You are viewing an incomplete version of our website. Please click to reload the website as full version.

anti-Senataxin (SETX) Antibodies

SETX encodes a protein named for its homology to the Sen1p protein of fungi which has RNA helicase activity encoded by a domain at the C-terminal end of the protein. Additionally we are shipping Senataxin Kits (2) and Senataxin Proteins (2) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SETX 23064 Q7Z333
SETX 269254 A2AKX3
SETX 362096  
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top anti-Senataxin Antibodies at antibodies-online.com

Showing 10 out of 113 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IP, WB Western Blot and Immunoprecipitation: Senataxin Antibody [ABIN252880] - Detection of Human Senataxin by Western Blot and Immunoprecipitation. Samples: Whole cell lysate (15 and 50 mcg for WB, 1 mg for IP, 20% of IP loaded) from HeLa cells. Antibodies: Affinity purified rabbit anti-Senataxin antibody ABIN252880 used for WB at 0.1 mcg/ml (A) and 1 mcg/ml (B) and used for IP at 3 mcg/mg lysate. Senataxin was also immunoprecipitated by rabbit anti-Senataxin antibody ABIN252881, which recognizes a downstream epitope. Detection: Chemiluminescence with exposure times of 3 minutes (A) and 30 seconds (B). Immunoprecipitation: Senataxin Antibody [ABIN2528802] - Samples: Whole cell lysate (0.5 or 1.0 mg per IP reaction; 20% of IP loaded) from HeLa cells prepared using NETN lysis buffer. Antibodies: Affinity purified rabbit anti-Senataxin antibody used for IP at 6 ug per reaction. Senataxin was also immunoprecipitated by a previous lot of this antibody and rabbit anti-Senataxin antibody. For blotting immunoprecipitated Senataxin, the antibody was used at 1 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes. 100 μL Log in to see 5 to 7 Days
$486.94
Details
Human Rabbit Un-conjugated ChIP, IP, WB Western Blot and Immunoprecipitation: Senataxin Antibody [ABIN252881] - Detection of Human Senataxin by Western Blot and Immunoprecipitation. Samples: Whole cell lysate (15 and 50 mcg for WB, 1 mg for IP, 20% of IP loaded) from HeLa cells. Antibodies: Affinity purified rabbit anti-Senataxin antibody ABIN252881 used for WB at 0.4 mcg/ml (A) and 1 mcg/ml (B) and used for IP at 3 mcg/mg lysate. Senataxin was also immunoprecipitated by rabbit anti-Senataxin antibody ABIN252880, which recognizes an upstream epitope. Detection: Chemiluminescence with exposure times of 3 minutes (A) and 30 seconds (B). 100 μL Log in to see 5 to 7 Days
$486.94
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), IP, WB Immunohistochemistry-Paraffin: Senataxin Antibody [NBP1-94712] - IHC analysis of a formalin fixed paraffin embedded tissue section of human heart (verticle section) using 1:200 dilution of lot A2 of Senataxin antibody. The antibody generated a very strong staining in the cytoplasm and the nuclei of the muscle cells. No signal was found in the perimysium & endomycium (connective tissue) of the section. Immunohistochemistry-Paraffin: Senataxin Antibody [NBP1-94712] - IHC analysis of a formalin fixed paraffin embedded tissue section of human heart (transverse section) using 1:200 dilution of lot A2 of Senataxin antibody. The antibody generated a very strong staining in the cytoplasm and the nuclei of the muscle cells. No signal was found in the perimysium & endomycium area (connective tissue) of the section. 0.1 mL Log in to see 5 to 7 Days
$408.19
Details
Human Mouse Un-conjugated IF Immunofluorescence of monoclonal antibody to SETX on HeLa cell  (antibody concentration 10 µg/mL). 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Mouse Un-conjugated FACS, IHC, IHC (p) Immunohistochemistry-Paraffin: Senataxin Antibody (4G1) [NBP2-52726] - Senataxin antibody clone 4G1 was tested on human prostate tissue sections and generated strong cytoplasmic-nuclear staining in the secretary/basal epithelial cells as well as the dense connective tissue. Flow (Intracellular): Senataxin Antibody (4G1) [NBP2-52726] - An intracellular stain was performed on HepG2 cells with Senataxin Antibody (4G1) antibody NBP2-52726 (blue) and a matched isotype control NBP2-27231 (orange). Cells were fixed with 4% PFA and then permeablized with 0.1% saponin. Cells were incubated in an antibody dilution of 5 ug/mL for 30 minutes at room temperature, followed by mouse F(ab)2 IgG (H+L) APC-conjugated secondary antibody (F0101B, R&D Systems). 0.1 mg Log in to see 5 to 7 Days
$381.94
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded muscle of mouse embryo labeled with Anti-Senataxin/SETX Polyclonal Antibody, Unconjugated (ABIN1385872) at 1:200, followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$295.90
Details
Human Rabbit Un-conjugated IHC, IHC (p) Immunohistochemistry: Senataxin Antibody [NBP2-13300] - Staining of human skeletal muscle shows moderate cytoplasmic positivity in myocytes. 0.1 mL Log in to see 8 to 11 Days
$439.69
Details
Human Mouse Un-conjugated IF, ELISA, WB Immunofluorescence of monoclonal antibody to SETX on HeLa cell. [antibody concentration 10 ug/ml] SETX monoclonal antibody (M05), clone 2A9. Western Blot analysis of SETX expression in NIH/3T3. 100 μg Log in to see 9 Days
$430.00
Details
Human Rabbit HRP IHC (p), WB   100 μL Log in to see 14 to 21 Days
$405.90
Details
Human Rabbit Alexa Fluor 594 IF (p)   100 μL Log in to see 14 to 21 Days
$405.90
Details

