inflammatory response during sepsis. in American journal of physiology. Gastrointestinal and liver physiology 2007
Show all 4 references for ABIN223314
Human Polyclonal SELP Primary Antibody for IF (p), IHC (p) - ABIN670131
Ma, Niu, Sun, Wang, Luo, Zhang, Wang: Inflammatory responses induced by fluoride and arsenic at toxic concentration in rabbit aorta. in Archives of toxicology 2012
Show all 3 references for ABIN670131
Cow (Bovine) Monoclonal SELP Primary Antibody for FACS - ABIN181983
Massaguer, Engel, Tovar, March, Rigol, Solanes, Bosch, Pizcueta: Characterization of platelet and soluble-porcine P-selectin (CD62P). in Veterinary immunology and immunopathology 2003
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Mouse (Murine) Monoclonal SELP Primary Antibody for Func, FACS - ABIN335650
Matsumoto, Shigeta, Miyasaka, Hirata: CD43 plays both antiadhesive and proadhesive roles in neutrophil rolling in a context-dependent manner. in Journal of immunology (Baltimore, Md. : 1950) 2008
The study establishes that thrombotic-inflammatory pathways enhancing P-selectin exposure unrelated to treatment might be activated in patients, while the event rate remained lowered, and hence, treatment strategies should be inclusive to control these factors.
This study could not support the potential benefit of the high-dose vitamin D on plasma level of P-selectin and hs-CRP (show CRP Antibodies) in patients with VTE.
The level of d-dimer, P-selectin, and platelet count might be good candidate predictive markers for PVT in patients with cirrhotic PHT after devascularization. The combined test of the 3 markers can increase the value of prediction.
preliminary result indicated the beneficial effect of serine on the expression of SelP (show SEPP1 Antibodies) and GPx (show GPX1 Antibodies), which suggested that it might be a candidate for combined selenium supplement.
deletion of P-sel disrupted megakaryocyte/neutrophil interactions in spleen, reduced TGF-beta (show TGFB1 Antibodies) content, and corrected the hematopoietic stem cells distribution that in Gata1 (show GATA1 Antibodies)(low) mice, as in primary myelofibrosis patients, is abnormally expanded in spleen.
Elevated plasma P-selectin autoantibodies may play a role in the pathogenesis of thrombocytopenia in pSS (show CDSN Antibodies) patients.
The addition of sialic acid enhances the affinity of CD15 (show FUT4 Antibodies) to P-selectin and augments the cell adhesion to blood vessel endothelial cells.
This study provides a better understanding of the biology of P-selectin and PSGL-1 (show SELPLG Antibodies) and their roles in dissemination and resensitization of Multiple myeloma treatment.
Data (including data from studies in transgenic mice) suggest that sequence variations limited to 1.4-kb proximal promoter region account for most differences in expression of murine Selp (show SEPP1 Antibodies) and human SELP (show SEPP1 Antibodies) genes.
P-selectin gene polymorphisms and haplotypes can contribute to proliferative diabetic retinopathy development.
Despite the decrease of CD62P expression, the observed increased surface expression of CD41/61 on platelets in horses with recurrent airway obstruction may contribute to the formation of platelet aggregates in their respiratory system.
The present study supported the notion that CD62P accumulation during platelet storage is involved in mediating transfusion-related acute lung injury.
Holothurian glycosaminoglycan has emerged as a novel anti-cancer agent via blocking P-selectin-mediated malignant events of tumor metastasis.
P-selectin has a role in endothelial progenitor cells' inhibition of platelet function
Both platelet and endothelial cell P-selectin contribute to host defense during Klebsiella pneumosepsis.
Platelet infiltration into solid tumors occurs through a P-selectin-dependent mechanism and promotes tumor growth.
P-selectin promotes neutrophil extracellular trap (NET) formation and is a potential target for NET-related diseases.
P-selectin is an important adhesion molecule (show NCAM1 Antibodies) vital for infiltration of regulatory T cells into mouse mammary tumors
Administering human recombinant PTX3 (show PITX3 Antibodies) to wild-type mice induced endothelial dysfunction and increased blood pressure, an effect absent in P-selectin-deficient mice.
This gene encodes a 140 kDa protein that is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. This protein redistributes to the plasma membrane during platelet activation and degranulation and mediates the interaction of activated endothelial cells or platelets with leukocytes. The membrane protein is a calcium-dependent receptor that binds to sialylated forms of Lewis blood group carbohydrate antigens on neutrophils and monocytes. Alternative splice variants may occur but are not well documented.
CD62 antigen-like family member P
, granule membrane protein 140
, leukocyte-endothelial cell adhesion molecule 3
, platelet activation dependent granule-external membrane protein
, selectin, platelet
, granulocyte membrane protein
, platelet alpha-granule membrane protein
, CD62P antigen
, cell adhesion molecule