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anti-Sirtuin 3 (SIRT3) Antibodies

SIRT3 encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Additionally we are shipping SIRT3 Proteins (15) and SIRT3 Kits (13) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SIRT3 23410 Q9NTG7
SIRT3 64384 Q8R104
SIRT3 293615  
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Top anti-SIRT3 Antibodies at antibodies-online.com

Showing 10 out of 185 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Dog Rabbit Un-conjugated IHC, WB WB Suggested Anti-SIRT3  Antibody Titration: 0.2-1 µg/mL ELISA Titer: ... 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$229.00
Details
Dog Rabbit Un-conjugated WB WB Suggested Anti-SIRT3 Antibody Titration: 2.5ug/mlELISA Titer: 1:312... 100 μL Log in to see 2 to 3 Days
$229.00
Details
Hamster Rabbit Un-conjugated IHC (p), WB Western blot analysis of Sirt3 Antibody (C-term) (ABIN652184) in mouse... Western blot analysis of Sirt3 Antibody (C-term) (ABIN652184) in CHO c... 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Goat Un-conjugated ELISA, WB ABIN185498 (0.2µg/ml) staining of Human Liver lysate (35µg protein in ... 100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Rabbit Un-conjugated IHC (p), WB Formalin-fixed and paraffin-embedded human cancer tissue reacted with ... Western blot analysis of SIRT3 antibody (ABIN390178) in Y79 cell line ... 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Chicken Un-conjugated EIA, WB Western blot analysis of SIRT3 in mouse heart tissue lysate with SIRT3... 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Human Goat Un-conjugated WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Cow Rabbit Un-conjugated WB   0.1 mg Log in to see 6 to 8 Days
$456.50
Details

SIRT3 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human , , , ,
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Mouse (Murine) , , , ,
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Rat (Rattus) , , , ,
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Top referenced anti-SIRT3 Antibodies

  1. Human Polyclonal SIRT3 Primary Antibody for IHC (p), WB - ABIN390178 : Pillai, Sundaresan, Kim, Gupta, Rajamohan, Pillai, Samant, Ravindra, Isbatan, Gupta: Exogenous NAD blocks cardiac hypertrophic response via activation of the SIRT3-LKB1-AMP-activated kinase pathway. in The Journal of biological chemistry 2010 (PubMed)
    Show all 11 references for ABIN390178

  2. Cow (Bovine) Polyclonal SIRT3 Primary Antibody for WB - ABIN493464 : Jing, Gesta, Kahn: SIRT2 regulates adipocyte differentiation through FoxO1 acetylation/deacetylation. in Cell metabolism 2007 (PubMed)
    Show all 4 references for ABIN493464

  3. Dog (Canine) Polyclonal SIRT3 Primary Antibody for IHC, WB - ABIN2779610 : Onyango, Celic, McCaffery, Boeke, Feinberg: SIRT3, a human SIR2 homologue, is an NAD-dependent deacetylase localized to mitochondria. in Proceedings of the National Academy of Sciences of the United States of America 2002 (PubMed)
    Show all 3 references for ABIN2779610

  4. Hamster Polyclonal SIRT3 Primary Antibody for IHC (p), WB - ABIN652184 : Kawamura, Uchijima, Horike, Tonami, Nishiyama, Amano, Asano, Kurihara, Kurihara: Sirt3 protects in vitro-fertilized mouse preimplantation embryos against oxidative stress-induced p53-mediated developmental arrest. in The Journal of clinical investigation 2010 (PubMed)
    Show all 2 references for ABIN652184

  5. Human Polyclonal SIRT3 Primary Antibody for WB - ABIN374622 : Shi, Wang, Stieren, Tong: SIRT3, a mitochondrial sirtuin deacetylase, regulates mitochondrial function and thermogenesis in brown adipocytes. in The Journal of biological chemistry 2005 (PubMed)

  6. Human Polyclonal SIRT3 Primary Antibody for EIA, IHC (p) - ABIN358732 : Sundaresan, Samant, Pillai, Rajamohan, Gupta: SIRT3 is a stress-responsive deacetylase in cardiomyocytes that protects cells from stress-mediated cell death by deacetylation of Ku70. in Molecular and cellular biology 2008 (PubMed)

  7. Human Polyclonal SIRT3 Primary Antibody for EIA, WB - ABIN783622 : Guarente: Sirtuins as potential targets for metabolic syndrome. in Nature 2006 (PubMed)

  8. Human Polyclonal SIRT3 Primary Antibody for WB - ABIN2779611 : Bellizzi, Rose, Cavalcante, Covello, Dato, De Rango, Greco, Maggiolini, Feraco, Mari, Franceschi, Passarino, De Benedictis: A novel VNTR enhancer within the SIRT3 gene, a human homologue of SIR2, is associated with survival at oldest ages. in Genomics 2005 (PubMed)

More Antibodies against SIRT3 Interaction Partners

Human Sirtuin 3 (SIRT3) interaction partners

  1. Studies indicate that Many of the metabolic disorders have been associated with a reduction of sirtuins SIRT1 (show SIRT1 Antibodies) and SIRT3 at critical developmental windows throughout development.

  2. SIRT3 has a pro-proliferative function in melanoma

  3. Up-regulation of SIRT3 in prostate cancer suppressed the phosphorylation of Akt (show AKT1 Antibodies), leading to the ubiquitination and degradation of oncoprotein c-MYC (show MYC Antibodies).