SETX Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , , , ,
,
,
, , , , , , , , , , , , , , , , , , ,
Mouse (Murine) , ,
,
,
, , , , , , , , , , ,
Rat (Rattus) , ,
,
,
, , , , , , , , , , ,

Top referenced anti-Senataxin Antibodies

  1. Human Polyclonal SETX Primary Antibody for IP, WB - ABIN252880 : Richard, Feng, Manley: A SUMO-dependent interaction between Senataxin and the exosome, disrupted in the neurodegenerative disease AOA2, targets the exosome to sites of transcription-induced DNA damage. in Genes & development 2013 (PubMed)

  2. Human Polyclonal SETX Primary Antibody for ChIP, IP - ABIN252881 : Zhao, Gish, Braunschweig, Li, Ni, Schmitges, Zhong, Liu, Li, Moffat, Vedadi, Min, Pawson, Blencowe, Greenblatt: SMN and symmetric arginine dimethylation of RNA polymerase II C-terminal domain control termination. in Nature 2016 (PubMed)

More Antibodies against Senataxin Interaction Partners

Human Senataxin (SETX) interaction partners

  1. Novel compound heterozygous mutations of SETX in Chinese AOA2 pedigree were identified, which broaden the mutation spectrum of SETX.

  2. The role of senataxin in regulating gene expression on a genome-wide scale in Ataxia (show USP14 Antibodies) oculomotor apraxia 2 neurons is described.

  3. these data indicate a potentially causal link among inborn errors in SETX, susceptibility to infection and the development of neurologic disorders.

  4. AOA2 with myoclonus associated with mutations in SETX and AFG3L2 (show AFG3L2 Antibodies)

  5. BRCA1/SETX complexes support a DNA repair mechanism that addresses R-loop-based DNA damage at transcriptional pause sites.

  6. Results identify novel genes related to senataxin function in normal and disease states.

  7. genetic variations in the senataxin gene may contribute to Alzheimer's disease pathogenesis in the Taiwanese Han population.

  8. Protein interaction analysis of senataxin and the ALS4 L389S mutant yields insights into senataxin post-translational modification and uncovers mutant-specific binding with a brain cytoplasmic RNA-encoded peptide.

  9. Description of a new SETX gene mutation, which when combined with a recognized SETX mutation results in ataxia (show USP14 Antibodies) with oculomotor apraxia type 2.

  10. This study report a Japanese SCAR1/AOA2 family with a homozygous nonsense mutation (p.Q1441X) of SETX that was identified by exome sequencing

Mouse (Murine) Senataxin (SETX) interaction partners

  1. Results identify novel genes related to senataxin function in normal and disease states.

  2. These data support key roles for senataxin in coordinating meiotic crossing-over with transcription and in gene silencing to protect the integrity of the genome.

Senataxin (SETX) Antigen Profile

Protein Summary

This gene encodes a protein named for its homology to the Sen1p protein of fungi which has RNA helicase activity encoded by a domain at the C-terminal end of the protein. The protein encoded by this gene contains a DNA/RNA helicase domain at its C-terminal end which suggests that it may be involved in both DNA and RNA processing. Mutations in this gene have been associated with ataxia-ocular apraxia-2 (AOA2) and an autosomal dominant form of juvenile amyotrophic lateral sclerosis (ALS4).

Gene names and symbols associated with anti-Senataxin (SETX) Antibodies

  • senataxin (SETX) antibody
  • senataxin (setx) antibody
  • senataxin (Setx) antibody
  • A130090N03 antibody
  • A930037J23Rik antibody
  • Als4 antibody
  • AOA2 antibody
  • AW060766 antibody
  • bA479K20.2 antibody
  • mKIAA0625 antibody
  • RGD1565575 antibody
  • SCAR1 antibody
  • Sen1 antibody
  • SETX antibody
  • wu:fj92h09 antibody

Protein level used designations for anti-Senataxin (SETX) Antibodies

senataxin , amyotrophic lateral sclerosis 4 , probable helicase senataxin-like , SEN1 homolog , amyotrophic lateral sclerosis 4 protein , probable helicase senataxin , amyotrophic lateral sclerosis 4 homolog , amyotrophic lateral sclerosis 4 protein homolog , DEAxQ-box helicase , tRNA splicing endonuclease regulator 1

GENE ID SPECIES
100066679 Equus caballus
417170 Gallus gallus
464815 Pan troglodytes
562474 Danio rerio
100090737 Ornithorhynchus anatinus
100145435 Xenopus (Silurana) tropicalis
100405920 Callithrix jacchus
100445729 Pongo abelii
100468613 Ailuropoda melanoleuca
100542448 Meleagris gallopavo
23064 Homo sapiens
269254 Mus musculus
362096 Rattus norvegicus
480691 Canis lupus familiaris
534284 Bos taurus
Selected quality suppliers for anti-Senataxin (SETX) Antibodies
Did you look for something else?