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anti-Synaptotagmin II (SYT2) Antibodies

Synaptotagmins, like SYT2, are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis (Hilbush and Morgan, 1994. Additionally we are shipping Synaptotagmin II Proteins (7) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SYT2 127833 Q8N9I0
SYT2 20980 P46097
SYT2 24805 P29101
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Top anti-Synaptotagmin II Antibodies at

Showing 10 out of 76 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Rat Mouse Un-conjugated IP, WB 0.1 mg Log in to see 6 to 8 Days
Human Rabbit Un-conjugated WB WB Suggested Anti-SYT2 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Hela cell lysate WB Suggested Anti-SYT2  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500  Positive Control: Hela cell lysate 100 μL Log in to see 2 to 3 Days
Human Rabbit Un-conjugated IF 0.1 mL Log in to see 6 to 8 Days
Human Rabbit Un-conjugated WB SYT2 Antibody (Center) (ABIN657693) western blot analysis in NCI-H292 cell line lysates (35 µg/lane). This demonstrates the SYT2 antibody detected the SYT2 protein (arrow). 400 μL Log in to see 10 to 11 Days
Cow Goat Un-conjugated EIA, WB AP23235PU-N Synaptotagmin-2 antibody staining of Mouse Lung lysate at 0.1 µg/ml (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Log in to see 6 to 8 Days
Mouse Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
Human Rabbit Un-conjugated IF 100 μL Log in to see 14 Days
Human Goat Un-conjugated ELISA, WB 100 μg Log in to see 8 to 10 Days
Human Mouse Un-conjugated WB SYT2 monoclonal antibody (M01), clone 1G10 Western Blot analysis of SYT2 expression in HepG2. Detection limit for recombinant GST tagged SYT2 is approximately 0.1 ng/mL as a capture antibody. 0.1 mg Log in to see 8 to 11 Days
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days

SYT2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Synaptotagmin II Antibodies

  1. Rat (Rattus) Monoclonal SYT2 Primary Antibody for IP, WB - ABIN1449191 : Heald, Nogales: Microtubule dynamics. in Journal of cell science 2002 (PubMed)
    Show all 5 references for ABIN1449191

  2. Human Polyclonal SYT2 Primary Antibody for IF - ABIN401604 : Cnops, Hu, Burnat, Arckens: Influence of binocular competition on the expression profiles of CRMP2, CRMP4, Dyn I, and Syt I in developing cat visual cortex. in Cerebral cortex (New York, N.Y. : 1991) 2008 (PubMed)
    Show all 3 references for ABIN401604

More Antibodies against Synaptotagmin II Interaction Partners

Zebrafish Synaptotagmin II (SYT2) interaction partners

  1. knockdown of synaptotagmin 2 (syt2) reduces synchronous release, whereas knockdown of synaptotagmin 7 (syt7 (show SYT7 Antibodies)) reduces the asynchronous component of release.

Human Synaptotagmin II (SYT2) interaction partners

  1. SYT2 mutations cause a novel complex presynaptic congenital myasthenic syndrome characterized by motor neuropathy causing lower limb wasting and foot deformities, reflex potentiation following exercise and a prolonged period of posttetanic potentiation

  2. Synaptotagmin 2 mutations cause an autosomal-dominant form of lambert-eaton myasthenic syndrome and nonprogressive motor neuropathy.

  3. Human SytII is not an effective receptor for Botulinum neurotoxin D-C.

  4. synaptotagmin-II is not a high affinity receptor for BoNT/B (show BoNT/B Antibodies) and G due to a phenylalanine to leucine mutation in its luminal domain present only in humans and chimpanzees

  5. role for synaptotagmin II as calcium-sensor during phagocytosis and secretion in neutrophils

  6. both synaptotagmins I and II can interact with the syntaxin/synaptosomal-associated protein of 25 kDa (SNAP-25 (show SNAP25 Antibodies)) dimer

  7. WNK1 (show WNK1 Antibodies) selectively binds to and phosphorylates synaptotagmin 2 (Syt2) within its calcium binding C2 domains. Endogenous WNK1 (show WNK1 Antibodies) and Syt2 coimmunoprecipitate and colocalize on a subset of secretory granules in INS-1 (show FOXM1 Antibodies) cells.