  4. Study reveals a role of SIRT3/GSK-3beta (show GSK3b Antibodies)/Bax (show BAX Antibodies) signaling pathway in the suppression of HCC (show FAM126A Antibodies) growth.

  5. physiological significance of SIRT3 on HBx-induced oxidative stress

  6. Data suggest SIRT3-mediated inhibition of cell proliferation in B-cell malignancies is dependent on down-regulation of IDH2 (show IDH2 Antibodies) and SOD2 (show SOD2 Antibodies) activities via deacetylation; loss of SIRT3 stimulates cell proliferation via generation of reactive oxygen species.

  7. CDK1 (show CDK1 Antibodies)-mediated SIRT3 phosphorylation is a potential effective target to sensitize tumor cells to radiotherapy.

  8. further studies on SIRT3 will help uncover important new pathways driving the aging process--{REVIEW}

  9. Mitochondrial sirt3 participates in the development of Alzheimer's disease, in a transgenic mouse model, via mitochondrial dysfunction.

  10. Development of novel SIRT3 inhibitors, such as LC-0296, might enable the development of new targeted therapies to treat and improve the survival rate of patients with head and neck cancer.

Mouse (Murine) Sirtuin 3 (SIRT3) interaction partners

  1. CerS1 (show CERS1 Antibodies), -2, and -6 are hyperacetylated in the mitochondria of SIRT3-null mice.

  2. as compared to Sirt3 overexpressed and normal groups, the acetylation of IDH2 (show IDH2 Antibodies) and accumulation of ox-LDL were significantly higher in the Sirt3 inhibited group

  3. Sirt3-dependent deacetylation of SOD2 (show SOD2 Antibodies) plays a protective role against oxidative stress and meiotic defects in oocytes under maternal obese conditions.

  4. A mouse model of developmentally primed nonalcoholic steatohepatitis is c characterized by an altered cellular redox status, sirtuin (show SIRT1 Antibodies) abundance and clock gene expression.

  5. SIRT3 deacetylated and activated GSK-3beta (show GSK3b Antibodies) and thereby blocked TGF-beta1 (show TGFB1 Antibodies) signaling and tissue fibrosis.

  6. Sir3 dysfunction in Cmah-null mice altered various signaling pathways, which are responsible for age-related hearing loss.

  7. Ischemic postconditioning might prevent lethal reperfusion injury through an increased SIRT3 activity and subsequent attenuation of CyPD (show CYPD Antibodies) acetylation at reperfusion.

  8. Data showed the expression levels of SIRT1 (show SIRT1 Antibodies), SIRT3, and SIRT6 (show SIRT6 Antibodies) were decreased in the ovaries of aged mice and mice treated with chemotherapy, but increased in mice treated to caloric restriction suggesting these genes are closely related to ovarian reserve.

  9. SIRT3 and SIRT5 (show SIRT5 Antibodies) regulate the enzyme activity and cardiolipin binding of very long-chain acyl-CoA dehydrogenase (show ACADVL Antibodies)

  10. This study demonstrates the importance of SIRT3 in preserving heart function and capillary density in the setting of obesity.

Cow (Bovine) Sirtuin 3 (SIRT3) interaction partners

  1. The results indicate that the variations in the class I sirtuin (show SIRT1 Antibodies) genes and their corresponding genotypes may be considered as molecular markers for economic traits in cattle breeding.

  2. The expression profile of sirtuin 1 (show SIRT1 Antibodies) and sirtuin 3 in the liver, muscle, and adipose tissue of calves and bulls is reported.

SIRT3 Antigen Profile

Protein Summary

This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined\; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Two alternatively spliced transcript variants that encode different proteins have been described for this gene.

Gene names and symbols associated with anti-Sirtuin 3 (SIRT3) Antibodies

  • sirtuin (silent mating type information regulation 2 homolog) 3 (S. cerevisiae) (sirt3) antibody
  • sirtuin 3 (SIRT3) antibody
  • sirtuin (silent mating type information regulation 2 homolog) 3 (S. cerevisiae) (SIRT3) antibody
  • sirtuin 3 (Sirt3) antibody
  • 2310003L23Rik antibody
  • AI848213 antibody
  • Sir2l3 antibody
  • sirtuin antibody
  • zgc:158774 antibody

Protein level used designations for anti-Sirtuin 3 (SIRT3) Antibodies

sirtuin 3 , sirtuin , NAD-dependent deacetylase sirtuin-3, mitochondrial , NAD-dependent protein deacetylase sirtuin-3, mitochondrial , SIR2-like protein 3 , mitochondrial nicotinamide adenine dinucleotide-dependent deacetylase , regulatory protein SIR2 homolog 3 , silent mating type information regulation 2, S.cerevisiae, homolog 3 , sir2-like 3 , sirtuin type 3 , SIRT3 mitochondrial , NAD-dependent deacetylase sirtuin-3 , NAD-dependent protein deacetylase sirtuin-3 , SIRT3L mitochondrial , mSIR2L3 , mitochondrial protein lysine deacetylase , silent mating type information regulation 2, (S.cerevisiae, homolog)-like 3

GENE ID SPECIES
558775 Danio rerio
100604320 Nomascus leucogenys
422988 Gallus gallus
23410 Homo sapiens
475933 Canis lupus familiaris
100354500 Oryctolagus cuniculus
64384 Mus musculus
293615 Rattus norvegicus
101087609 Felis catus
614027 Bos taurus
100125971 Sus scrofa
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