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SP7 encodes a member of the Sp subfamily of Sp/XKLF transcription factors. Additionally we are shipping SP7 Antibodies (35) and SP7 Proteins (4) and many more products for this protein.
Showing 9 out of 12 products:
FGF and Wnt (show WNT2 ELISA Kits)/beta-Catenin (show CTNNB1 ELISA Kits) pathways act in part by directing transcription of osx to promote osteoblast differentiation at sites of bone formation.
Data show the endogenous sp7 gene expression in the otic placode and vesicle, and in forming skeletal structures in Tg(sp7:EGFP)b1212 line.
The expression of specific targets Smad1 (show GARS ELISA Kits) and Osterix was significantly increased in the presence of Pi and restored by coincubation with Mg(2 (show MUC7 ELISA Kits)+). As miR (show MLXIP ELISA Kits)-30b, miR (show MLXIP ELISA Kits)-133a, and miR (show MLXIP ELISA Kits)-143 are negatively regulated by Pi and restored by Mg(2 (show MUC7 ELISA Kits)+) with a congruent modulation of their known targets Runx2 (show RUNX2 ELISA Kits), Smad1 (show GARS ELISA Kits), and Osterix, our results provide a potential mechanistic explanation of the observed upregulation of these master switches of o
Preameloblast-Derived Factors Mediate Osteoblast Differentiation of Human Bone Marrow Mesenchymal Stem Cells by Runx2 (show RUNX2 ELISA Kits)-Osterix-BSP (show KLK6 ELISA Kits) Signaling.
Osx (show MID1 ELISA Kits) might function as a potential regulator for the proliferation and odontoblastic differentiation of hDPCs.
Data suggest that beta-catenin (beta-cat) signaling upregulates the expression of osterix (OSX) in pre-osteoblastic and bone marrow stromal cells.
The 2 genes RUNX1 (show RUNX1 ELISA Kits) and SP7 resulted differently expressed in cells cultured on metallic supports if compared with the expression recorded for OIC
c-Src (show SRC ELISA Kits) signaling modulates osteoblast differentiation at least in part through phosphorylation of Osterix.
Pin1 (show PIN1 ELISA Kits) regulates the osteogenic activity of Osterix.
Runx2 (show RUNX2 ELISA Kits)-Sp7 molecular complex functionally cooperate for maximal induction of cell-phenotype-restricted genes
Osterix is a novel target of protein kinase A, and protein kinase A modulates osteoblast differentiation partially through the regulation of Osterix.
results provide a molecular description of a mechanism for Osx (show MID1 ELISA Kits) and Runx2 (show RUNX2 ELISA Kits) transcriptional cooperation that is subject to further regulation by MAPK (show MAPK1 ELISA Kits)-activating signals during osteogenesis.
results suggest that expression of Sp7 during the early stage of Satb2 (show SATB2 ELISA Kits)-induced osteogenic differentiation of BMSCs is regulated by miR (show MLXIP ELISA Kits)-27a.
Fibrillin-2 (show FBN2 ELISA Kits) and periostin (show POSTN ELISA Kits) are target genes in Osterix-mediated osteoblast differentiation.
osterix is a downstream target of IGF1R (show IGF1R ELISA Kits) in chondrocytes.
cells expressing osterix are mesenchymal progenitors contributing to all relevant cell types during morphogenesis.
Results propose that Utx (show KDM6A ELISA Kits) plays important roles in osteoblast differentiation by controlling the expressions of Runx2 (show RUNX2 ELISA Kits) and Osterix.
Decreased expression of Osterix, as well as impaired TGFbeta and BMP2 signaling, contribute to the observed osteopenic bone phenotype of TIEG1 KO mice.
Intermittent stretching promotes osteogenic differentiation of bone marrow derived mesenchymal stem cells; the p38MAPK (show MAPK14 ELISA Kits)-osterix pathway has an important role in the control of osteogenesis related gene expression.
CHIP targets Osx for ubiquitination and degradation in osteoblasts after chronic exposure to TNF-alpha (show TNF ELISA Kits).
conclude that OSX, one of the key downstream molecules of NFIC (show NFIC ELISA Kits), plays a critical role in root, but not crown, formation
This gene encodes a member of the Sp subfamily of Sp/XKLF transcription factors. Sp family proteins are sequence-specific DNA-binding proteins characterized by an amino-terminal trans-activation domain and three carboxy-terminal zinc finger motifs. This protein is a bone specific transcription factor and is required for osteoblast differentiation and bone formation.
transcription factor Sp7
, transcription factor osterix
, Sp7 transcription factor
, transcription factor Sp7-like
, zinc finger protein osterix
, trans-acting transcription factor 7