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Sorbitol Dehydrogenase Proteins (SORD)

Sorbitol dehydrogenase (SORD\; EC 1.1.1.14) catalyzes the interconversion of polyols and their corresponding ketoses, and together with aldose reductase (ALDR1\; MIM 103880), makes up the sorbitol pathway that is believed to play an important role in the development of diabetic complications (summarized by Carr and Markham, 1995 [PubMed 8535074]). Additionally we are shipping Sorbitol Dehydrogenase Antibodies (129) and Sorbitol Dehydrogenase Kits (22) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SORD 20322 Q64442
SORD 6652 Q00796
SORD 24788 P27867
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Top Sorbitol Dehydrogenase Proteins at antibodies-online.com

Showing 10 out of 24 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 2 to 3 Days
$357.00
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 7 to 8 Days
$286.00
Details
HOST_Escherichia coli (E. coli) Human His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$739.20
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Human Human His tag   500 μg Log in to see 5 Days
$1,732.50
Details
Yeast Wild boar His tag   1 mg Log in to see 56 to 66 Days
$2,163.33
Details
Yeast Sheep His tag   1 mg Log in to see 56 to 66 Days
$2,964.50
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,968.17
Details

SORD Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , , ,
, ,
Rat (Rattus)

Top referenced Sorbitol Dehydrogenase Proteins

  1. Human SORD Protein expressed in Escherichia coli (E. coli) - ABIN667008 : Baker, Reeves, Hetherington, Aitken: Analysis of proteomic changes associated with sperm capacitation through the combined use of IPG-strip pre-fractionation followed by RP chromatography LC-MS/MS analysis. in Proteomics 2010 (PubMed)
    Show all 2 references for ABIN667008

More Proteins for Sorbitol Dehydrogenase (SORD) Interaction Partners

Mouse (Murine) Sorbitol Dehydrogenase (SORD) interaction partners

  1. Knockout mice had the highest sorbitol content among various genetic types including mice wwith human aldose reductase (show AKR1B1 Proteins).

  2. The zinc-finger protein ZAC1 (show PLAGL1 Proteins) is up-regulated under hypertonic stress and negatively regulates expression of sorbitol dehydrogenase, allowing for accumulation of sorbitol as a compatible organic osmolyte.

Human Sorbitol Dehydrogenase (SORD) interaction partners

  1. One of the most striking changes involved sorbitol dehydrogenase, a key enzyme in the polyol pathway. Validation studies revealed dramatically increased sorbitol dehydrogenase concentrations and activity in adenomas and cancer cell lines, along with important changes in the expression of other enzymes in the same (AKR1B1 (show AKR1B1 Proteins)) and related (KHK (show KHK Proteins)) pathways.

  2. The SDH level was significantly decreased in patients with proliferative compared with non-proliferative retinopathy in both insulin (show INS Proteins) and oral diabetic groups.

  3. Thus, our findings suggest that the -888G > C polymorphism in the SORD gene is not involved in the pathogenesis of diabtic retinopathy in type 2 diabetes.

  4. The expression of SORD is regulated by androgens in human prostate. In prostate cancer, increased immunostaining was associated with high Gleason patterns and high serum PSA (show PLAG1 Proteins) concentrations.

  5. crystals of sorbitol dehydrogenase belong to the monoclinic C2 space group, with unit-cell parameters a = 145.9, b = 52.3, c = 169.0 A, beta = 101.8 degrees

  6. Sorbitol dehydrogenase (SDH), a member of the medium-chain dehydrogenase/reductase protein family and the second enzyme of the polyol pathway of glucose metabolism, converts sorbitol to fructose strictly using NAD(+) as coenzyme.

  7. Results compare the catalytic mechanism of liver sorbitol dehydrogenase with wild-type and Glu154-->Cys (show DNAJC5 Proteins) forms of yeast xylitol dehydrogenase.

  8. The zinc-finger protein ZAC1 (show PLAGL1 Proteins) is up-regulated under hypertonic stress and negatively regulates expression of sorbitol dehydrogenase, allowing for accumulation of sorbitol as a compatible organic osmolyte.

Sorbitol Dehydrogenase (SORD) Protein Profile

Protein Summary

Sorbitol dehydrogenase (SORD\; EC 1.1.1.14) catalyzes the interconversion of polyols and their corresponding ketoses, and together with aldose reductase (ALDR1\; MIM 103880), makes up the sorbitol pathway that is believed to play an important role in the development of diabetic complications (summarized by Carr and Markham, 1995

Gene names and symbols associated with Sorbitol Dehydrogenase Proteins (SORD)

  • sorbitol dehydrogenase (sord)
  • sorbitol dehydrogenase (Sdh)
  • sorbitol dehydrogenase (LOC733025)
  • sorbitol dehydrogenase (polS)
  • sorbitol dehydrogenase (sdh)
  • sorbitol dehydrogenase (smoS)
  • sorbitol dehydrogenase (Rsph17029_1731)
  • Sorbitol dehydrogenase (Srd)
  • sorbitol dehydrogenase (RSKD131_1411)
  • sorbitol dehydrogenase (Sord)
  • sorbitol dehydrogenase (SORD)
  • BmSDH protein
  • MGC83437 protein
  • PSPTO0363 protein
  • SDH protein
  • Sdh-1 protein
  • Sdh1 protein
  • SODH-1 protein
  • sord protein
  • SORD1 protein

Protein level used designations for Sorbitol Dehydrogenase Proteins (SORD)

sorbitol dehydrogenase , L-iditol 2-dehydrogenase , mammalian sorbitol dehydrogenase homolog , sorbitol dehydrogenase 1

GENE ID SPECIES
446317 Xenopus laevis
496715 Xenopus (Silurana) tropicalis
692742 Bombyx mori
733025 Bombyx mori
1181972 Pseudomonas syringae pv. tomato str. DC3000
1220989 Ralstonia solanacearum GMI1000
3690081 Burkholderia pseudomallei 1710b
3719926 Rhodobacter sphaeroides 2.4.1
4897512 Rhodobacter sphaeroides ATCC 17029
5656982 Drosophila melanogaster
7358398 Rhodobacter sphaeroides KD131
9746093 Halomonas elongata DSM 2581
20322 Mus musculus
6652 Homo sapiens
415332 Gallus gallus
487535 Canis lupus familiaris
24788 Rattus norvegicus
101115280 Ovis aries
508954 Bos taurus
100158181 Sus scrofa
100173784 Pongo abelii
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