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Sema4a Proteins

(Sema Domain, Immunoglobulin Domain (Ig), Transmembrane Domain (TM) and Short Cytoplasmic Domain, (Semaphorin) 4A (Sema4a))
This gene encodes a member of the semaphorin family of soluble and transmembrane proteins. Semaphorins are involved in numerous functions, including axon guidance, morphogenesis, carcinogenesis, and immunomodulation. The encoded protein is a single-pass type I membrane protein containing an immunoglobulin-like C2-type domain, a PSI domain and a sema domain. It inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons. It is an activator of T-cell-mediated immunity and suppresses vascular endothelial growth factor (VEGF)-mediated endothelial cell migration and proliferation in vitro and angiogenesis in vivo. Mutations in this gene are associated with retinal degenerative diseases including retinitis pigmentosa type 35 (RP35) and cone-rod dystrophy type 10 (CORD10). Multiple alternatively spliced transcript variants encoding different isoforms have been identified.[provided by RefSeq, Sep 2010].
Sema4a Protein (AA 1-761) (GST tag) Sema4a Protein (AA 1-761) (GST tag) Sema4a Protein (AA 1-761) (GST tag) (ABIN1319469)

Sema4a Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA

Sema4a Protein (AA 33-132) (GST tag) Sema4a Protein (AA 33-132) (GST tag) Sema4a Protein (AA 33-132) (GST tag) (ABIN1319471)

Sema4a Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA

Sema4a Protein (His tag) Sema4a Protein (His tag) Sema4a Protein (His tag) (ABIN7320641)

Sema4a Origin: Mouse Host: Human Cells Recombinant > 95 % as determined by SDS-PAGE

Sema4a Proteins by Origin

Find Sema4a Proteins for a variety of species such as anti-Human Sema4a, anti-Mouse Sema4a. The species listed below are among those available. Click on a link to go to the corresponding products.

Sema4a Proteins by Source

Here you will find Sema4a Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

Sema4a Proteins by Protein Type

Here you can find Sema4a Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

Sema4a Proteins by Application

Find Sema4a Proteins validated for a specific application such as WB, AP, AA, ELISA. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Sema4a Proteins by Biological Activity

Find Sema4a Proteins with a specific Biological Activity. The Biological Activity listed below are among those available. Click on a link to go to the corresponding products.

Popular Sema4a Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
Cat. No. ABIN1319469
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1319471
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Human Cells
Validations
  • (1)
Cat. No. ABIN7320641
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
  • (1)
Cat. No. ABIN2181737
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
Cat. No. ABIN7520489
Quantity 50 μg
Datasheet Datasheet
Reactivity Mouse
Source Human Cells
Validations
Cat. No. ABIN4371022
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7386176
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source CHO Cells
Validations
Cat. No. ABIN6253441
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
Cat. No. ABIN7317490
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
Cat. No. ABIN7317489
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2731626
Quantity 20 μg
Datasheet Datasheet

Latest Publications for our Sema4a Proteins

Chiou, Lucassen, Sather, Kallianpur, Connor: "Semaphorin4A and H-ferritin utilize Tim-1 on human oligodendrocytes: A novel neuro-immune axis." in: Glia, Vol. 66, Issue 7, pp. 1317-1330, (2018) (PubMed).

Peng, Gao, Chong, Liu, Zhang: "Semaphorin 4A enhances lung fibrosis through activation of Akt via PlexinD1 receptor." in: Journal of biosciences, Vol. 40, Issue 5, pp. 855-62, (2015) (PubMed).

Mogie, Shanks, Nkyimbeng-Takwi, Smith, Davila, Lipsky, DeTolla, Keegan, Chapoval: "Neuroimmune semaphorin 4A as a drug and drug target for asthma." in: International immunopharmacology, Vol. 17, Issue 3, pp. 568-75, (2013) (PubMed).

Aliases for Sema4a Proteins

semaphorin 4A (SEMA4A) Proteins
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A (sema4a) Proteins
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A (Sema4a) Proteins
semaphorin 4A (Sema4a) Proteins
AI132332 Proteins
CORD10 Proteins
RP35 Proteins
SEMA4A Proteins
SEMAB Proteins
Semab Proteins
SEMB Proteins
SemB Proteins
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