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SORD Protein (His tag)

SORD Origin: Human Host: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7319049
  • Target See all SORD Proteins
    SORD (Sorbitol Dehydrogenase (SORD))
    Protein Type
    Recombinant
    Origin
    • 8
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 7
    • 5
    • 2
    • 2
    • 1
    • 1
    Human Cells
    Purification tag / Conjugate
    This SORD protein is labelled with His tag.
    Purpose
    Recombinant Human SORD Protein (His Tag)
    Sequence
    Ala2-Pro357
    Characteristics
    Recombinant Human Sorbitol Dehydrogenase is produced by our Mammalian expression system and the target gene encoding Ala2-Pro357 is expressed with a 6His tag at the C-terminus.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product SORD Protein
  • Restrictions
    For Research Use only
  • Format
    Frozen, Liquid
    Buffer
    Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl,0.2M NaCl,5 mM DTT,20 % glycerol, pH 8.0.
    Storage
    -20 °C
    Storage Comment
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • Target
    SORD (Sorbitol Dehydrogenase (SORD))
    Alternative Name
    SORD (SORD Products)
    Synonyms
    SORD1 Protein, Sdh-1 Protein, Sdh1 Protein, Sodh-1 Protein, SDH Protein, sord Protein, MGC83437 Protein, BmSDH Protein, PSPTO0363 Protein, SODH-1 Protein, RATSDHE1 Protein, SDH2 Protein, Sdh Protein, Sdhe1 Protein, TDH Protein, 4733401P19Rik Protein, AI836084 Protein, CGI-97 Protein, SDS Protein, zgc:63674 Protein, sorbitol dehydrogenase Protein, sorbitol dehydrogenase L homeolog Protein, Sorbitol dehydrogenase Protein, serine dehydratase Protein, SBDS ribosome maturation factor Protein, SORD Protein, Sord Protein, sord.L Protein, sord Protein, Sdh Protein, LOC733025 Protein, polS Protein, RS_RS10765 Protein, sdh Protein, smoS Protein, Rsph17029_1731 Protein, Srd Protein, RSKD131_1411 Protein, SDS Protein, Sds Protein, Sbds Protein
    Background

    Background: Sorbitol dehydrogenase, also known as L-iditol 2-dehydrogenase and SORD, is a member of the zinc-containing alcohol dehydrogenase family. SORD exsits in a homotetramer and binds one zinc ion per subunit. SORD is expressed in kidney and epithelial cells of both benign and malignant prostate tissue. SORD can converts sorbitol to fructose and catalyzes the interconversion of polyols and their corresponding ketoses, and together with aldose reductase to make up the sorbitol pathway. SORD is up-regulated by androgens and down-regulated by castration. SORD may play a role in the sperm motility by providing an energetic source for sperm.

    Synonym: Sorbitol Dehydrogenase, L-Iditol 2-Dehydrogenase, SORD

    Molecular Weight
    39.3 kDa
    UniProt
    Q00796
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