  8. A recombinant fragment from the luminal domain of the human receptor protein syt (show SS18 Antibodies) II can bind specifically to botulinum neurotoxin B and its Hc domain.

  9. Mutation of overexpressed Syt2 transgene leaves intrinsic calcium sensitivity of vesicles intact while it destabilizes the readily releasable pool of vesicles and loosens the tight coupling between calcium influx and release.

Mouse (Murine) Synaptotagmin II (SYT2) interaction partners

  1. The 2.3-A structure of a ternary complex of botulinum neurotoxin type B (show BoNT/B Antibodies) bound to both its protein receptor synaptotagmin II and its ganglioside receptor GD1a, is reported.

  2. Synaptotagmins 1 and 2 as mediators of rapid exocytosis at nerve terminals: the dyad hypothesis

  3. Syt2 make it an excellent marker for analyzing the development and plasticity of perisomatic inhibitory innervations onto both excitatory and inhibitory neurons in the visual cortex.

  4. Syt2 increases the dynamic range of synapses by driving release with a high Ca(2 (show CA2 Antibodies))+ cooperativity, as well as by suppressing a remaining, near-linear Ca(2 (show CA2 Antibodies))+ sensor.

  5. Transient expression of Syt2 is no longer detected in cochlear inner hair cells (IHCs) after the onset of hearing, indicating that the most common calcium-sensors in central nervous system synapses are not involved in mature IHC ribbon synapse.

  6. SYT2 was a negative regulator of chemotaxis

  7. The readily releasable pool was rescued by Syt2 overexpression. The kinetics of fusion was slightly slower than in cells expressing Syt1. Syt2 has a lower Ca2+ affinity for phospholipid binding than Syt1 because of a difference in the C2A domain.

  8. Data suggest that synaptotagmins 1 and 2 perform equivalent functions in the Ca2 (show CA2 Antibodies)+ triggering of action potential-induced neurotransmitter release and in the restriction of spontaneous release.

  9. Synaptotagmin-2 is an essential synaptotagmin isoform that functions in concert with other synaptotagmins in the calcium-ion triggering of neurotransmitter release.

  10. The cell-, temporal-, and species-specific expression of synaptotagmin isoforms suggests that each may have distinct functions in neurotransmitter release

Synaptotagmin II (SYT2) Antigen Profile

Protein Summary

Synaptotagmins, like SYT2, are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis (Hilbush and Morgan, 1994

Gene names and symbols associated with anti-Synaptotagmin II (SYT2) Antibodies

  • synaptotagmin-2-like (LOC100146749) antibody
  • synaptotagmin IIa (syt2a) antibody
  • synaptotagmin II (syt2) antibody
  • synaptotagmin II (SYT2) antibody
  • synaptotagmin II (Syt2) antibody
  • synaptotagmin-like 2 (SYTL2) antibody
  • mKIAA4194 antibody
  • R74640 antibody
  • RATSYNII antibody
  • si:ch211-236j4.1 antibody
  • SYNII antibody
  • SytII antibody

Protein level used designations for anti-Synaptotagmin II (SYT2) Antibodies

synaptotagmin II , synaptotagmin 2 , synaptotagmin-2 , sytII

100146749 Equus caballus
567877 Danio rerio
100158469 Xenopus (Silurana) tropicalis
100511582 Sus scrofa
100594116 Nomascus leucogenys
127833 Homo sapiens
20980 Mus musculus
24805 Rattus norvegicus
100300626 Bos taurus
396327 Gallus gallus
485154 Canis lupus familiaris
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